
Muscle relaxers are medications that act on the central nervous system to reduce muscle tone and alleviate spasms. They can also relax blood vessels, decreasing vascular resistance and causing a drop in blood pressure. While muscle relaxers do not directly cause weight gain, their sedative effects can lead to reduced physical activity, which may result in weight gain. Additionally, muscle injuries themselves can limit mobility and physical activity, further contributing to potential weight gain. Certain muscle relaxants, such as cyclobenzaprine, have been associated with weight gain and other side effects like drowsiness, dizziness, and dry mouth. However, weight gain is not a common side effect of all muscle relaxers, and the impact on weight may vary depending on the specific medication and individual factors.
| Characteristics | Values |
|---|---|
| Do muscle relaxers cause weight gain? | Muscle relaxers do not directly cause weight gain, but the reduced mobility of the injury and the sedative effects of the medications can result in weight gain as a result of decreased activity. |
| Drugs causing weight gain | Cyclobenzaprine, methocarbamol, orphenadrine, Fexmid (cyclobenzaprine), Zanaflex (tizanidine) |
| Drugs not causing weight gain | Methocarbamol |
| Side effects | Dizziness, drowsiness, impaired thinking, decreased ability or interest in making good nutrition choices, constipation, dry mouth, itching, blurred vision, allergic reaction, serotonin syndrome, nausea, vomiting, stomach upset, convulsive seizures, redness, pain, tissue death, skin shedding |
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What You'll Learn

Muscle relaxers are not direct causes of weight gain
Muscle relaxers are commonly prescribed to treat back pain and other muscle injuries. When a muscle is injured, it undergoes twitching and spasms, causing further damage to the muscle. Muscle relaxers help by preventing these contractions and allowing the muscle to heal. By using these medications, individuals can continue to exercise injured muscles, maintain their fitness levels, and prevent weight gain caused by inactivity.
While muscle relaxers can be beneficial in managing acute musculoskeletal conditions, they may also have side effects. Common side effects include drowsiness, dizziness, and constipation. In older adults, muscle relaxers can cause cognitive impairment, leading to a decreased ability or interest in making nutritious food choices. As a result, they may experience significant weight gain if the medication is used for chronic pain management.
Additionally, long-term use or abuse of muscle relaxers can lead to more significant weight gain. As the sedative effects of the medication contribute to reduced physical activity over an extended period, individuals may experience weight gain as a secondary consequence. However, it is important to note that this weight gain is not a direct result of the muscle relaxers themselves but rather the decrease in overall physical activity.
Furthermore, muscle relaxers can have more severe side effects, especially in older adults. These adverse effects include dependency and overdose, underscoring the importance of following a healthcare provider's treatment regimen. By adhering to the recommended usage, individuals can benefit from faster healing times and lower the risk of side effects, including weight gain.
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Reduced physical activity may lead to weight gain
Muscle relaxants can cause drowsiness, dizziness, and blurred vision, which may reduce physical activity. While weight gain was not reported as a side effect of muscle relaxants in studies, some people taking the medication have reported weight gain since its approval. It is unclear whether this weight gain was caused by the medication or other factors.
Regular physical activity is essential for maintaining weight loss. While most weight loss occurs due to decreasing calorie intake, physical activity helps burn calories and prevent weight regain. Additionally, physical activity can improve energy and macronutrient balance regulation, reducing the risk of stress-induced weight gain.
Some studies have shown that exercise can lead to weight loss. For example, Donnelly et al. demonstrated clinically significant weight loss in a group of overweight or obese individuals with supervised exercise. Slentz et al. also found that exercise without a reduction in caloric intake resulted in body mass and fat mass loss.
However, it is challenging for some individuals to engage in regular exercise programs and make them a part of their lifestyle. This may be due to the physical limitations caused by muscle spasms, pain, or injury, which can be managed with muscle relaxants. Therefore, it is essential to consult a doctor or healthcare professional for advice and to discuss any concerns about weight gain or the impact of medications.
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Muscle relaxers can cause drowsiness and impaired thinking
Muscle relaxers are a class of drugs including carisoprodol, cyclobenzaprine, naproxen, and diazepam. They are central nervous system depressants and act on your body by slowing down brain activity and causing skeletal muscle relaxation. While muscle relaxers do not directly cause weight gain, they can lead to weight gain as a result of decreased physical activity.
Drowsiness is a common side effect of muscle relaxers, with about 1 in 10 people experiencing this symptom. It is caused by the sedative effects of the medication, which slow down the central nervous system. This can lead to a decrease in overall physical activity, which may contribute to weight gain over time.
Impaired thinking and cognitive impairment are also potential side effects of muscle relaxers. These medications can affect your ability to think clearly and make decisions, including those related to nutrition. This may lead to poor nutrition choices and, in some cases, significant weight gain, especially in older adults.
