
Ciprofloxacin is a medicine that can cause several side effects, including muscle pain and weakness. It can also cause tendinitis or tendon rupture, which can lead to muscle pain and difficulty moving. This can occur during treatment or even months after stopping the medication. In some cases, ciprofloxacin may worsen muscle weakness in people with myasthenia gravis, a nervous system disorder. It is important to monitor for any signs or symptoms of muscle pain or other side effects while taking this medication and to consult a doctor if any adverse reactions occur.
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What You'll Learn
- Ciprofloxacin may cause inflammation or tearing of tendons (tendinitis)
- It can worsen muscle weakness in people with myasthenia gravis, a nervous system disorder
- Ciprofloxacin may cause peripheral neuropathy, a type of nerve damage that causes tingling, numbness, and pain
- It can cause severe stomach pain and diarrhea
- Ciprofloxacin may increase the risk of an aortic aneurysm

Ciprofloxacin may cause inflammation or tearing of tendons (tendinitis)
Ciprofloxacin is a medicine that can cause side effects, although not everyone experiences them. One such side effect is inflammation or tearing of tendons, known as tendinitis. Tendinitis can cause pain, swelling, tenderness, stiffness, or difficulty moving a muscle. It can occur in tendons in the shoulder, hand, back of the ankle, or other body parts.
The risk of developing tendinitis is higher for people over 60 years old, those using steroid medications, those with severe kidney problems, a history of tendon problems, or a history of organ transplants. People with myasthenia gravis, a nervous system disorder that causes muscle weakness, should also be cautious when taking ciprofloxacin as it may worsen their condition.
If you experience any symptoms of tendinitis while taking ciprofloxacin, it is important to stop taking the medication, rest, and seek medical advice from your doctor immediately. Tendinitis can lead to tendon rupture if left untreated, which may cause permanent damage.
It is always advisable to speak to a doctor or pharmacist if you have any concerns about your medication or experience any unusual symptoms. They will be able to provide personalized advice and guidance based on your medical history and the specifics of your medication.
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It can worsen muscle weakness in people with myasthenia gravis, a nervous system disorder
Ciprofloxacin is a fluoroquinolone antibiotic. Fluoroquinolones are associated with prolonged (up to months or years), serious, disabling and potentially irreversible drug reactions affecting several, sometimes multiple, systems, organs, and senses.
Ciprofloxacin can cause muscle pain and weakness. This can occur in the first two days of taking the medication or even several months after stopping. It is more common in children. In one case, a 58-year-old male developed fulminating musculoskeletal pain associated with third-time exposure to ciprofloxacin. The symptoms completely disappeared 24 hours after discontinuing the medication.
People with myasthenia gravis, a nervous system disorder, are at particular risk of muscle weakness from ciprofloxacin. Myasthenia gravis is a disorder of the nervous system that causes muscle weakness. Taking ciprofloxacin may worsen muscle weakness in people with myasthenia gravis and cause severe difficulty breathing or even death. If you have myasthenia gravis, your doctor may advise against taking ciprofloxacin. If they do prescribe ciprofloxacin, you should call your doctor immediately if you experience muscle weakness or difficulty breathing during treatment.
If you experience any symptoms of tendinitis, such as pain, swelling, tenderness, stiffness, or difficulty moving a muscle, stop taking ciprofloxacin and call your doctor immediately. Tendon rupture is also a risk, and if you experience any symptoms of tendon rupture, such as hearing or feeling a snap or pop in a tendon area, or an inability to move or bear weight on an affected area, stop taking ciprofloxacin and seek emergency medical treatment.
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Ciprofloxacin may cause peripheral neuropathy, a type of nerve damage that causes tingling, numbness, and pain
Ciprofloxacin is a medicine that can cause side effects, although not everyone experiences them. One of the rare but serious side effects of taking ciprofloxacin is peripheral neuropathy, a type of nerve damage that causes tingling, numbness, and pain. This nerve damage can occur soon after starting the medication and may not go away even after stopping.
Peripheral neuropathy typically affects the hands and feet, causing symptoms such as numbness, tingling, pain, burning, or weakness. If you experience any of these symptoms, it is important to stop taking ciprofloxacin and seek medical advice from your doctor immediately.
The risk of developing peripheral neuropathy may be higher in individuals with certain risk factors. For example, those with myasthenia gravis, a nervous system disorder that causes muscle weakness, may experience worsened muscle weakness and severe difficulty breathing when taking ciprofloxacin. It is crucial to inform your doctor if you have myasthenia gravis before taking this medication.
