Dominic Stone
Keppra, or levetiracetam, is an anti-epileptic drug used to treat certain types of seizures. It is also used to help improve spasticity and spasms in people with multiple sclerosis. While it is a helpful medication, it can cause a range of side effects, from mild to severe, including allergic reactions, drowsiness, dizziness, and mood and behavioral changes. In rare cases, it has also been suspected to cause rhabdomyolysis, a condition involving the fusion and necrosis of skeletal muscle cells, leading to myalgia and weakness.
| Characteristics | Values |
|---|---|
| Muscle Spasms | Levetiracetam, the active ingredient in Keppra, is used to help improve spasticity and spasms in people with multiple sclerosis. |
| Mechanism of Action | Levetiracetam works by decreasing abnormal excitement in the brain, although its precise mechanism of action is unknown. |
| Dosage | Levetiracetam is to be taken orally, usually twice a day (except for the long-acting formulation, which is taken once daily), with or without food. |
| Side Effects | Common side effects include dizziness, drowsiness, tiredness, weakness, aggressiveness, irritability, loss of appetite, stuffy nose, and infection. Rare side effects include serious skin reactions (e.g., Stevens-Johnson syndrome), allergic reactions, blood disorders, and mood and behavior changes. |
| Precautions | Do not stop taking levetiracetam suddenly, as it may cause withdrawal symptoms such as changes in behavior or mood. Do not drive or operate machinery if you experience drowsiness or dizziness. |
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What You'll Learn
Levetiracetam can cause drowsiness, dizziness, and tiredness
Levetiracetam, also known by the brand name Keppra, is an anti-epileptic drug used to treat certain types of seizures. It is also used to help improve spasticity and spasms in people with multiple sclerosis. While Levetiracetam can be effective in managing these conditions, it is important to be aware of its potential side effects, which may vary between individuals.
One of the known side effects of Levetiracetam is that it can cause drowsiness and tiredness, leading to decreased alertness and impaired coordination. This side effect can impact daily activities such as driving or operating machinery, so it is crucial for patients taking Levetiracetam to refrain from such activities until they understand how the medication affects them. If side effects do not subside within one to two weeks, it is recommended to consult a doctor, who may adjust the dosage or explore alternative treatments.
Dizziness is another common side effect associated with Levetiracetam. This can be particularly concerning for individuals prone to falls or those engaged in activities that require balance and coordination. It is advisable to be cautious and avoid situations where dizziness could lead to accidents until the effects of the medication are fully understood.
In addition to drowsiness, dizziness, and tiredness, Levetiracetam may also cause mood and behavior changes, problems with coordination, and unusual tiredness or weakness. Some patients have reported experiencing aggression, agitation, anger, anxiety, mood swings, depression, and irritability. It is important to closely monitor any changes in mood or behavior and inform a healthcare provider if these symptoms occur.
While Levetiracetam can cause these side effects, it is important to note that not everyone will experience them. The occurrence and severity of side effects can vary between individuals. Additionally, as with any medication, it is crucial to consult a healthcare professional before starting or stopping Levetiracetam to ensure it is safe and appropriate for your specific circumstances.
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It can also lead to allergic reactions, including DRESS
Keppra (levetiracetam) is an anti-epileptic drug that can cause a range of side effects, from mild to severe. While it is not explicitly mentioned that Keppra causes muscle spasms, it is used to treat certain types of seizures and can help improve spasticity and spasms in people with multiple sclerosis.
Now, regarding allergic reactions, including DRESS (Drug Reaction with Eosinophilia and Systemic Symptoms), it is important to note that levetiracetam can indeed cause allergic reactions. DRESS is a type of allergic reaction that can affect multiple organs, including the liver, kidneys, and heart. This condition is also known as multiorgan hypersensitivity. If you experience any symptoms of a serious allergic reaction, such as a rash, painful red or purple skin, or other unusual symptoms, stop taking the medication and seek immediate medical assistance.
Additionally, levetiracetam can cause severe skin reactions, such as Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN), which can be life-threatening if not treated promptly. Other possible side effects of levetiracetam include mood and behavior changes, such as aggression, anxiety, irritability, and depression. It may also cause hallucinations or psychotic-like behaviors. In rare cases, it may induce suicidal thoughts or actions. Furthermore, levetiracetam can lead to decreased alertness or coordination, blood disorders, and changes in mood or behavior.
It is always important to consult a healthcare professional if you experience any unusual or concerning symptoms while taking Keppra or any other medication. They can provide personalized advice and guidance based on your specific situation.
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May cause changes in mood and behaviour
Keppra, also known as Levetiracetam, is a medication used to treat certain types of seizures. It is an anticonvulsant medication, which means it helps to reduce the frequency of seizures. While Keppra can be effective in treating seizures, it may also cause changes in mood and behaviour in some individuals.