It is important to note that the side effects of muscle relaxers can vary from person to person and may depend on the specific medication and dosage. If you are experiencing drowsiness, impaired thinking, or other side effects while taking muscle relaxers, it is important to consult your doctor or healthcare provider. They can provide guidance on managing side effects and adjusting your treatment plan if necessary.
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Older adults are at risk of significant weight gain
Muscle relaxers are central nervous system depressants that slow down brain activity and cause skeletal muscle relaxation. While these medications can be useful in treating various ailments, including back and muscle injuries, they can also lead to weight gain, especially in older adults.
Older adults are at a higher risk of experiencing side effects from muscle relaxers due to age-related changes in their bodies. Specifically, the body's ability to process and clear medications declines with age, and older adults are more likely to have impaired liver or kidney function. This can enhance the sedating side effects of muscle relaxers, leading to sedation, confusion, urinary retention, or memory problems. Additionally, older adults typically take multiple medications and supplements, increasing the risk of drug interactions that intensify the side effects of muscle relaxers.
The use of muscle relaxers can lead to a decrease in overall physical activity, which is a significant contributor to weight gain. When muscles are injured, they twitch and spasm, causing pain and further injury. Muscle relaxers help by reducing these reactions and allowing the muscles to heal. However, this reduced activity can result in weight gain, especially if the medication is used for an extended period. Short-term use of muscle relaxers may cause slight weight gain of 2 to 3 lbs, while long-term use or abuse can lead to more significant weight gain.
Older adults are particularly susceptible to the impact of muscle relaxers on their physical activity levels. They may experience significant weight gain if the medication is used to manage a chronic pain condition. The decreased ability or interest in making nutritious food choices, coupled with reduced physical activity, can compound the risk of weight gain in this population.
It is important to note that muscle relaxers are generally not recommended for long-term use, as the risk of side effects, including weight gain, typically outweighs the potential benefits. If long-term treatment is necessary, it is essential to be aware of the risk of weight gain and the potential for addiction. Discussing these risks with a doctor and considering non-drug therapies, such as massage therapy or strength training, is advisable before prescribing muscle relaxers to older adults.
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Muscle relaxers are linked to constipation
Muscle relaxers are commonly used to treat back pain and other muscle injuries. They are particularly useful in managing acute musculoskeletal conditions and are often used in tandem with rest and physical therapy. While muscle relaxers do not directly cause weight gain, they can lead to reduced physical activity, which may result in weight gain.
Muscle relaxers act on the central nervous system to reduce muscle tone and alleviate spasms. They can also relax blood vessels, decreasing vascular resistance and causing a decrease in blood pressure. These medications can affect your body in many ways besides reducing the spasms in your injured muscles. For instance, muscle relaxers can make people feel dizzy and sleepy, and some may even experience an allergic reaction.
Some muscle relaxers, such as cyclobenzaprine and baclofen, have anticholinergic effects. Anticholinergics block the action of acetylcholine, a neurotransmitter involved in muscle contraction and movement. This can lead to constipation, as the muscles in the gut relax, slowing down bowel movements. Anticholinergic medication can also cause a dry mouth, which is another common side effect of muscle relaxants.
While weight gain is not a common side effect of muscle relaxers, their sedative effects can reduce physical activity, potentially leading to weight gain. Older adults are at particular risk of experiencing weight gain due to the cognitive impairment caused by these medications. Short-term use of muscle relaxers can cause slight weight gain, typically around 2 to 3 lbs. Long-term use or abuse of these medications can lead to more significant weight gain as overall physical activity decreases.
It is important to note that muscle relaxers can have serious side effects, and their use should be carefully monitored, especially in older adults. If you have concerns about your weight or questions about whether medications you take could affect it, talk to your doctor.
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Frequently asked questions
Muscle relaxers are not known to directly cause weight gain. However, their sedative effects can lead to reduced physical activity, which may result in weight gain.
Muscle relaxers can have various side effects, including drowsiness, dizziness, constipation, impaired thinking, dry mouth, and itching. In older adults, these medications can lead to cognitive impairment, increasing the risk of significant weight gain.
Methocarbamol, a prescription muscle relaxant, has been linked to weight gain in some reports. However, it is important to note that skeletal muscle relaxants like cyclobenzaprine are generally not considered to directly affect weight.
Yes, muscle relaxers can lead to constipation, especially those with anticholinergic properties, as they slow down bowel movements. They can also cause hypotension by relaxing blood vessels and decreasing vascular resistance. Additionally, there is a risk of dependency and overdose with these medications.











































