
Muscle fibres are composed of proteins, with myosin being the most abundant protein, constituting approximately 54% of the total protein of the fibrils. Actin and tropomyosin are also present, with actin making up the thin filaments of the I bands. Skeletal muscle fibres are classified into two types: type 1 and type 2, with type 2 further divided into subtypes 2A and 2B. Type 1 and 2A fibres can use oxygen to generate energy for movement, while type 2B fibres rely on anaerobic glycolysis and have a white appearance due to a lower number of mitochondria. Smooth muscle fibres are found in internal organs and eyes, controlling functions such as digestion and pupil size, while cardiac muscle fibres are only found in the heart and have their own rhythm, contracting in a coordinated manner to enable the heart to beat.
| Characteristics | Values |
|---|---|
| Types | Slow oxidative (SO), fast oxidative (FO), fast glycolytic (FG), type 1, type 2A, type 2B |
| Composition | Myosin, actin, and tropomyosin |
| Appearance | Striated (skeletal and cardiac), non-striated (smooth) |
| Shape | Oblong (smooth), long and cylindrical (skeletal) |
| Length | Up to 30 cm (skeletal) |
| Diameter | Up to 100 μm (skeletal), 1.2 μm (myofibrils) |
| Location | Skeletal (limbs), cardiac (heart), smooth (internal organs and eyes) |
| Contraction | Controlled by nervous system (skeletal), through depolarization and pacemaker cells (cardiac), involuntary (smooth) |
| Blood supply | Richly supplied by blood vessels (skeletal), primary artery (skeletal) |
| Connective tissue | Epimysium, perimysium, endomysium (skeletal) |
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What You'll Learn

Skeletal muscle fibres
The basic functional units of the muscle fibre are called sarcomeres, which are necessary for muscle contraction. Before a skeletal muscle fibre can contract, it must receive an impulse from a nerve cell. This nerve impulse causes a change in electric charge, known as depolarization, which leads to a complex chain reaction within the muscle fibre, resulting in muscle contraction. Skeletal muscles have an abundant supply of blood vessels and nerves, which provide the necessary energy and stimulation for contraction.
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Smooth muscle fibres
Smooth muscle plays a vital role in the body's ability to maintain basic functions. For example, smooth muscle in the stomach and intestines helps with digestion and nutrient collection, while smooth muscle in the urinary system helps the body get rid of toxins and maintain electrolyte balance. Smooth muscle in the airways is responsible for conditions such as asthma, where the airways narrow due to bronchoconstriction, leading to breathing difficulties. Smooth muscle is also found in the skin and allows hair to raise in response to cold temperatures or fear.
At a cellular level, smooth muscle consists of thick and thin filaments that are not arranged into sarcomeres, giving it a non-striated pattern. The filaments are made up of proteins, including actin, myosin, and tropomyosin, with actin and myosin being the main proteins involved in muscle contraction. Actin filaments attach to dense bodies spread throughout the cell, and these can be observed under an electron microscope. The calcium-containing sarcoplasmic reticulum also aids in sustaining contraction.
The smooth muscle cell is 3-10 µm thick and 20-200 µm long. The actin and myosin form continuous chains within the smooth muscle cell, which are anchored at the dense bodies. The intermediate and thin filaments formed by these chains can then stretch to dense bodies located on adjacent smooth muscle cells, forming a mesh-like network. This allows the smooth muscle cells to contract uniformly in a spiral corkscrew fashion.
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Cardiac muscle fibres
Muscle fibres are made of protein. There are three types of muscle tissue in the body, each with its own unique characteristics. One of these is cardiac muscle, also known as myocardium. Cardiac muscle is found in the heart and is responsible for its contraction. This muscle is involuntary, meaning that we have no control over it.
Cardiac muscle cells, or cardiomyocytes, are the contracting cells that allow the heart to pump blood. Each cardiomyocyte is connected to its neighbour by intercalated discs, forming long fibres. These discs enable the rapid transmission of electrical impulses, allowing the muscle to contract in a coordinated manner. The cardiomyocytes are surrounded by an extracellular matrix, which is composed of proteins such as collagen and elastin, as well as glycosaminoglycans.
The fundamental contractile units of cardiac muscle cells are sarcomeres, which are composed of thick and thin filaments of the proteins actin and myosin. These filaments slide past each other during contraction. The thick filaments are composed of myosin, while the thin filaments are made of actin. The interaction between these filaments forms the basis of the sliding filament theory, which explains muscle contraction.
