Dominic Stone
Chlorpheniramine is an antihistamine medication used to treat symptoms such as runny nose, sneezing, itching, and watery eyes caused by allergies, the common cold, or the flu. It is typically taken as needed and comes in various forms, including tablets, capsules, liquids, and chewable tablets. While it is a common and effective medication, chlorpheniramine has been associated with certain side effects, such as drowsiness, excitability in children, and difficulty urinating. However, there is no explicit mention of muscle soreness as a direct side effect of chlorpheniramine in the sources provided. Nonetheless, it is always advisable to consult a doctor or pharmacist before taking any medication, especially if you have concerns about potential side effects or interactions with other substances.
| Characteristics | Values |
|---|---|
| Muscle soreness | No evidence found |
| Common side effects | Drowsiness, decreased sweating, excitability in children, inability to empty bladder, decreased breast milk production |
| Serious side effects | Allergic reactions, hives, difficulty breathing, swelling of face, lips, tongue, or throat |
| Precautions | Do not use if you have narrow-angle glaucoma, stomach or intestinal blockage, enlarged prostate, or asthma attack. Avoid alcohol, and do not drive or operate machinery until you know how it affects you. |
| Interactions | May interact with sleeping pills, narcotic pain medicine, muscle relaxers, anxiety medication, depression medication, seizure medication, and other antihistamines. |
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What You'll Learn
Chlorpheniramine side effects
Chlorpheniramine is an antihistamine that helps to relieve allergy symptoms. It is available over the counter (OTC) and is used to treat runny nose, sneezing, itching, and watery eyes caused by allergies, the common cold, or the flu.
Like all medicines, chlorpheniramine can cause side effects, but not everyone experiences them. The most common side effect is drowsiness, but it may cause excitability in some children. It can also affect your alertness or coordination. Therefore, it is advised not to drive or do other activities that require alertness or coordination until you know how chlorpheniramine affects you. Drinking alcohol while taking chlorpheniramine can increase the risk of drowsiness.
Chlorpheniramine may also cause serious side effects, including allergic reactions. Stop using chlorpheniramine and seek emergency medical help if you experience hives, difficulty breathing, or swelling of your face, lips, tongue, or throat. Other serious side effects include liver problems, bruising or bleeding more easily than normal, and anaphylaxis. Call your doctor or seek medical advice if you experience any of these side effects.
In addition, chlorpheniramine can decrease sweating, making you more prone to heat stroke. It may also interact with other medications, including sleeping pills, narcotic pain medicine, muscle relaxers, and medicines for anxiety, depression, or seizures. Therefore, it is important to consult your doctor or pharmacist before taking chlorpheniramine with other medications.
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Chlorpheniramine overdose
Chlorpheniramine is an antihistamine medication used to treat allergies, the common cold, or the flu. It is available over the counter and is typically well-tolerated, but it can cause side effects, particularly when taken in higher doses or in combination with certain other medications.
Overdose Effects
In the case of a chlorpheniramine overdose, the primary manifestation is central nervous system symptoms. It is important to note that the severity of symptoms may vary depending on the amount of medication taken and individual factors. While there have been no reported cases of rhabdomyolysis induced by acute chlorpheniramine poisoning alone, a case study reported a patient experiencing acute kidney injury and rhabdomyolysis after ingesting an extremely high dose of 4000 mg orally.
Combination with Other Medications
Chlorpheniramine may interact with other medications and increase the risk of adverse effects. Combining chlorpheniramine with dextromethorphan, for example, has been associated with serotonin toxicity in overdose. In one case, a patient presented to the emergency department after ingesting a large number of tablets containing both dextromethorphan and chlorpheniramine.
Precautions
It is crucial to take chlorpheniramine as directed by a healthcare provider and to avoid exceeding the recommended dosage. If you suspect an overdose, seek immediate medical attention by calling emergency services or a poison control center. Be sure to inform your healthcare provider about any other medications, vitamins, or supplements you are taking to prevent harmful drug interactions.
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Chlorpheniramine and alcohol
Chlorpheniramine is an antihistamine medication that helps to relieve symptoms of allergies, hay fever, and the common cold. It is available over the counter and comes in various forms, including tablets, capsules, chewable tablets, liquids, and extended-release formulations. It is typically taken as needed to alleviate symptoms such as a runny nose, sneezing, itching, and watery eyes.
When it comes to the interaction between chlorpheniramine and alcohol, it is important to exercise caution. Alcohol can increase the nervous system side effects of chlorpheniramine. This means that consuming alcohol while taking chlorpheniramine may lead to enhanced drowsiness, dizziness, and difficulty concentrating. In some individuals, alcohol may also exacerbate impairment in thinking and judgment.
To ensure safe use, it is recommended to avoid or limit alcohol consumption while being treated with chlorpheniramine. Patients should refrain from engaging in activities that require mental alertness or coordination, such as driving or operating hazardous machinery, until they understand how the medication affects them. It is crucial to follow the recommended dosage and not exceed it, as taking more chlorpheniramine than prescribed can further increase the risk of adverse effects.