Some people taking Keppra have reported experiencing mood-related side effects, such as anxiety, agitation, irritability, and depression. These mood changes can range from mild irritability to more severe symptoms such as aggression and suicidal thoughts. It is important for individuals taking Keppra to monitor their mood and be aware of any unusual thoughts or behaviours. If someone taking Keppra notices any concerning changes in their mood or behaviour, they should seek medical advice.
In addition to mood changes, Keppra has also been associated with behavioural problems. Some individuals may experience increased aggression, anxiety, nervousness, or hostility. These behavioural changes can be particularly challenging for caregivers and can impact the individual's ability to interact with others. It is important for caregivers and loved ones to be aware of these potential side effects and seek support if needed.
While the mood and behavioural changes associated with Keppra can be concerning, they are typically mild and may not be significantly different from the individual's baseline behaviour. Additionally, the benefits of Keppra in treating seizures may outweigh the adverse effects. Close clinical monitoring and dose adjustment can help manage these side effects effectively, ensuring the benefits of the medication outweigh any potential risks.
It is worth noting that not everyone will experience mood and behavioural changes while taking Keppra. However, it is important to be aware of these potential side effects and seek medical advice if any concerning symptoms arise. Individuals taking Keppra should also be cautious when consuming alcohol, as it may worsen certain side effects, such as drowsiness and dizziness.
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Can cause blood disorders
Keppra (levetiracetam) is an anticonvulsant medication used in the treatment of certain types of seizures. It is also available as an orally disintegrating tablet (ODT) and can be taken with or without food.
Levetiracetam may cause blood disorders, including:
- Low white blood cell levels (leukopenia)
- Low neutrophil levels (neutropenia)
- Low red blood cell levels (anaemia)
- High eosinophil levels (eosinophilia)
People taking levetiracetam may experience a reduction in the number of cells that fight infection in the body (white blood cells). If you experience fever, sore throat, fatigue, weakness, or generally feel unwell while taking levetiracetam, contact your doctor as soon as possible. Your doctor will perform regular blood tests to monitor the number of specific types of blood cells in your blood.
It is important to note that levetiracetam may also cause other side effects, including changes in mood and behaviour, problems with coordination, and unusual tiredness or weakness. Serious skin reactions, such as Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN), can also occur and may lead to death if not treated. If you develop a rash, stop taking levetiracetam and seek medical help immediately.
Additionally, levetiracetam may interact with other medications, such as alcohol, caffeine, nicotine, and street drugs. It is important to inform your doctor about all prescription, over-the-counter, herbal medications, and supplements you are taking to ensure safe use.
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Can cause serious skin reactions
Keppra (levetiracetam) is a prescription drug used to treat certain types of seizures. Like most drugs, it can cause a range of side effects, including serious skin reactions.
Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) are two types of severe skin reactions that can occur with this medication. These reactions can lead to painful red or purple skin that looks burned and peels off. If left untreated, these reactions can be life-threatening. Therefore, it is crucial to stop taking levetiracetam and seek immediate medical attention if you experience any symptoms of SJS or TEN.
Other signs and symptoms that may indicate a serious skin reaction include blistering, peeling, or loosening of the skin, chills, cough, diarrhoea, itching, joint or muscle pain, red irritated eyes, red skin lesions, sore throat, sores, ulcers, or white spots in the mouth or on the lips. Experiencing unusual tiredness or weakness while taking this medication should also prompt medical consultation.
It is important to note that you should not discontinue Keppra without first consulting your doctor. Suddenly stopping this medication can cause seizures to return or occur more frequently. Your doctor may advise gradually reducing the dosage before stopping completely. Additionally, ensure that any other treating physicians or dentists are aware of your Keppra usage, as it may impact the results of certain medical tests.
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Frequently asked questions
Keppra (levetiracetam) is a prescription drug used to treat certain types of seizures. It is also used to help improve spasticity and spasms in people with multiple sclerosis.
There is limited evidence that levetiracetam can cause rhabdomyolysis, a condition that involves the fusion and necrosis of skeletal muscle cells, resulting in myalgia and weakness. However, the incidence of this condition is generally low, and it has been challenging to determine whether Keppra or other medications caused it.
Common side effects of Keppra include dizziness, drowsiness, tiredness, weakness, aggressiveness, irritability, loss of appetite, stuffy nose, and infection. It can also cause changes in mood and behaviour, such as aggression, agitation, anger, anxiety, lack of interest, mood swings, depression, hostility, and irritability.
If you experience any side effects from taking Keppra, it is important to consult your doctor or healthcare provider. They may advise adjusting the dosage or switching to a different medication. Do not stop taking Keppra suddenly without consulting your doctor, as this may cause seizures to return or occur more frequently.