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Muscle fibre composition
Muscle fibres are composed of proteins, with three proteins in particular being concerned with their make-up: myosin, actin, and tropomyosin. Myosin is the most abundant protein, constituting approximately 54% of the total protein of the fibrils, while actin makes up about 20-25% and tropomyosin only 11%. These proteins are organised into organelles called myofibrils, which run the length of the cell and contain sarcomeres connected in series.
Sarcomeres are the smallest functional unit of a skeletal muscle fibre and are a highly organised arrangement of contractile, regulatory, and structural proteins. They are about 2 to 3 μ in length and are constructed of filaments that lie parallel to the long axis of the fibre, overlapping each other. There are two kinds of these filaments, with one being about twice the diameter of the other, and they alternate along the length of the fibril, overlapping and interlocking with each other. The thick filaments are composed of myosin and are located in the "A" bands, while the thin filaments are composed of actin and are located in the "I" bands.
Skeletal muscle fibres are classified into two types: type 1 and type 2. Type 1 fibres utilise oxygen to generate energy for movement and have a higher density of energy-generating organelles called mitochondria, which makes them dark. Type 2 fibres are further classified into subtypes 2A and 2B. Type 2A fibres can also use oxygen to generate energy, but type 2B fibres do not; instead, they store energy that can be used for short bursts of movement. Type 2B fibres have even less mitochondria than type 2A fibres and appear white.
In addition to the above, there are three types of muscle fibres based on their oxidative and glycolytic capacities: slow oxidative (SO), fast oxidative (FO), and fast glycolytic (FG). Most skeletal muscles contain all three types, although in varying proportions. Muscle fibres can adapt to changing demands by changing size or fibre type composition, which serves as the basis for physical therapy interventions aimed at increasing a patient's force development or endurance.
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Muscle fibre function
Muscle fibres are single muscle cells that work together to generate movement in the body and internal organs. There are three types of muscle tissue: skeletal, smooth, and cardiac. Each of these muscle tissues has muscle fibres, and each muscle fibre contains smaller units made up of repeating thick and thin filaments. This gives the muscle tissue a striated, or striped, appearance.
Skeletal muscle fibres are attached to the skeleton by tendons and control the voluntary movements of the body, such as walking, bending over, and picking up objects. They also serve other purposes, including producing movement, sustaining body posture and position, maintaining body temperature, storing nutrients, and stabilizing joints. Skeletal muscle fibres can be further classified into two types: type 1 and type 2. Type 1 fibres utilize oxygen to generate energy for movement and have a higher density of mitochondria. Type 2 fibres can be further subdivided into type 2A and type 2B. Type 2A fibres can also use oxygen to generate energy, while type 2B fibres do not use oxygen and instead store energy for short bursts of movement.
Smooth muscle fibres are involuntary and are found in internal organs and eyes. They are responsible for functions such as moving food through the digestive tract and changing pupil size. Smooth muscle fibres have an oblong shape and are much shorter than skeletal muscle fibres. They do not have a striated appearance like skeletal and cardiac muscle fibres.
Cardiac muscle fibres are found in the heart and are also involuntary. They contract in a coordinated way to allow the heart to beat. Cardiac muscle fibres have their own rhythm, with special pacemaker cells generating impulses that cause the cardiac muscle to contract. These fibres are branched and interconnected.
The function of muscle fibres can be influenced by various factors, including genetics and training. The proportion of fast-twitch and slow-twitch fibres in an individual's muscles is determined by their genetics, with people excelling at sprint events tending to have a higher number of fast-twitch fibres, while those who perform well in endurance sports have a higher number of slow-twitch fibres. However, training can modify the characteristics of these fibres, improving their power or endurance capabilities.
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Frequently asked questions
Muscle fibres are made of proteins, including myosin, actin, and tropomyosin. Myosin is the most abundant protein, constituting approximately 54% of the total protein of the fibrils. Actin and myosin are the two most significant myofilaments that make up the contractile elements of the muscle fibre.
There are three types of muscle fibres: slow oxidative (SO), fast oxidative (FO), and fast glycolytic (FG). Most skeletal muscles contain all three types, but in varying proportions. Skeletal muscle fibres are further classified into two types: type 1 and type 2. Type 2 is further divided into subtypes 2A and 2B.
Muscle fibres work with muscles to cause movement in the body. Skeletal muscle fibres, in particular, are responsible for contraction, which allows for specific movements of bones.
Muscle fibres receive an impulse from a nerve cell before they can contract. This impulse causes a change in electric charge called depolarization, which leads to a complex chain reaction within the muscle fibres, resulting in contraction.











