Additionally, chlorpheniramine may interact with other medications and supplements. It is important to disclose to your healthcare provider any other substances you are taking, including prescription and over-the-counter medicines, vitamins, herbal products, and supplements. Certain drugs that cause sleepiness or slow breathing, such as sleeping pills, narcotic pain medications, muscle relaxants, or medicines for anxiety, depression, or seizures, may have additive effects when combined with chlorpheniramine and alcohol.
It is always advisable to consult your doctor or pharmacist if you have any questions or concerns about taking chlorpheniramine with alcohol or other substances. They can provide personalized guidance based on your medical history and ensure the safe and effective use of the medication.
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Chlorpheniramine and pregnancy
Chlorpheniramine is an antihistamine used to relieve symptoms of allergies, hay fever, and the common cold. It is available over the counter (OTC) and is sold under various brand names, including Chlor-Trimeton®, Aller-Chlor®, and Polaramine®.
Pregnancy
While chlorpheniramine is considered generally safe to take while pregnant, it is always recommended to consult with a healthcare provider before taking any medication during pregnancy. The US FDA has not assigned a pregnancy category for chlorpheniramine, and there are no controlled data available from human pregnancies. However, the Collaborative Perinatal Project monitored 1070 mother-child pairs with first-trimester exposure to chlorpheniramine and 3931 pairs with exposure at any time during pregnancy, and neither study suggested a relationship to major or minor malformations.
Most studies have found no increased chance of birth defects with the use of chlorpheniramine during pregnancy. However, two studies found a small increased chance for different types of birth defects, but no specific pattern has been reported. It is important to note that chlorpheniramine is not expected to increase the chance of other pregnancy-related problems such as preterm delivery or low birth weight.
Breastfeeding
Small (2 to 4 mg) and occasional doses of chlorpheniramine are considered acceptable while breastfeeding. However, larger doses or prolonged use might cause effects in the infant or decrease milk supply, especially when combined with sympathomimetics such as pseudoephedrine or before lactation is well established. Chlorpheniramine can cause sleepiness in adults, and this effect may also occur in nursing infants. Therefore, it is important to monitor the baby for any symptoms, such as drowsiness or irritability, and consult the child's healthcare provider if any concerns arise.
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Chlorpheniramine and breastfeeding
Chlorpheniramine is an antihistamine medication that treats symptoms like a runny nose, sneezing, itching, and watery eyes caused by allergies, the common cold, or the flu. It is available over the counter (OTC) and usually taken as needed.
According to Drugs.com, chlorpheniramine may pass into breast milk and may harm a nursing baby. Antihistamines may also slow breast milk production. Therefore, it is not recommended to take chlorpheniramine without first consulting a doctor if you are breastfeeding.
A study by the National Institute of Child Health and Human Development (2021) suggests that small (2 to 4 mg), occasional doses of chlorpheniramine are acceptable during breastfeeding. However, larger doses or more prolonged use might cause adverse effects in the infant or decrease milk supply, especially when combined with a sympathomimetic drug like pseudoephedrine or before lactation is well established. To minimise any effects of the drug on the infant, a single bedtime dose after the last feeding of the day is recommended for breastfeeding mothers. Nonsedating antihistamines are generally preferred alternatives during breastfeeding.
Precautions
Chlorpheniramine may cause serious side effects, including allergic reactions. It can also affect your alertness or coordination, so it is advised not to drive or perform activities requiring alertness until you know how chlorpheniramine affects you. Additionally, avoid becoming overheated or dehydrated during exercise or hot weather, as chlorpheniramine can decrease sweating, increasing the risk of heat stroke.
It is important to consult your doctor or pharmacist before taking chlorpheniramine with other medications, including prescription and over-the-counter drugs, vitamins, and herbal products. Alcohol consumption should also be avoided while taking chlorpheniramine as it may increase the risk of drowsiness.
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Frequently asked questions
Chlorpheniramine is an antihistamine used to treat symptoms of allergies, the common cold, or the flu, such as a runny nose, sneezing, itching, and watery eyes.
The most common side effect of chlorpheniramine is drowsiness. It may also cause excitability in some children. In rare cases, chlorpheniramine has been associated with dyskinesias and tremors, palpitations, tachycardia, arrhythmias, and hypotension.
Chlorpheniramine may cause serious allergic reactions, including hives, difficulty breathing, and swelling of the face, lips, tongue, or throat. It may also interact with certain medications and conditions, so it is important to consult a doctor or pharmacist before use.
Chlorpheniramine should not be used for longer than recommended, typically no more than 7 days in a row. It should be avoided by individuals with certain conditions, such as narrow-angle glaucoma, a blockage in the stomach or intestines, an enlarged prostate, or asthma. Pregnant and breastfeeding women should consult a doctor before taking chlorpheniramine.
Muscle soreness is not a known side effect of chlorpheniramine. However, it is important to consult a doctor or pharmacist to ensure it is safe for your specific circumstances.