Additionally, ciprofloxacin has been associated with tendinitis (inflammation of a tendon) and tendon rupture (tearing of a tendon). Tendon problems can occur during treatment or even months after stopping the medication. The risk of tendon issues is higher in older individuals, those with kidney problems, and those who have had organ transplants. It is important to be vigilant for signs and symptoms of tendonitis or tendon rupture, such as sudden pain or swelling in a tendon, bruising, or difficulty moving or bearing weight on the affected area. If any of these symptoms occur, it is imperative to stop taking ciprofloxacin and seek medical attention.
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It can cause severe stomach pain and diarrhea
Ciprofloxacin is a medicine that can cause side effects, including severe stomach pain and diarrhoea. It is important to be aware of these potential side effects and to know what to do if they occur.
Stomach pain and diarrhoea are both recognised side effects of taking ciprofloxacin. While these symptoms can be mild and temporary, they can also become more serious and persist for a long time. For example, diarrhoea may occur two months or more after stopping the medication. It is important to drink plenty of fluids if you experience diarrhoea, as this can lead to dehydration. In addition, if you are taking the contraceptive pill, be aware that severe diarrhoea for more than 24 hours may affect the effectiveness of your contraception.
If you experience severe stomach pain or diarrhoea while taking ciprofloxacin, it is important to seek medical advice. Check with your doctor as soon as possible, as these may be symptoms of a more serious condition, such as a liver problem. In some cases, ciprofloxacin may also cause nerve damage, which can lead to numbness, tingling, pain, burning, or weakness in the arms and legs. This damage may occur soon after starting the medication and may not go away even after stopping. Therefore, it is important to report any suspected side effects and to seek medical attention if necessary.
People with certain conditions or taking certain medications may be at a higher risk of experiencing side effects from ciprofloxacin. For example, those with myasthenia gravis, a nervous system disorder that causes muscle weakness, may experience severe muscle weakness or difficulty breathing if they take ciprofloxacin. In addition, those over 60 years old, with kidney problems, or who have received an organ transplant may be more prone to joint pain, swelling, and tendon damage. It is important to speak to your doctor about any relevant medical history before taking ciprofloxacin.
To minimise the risk of side effects, it is important to take ciprofloxacin as directed by your doctor. Do not take more or less than the recommended dose, and do not stop taking it without consulting your doctor first. It may also help to take the medication with food or a snack and to avoid rich or spicy foods while taking ciprofloxacin. If you experience any unusual or persistent side effects, be sure to report them to your doctor or pharmacist.
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Ciprofloxacin may increase the risk of an aortic aneurysm
Ciprofloxacin is an antibiotic medication that can cause several side effects, including muscle pain and weakness. While muscle pain and weakness are common side effects, they can sometimes indicate more serious underlying conditions.
Research has shown that the use of fluoroquinolone antibiotics, including ciprofloxacin, is associated with an increased risk of aortic aneurysm formation. This risk is particularly elevated in individuals over the age of 65, with some studies reporting a more than double increase in risk within 30-60 days of taking the medication. The risk remains high for up to 365 days after taking fluoroquinolones.
Additionally, the duration of ciprofloxacin use has been found to be a significant factor in the development and severity of aortic aneurysms. In a rat model study, it was observed that increasing the duration of ciprofloxacin administration led to a significant increase in aortic diameter, indicating the progression of an aneurysm. This study also demonstrated that ciprofloxacin caused injury to the aortic wall, further supporting the link between the medication and aortic aneurysm development.
It is important for individuals taking ciprofloxacin to be aware of the signs and symptoms of an aortic aneurysm. If you experience sudden, severe, and constant pain in the stomach, chest, or back, seek immediate medical attention. Other warning signs may include difficulty breathing, a cough, or hoarseness.
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Frequently asked questions
Yes, ciprofloxacin can cause muscle pain and weakness. In rare cases, it may cause acute severe myalgia, which requires emergency care treatment.
If you experience muscle pain after taking ciprofloxacin, you should stop taking the medication and contact your doctor immediately.
Other side effects of ciprofloxacin include:
- Diarrhea
- Nausea
- Sensitivity to sunlight
- Tendonitis
- Tendon rupture
- Neuropathy
- Confusion
- Difficulty sleeping


























