
Ehlers-Danlos Syndrome (EDS) is a genetic condition that affects the body's connective tissue, causing hypermobile joints and fragile skin. While there is no cure for EDS, physical therapy and muscle-strengthening exercises are often recommended to help manage symptoms and improve joint stability. This raises the question: does EDS affect muscle retention and growth? Research suggests that EDS patients can benefit from resistance training, which increases tendon stiffness and improves muscle strength and function. However, building muscle can be challenging due to associated symptoms such as fatigue, muscle spasms, and pain. Proper nutrition, including adequate protein intake, is also crucial for muscle recovery and growth in individuals with EDS.
| Characteristics | Values |
|---|---|
| Muscle function | Affected by connective tissue distensibility |
| Muscle weakness | Generalized muscle weakness is characteristic of the disease |
| Muscle spasms | Eliminating or minimizing muscle spasms is often the first step in reducing pain |
| Muscle soreness | Uncomfortable muscle soreness after exercise may be due to a lack of protein |
| Muscle strength | Progressive resistance training 3 days a week for 4 months increased mean isometric leg extension force and leg extensor power by 8% and 11% respectively |
| Muscle recovery | Good nutrition, including protein, vitamin C, zinc, manganese, and copper, can help the body recover from exercise |
| Muscle-building exercises | Muscle-building exercises can help strengthen muscles around hypermobile joints, increasing joint stability and decreasing symptoms like muscle spasms and pain |
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What You'll Learn

Muscle-building exercises
However, building muscle can be challenging for people with EDS due to problems like fatigue, post-exertional malaise, and intense delayed-onset muscle soreness. It is important to note that high-skill movements, such as backflips, may introduce a greater risk of injury and may not be the most efficient way to build muscle. Instead, focus on stable exercises that target specific muscle groups.
- Basic level mat Pilates: Modified for a clinical population, these exercises can help build core strength, improve proprioception and body awareness, and enhance motor control.
- Resistance training: This type of training creates microtears in the muscle fibers, stimulating muscle growth during the healing process. However, ensure you are consuming adequate protein to support muscle repair and growth.
- Slow and controlled weight training: By moving weights slowly through a joint's range of motion, you can improve fine motor control and force the muscles to exert precise control over the joint's position. This method also makes lighter weights effective for achieving muscular fatigue without the need for heavy lifting, which is not recommended for people with EDS.
- Cardiorespiratory exercise: Also known as cardiovascular exercise, this type of activity gets the heart and lungs pumping and transfers oxygen to the muscles. Examples include walking, swimming, using a treadmill or exercise bike, and cross-training. Aim for 150 minutes of moderate-intensity exercise per week, broken down into smaller chunks if needed.
- Physical therapy: Working with a physiotherapist can help strengthen the muscles around your joints and improve joint stability.
It is important to prioritize stable exercises that are safe and effective for your specific goals and conditions. Consult with a healthcare professional or trained instructor to ensure that your exercise routine is tailored to your needs and performed correctly.
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Nutritional requirements
While there is no cure for Ehlers-Danlos Syndrome (EDS), nutritional requirements, along with muscle and connective tissue-strengthening exercises, can help patients manage their symptoms and improve their quality of life.
Protein is needed for muscle growth and repairing damaged cells and tissues in the body. Exercise, especially resistance training, creates small tears in the muscles, and these microtears stimulate muscle growth through the healing process. For the body to heal and for the muscle to grow, the right amount of amino acids from protein in food is required. However, many people with EDS do not meet their body's protein needs due to fatigue, chronic nausea, or multiple dietary restrictions. Increasing protein intake can help with symptoms such as lethargy, delayed healing, and weak muscles. Good sources of protein include whole milk, whole yogurt, peanut butter, almond butter, olive oil, and coconut flakes.
Vitamin C is required for collagen synthesis, which is necessary for tendons and ligaments to heal. Recommended intake for healthy adults is 75-90mg of vitamin C daily, which can be sourced from most fruits and vegetables, including strawberries, kiwi, potatoes, raw bell peppers, raw tomatoes, and raw broccoli. Copper also plays a role in collagen production by activating an enzyme called lysyl oxidase, which is required for collagen maturation. Recommended intake for healthy adults is 900 micrograms of copper, which can be sourced from dark chocolate, cashews, oysters, and sunflower seeds.
Other nutritional recommendations for people with EDS include staying hydrated, eating small portions throughout the day, and choosing ancient whole grains instead of refined grains.
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Joint hypermobility
While some people with hypermobile joints do not experience any pain or medical issues, for others, hypermobility causes joint pain, joint and ligament injuries, fatigue, bowel issues, and other symptoms. JHS can also be a sign of a more serious underlying genetic condition, such as Heritable Disorders of Connective Tissue (HDCT). Rare medical conditions associated with JHS include Ehlers-Danlos syndrome, Marfan syndrome, and Down syndrome.
Ehlers-Danlos syndrome (EDS) is a group of conditions that affect cartilage, bone, fat, and blood. It is caused by a defect in collagen, the protein that adds flexibility and strength to connective tissue. EDS can affect the mouth and jaw structures, with symptoms such as an overly moveable jaw joint, clicking, grinding, and permanent locking of the jaw.
Managing JHS symptoms can be done through improving muscle strength and fitness to better protect the joints. This can be achieved through gentle, low-impact exercises such as swimming or cycling, as well as strengthening the muscles around the hypermobile joints. Proper nutrition, including protein, vitamin C, zinc, manganese, and copper, is also important for recovery and building muscle strength.
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Muscle soreness
EDS patients often experience muscle pain and soreness due to the underlying connective tissue disorder. This can be managed through physical therapy and targeted exercises to strengthen the muscles around the joints, improving joint stability and reducing muscle spasms and pain.
To alleviate muscle soreness, EDS patients are advised to focus on strengthening exercises that create microtears in the muscle fibers, stimulating muscle growth and repair. This can include resistance training, which has been shown to be effective in improving tendon and skeletal muscle properties in EDS patients. Additionally, proper nutrition, including adequate protein intake, is crucial for muscle recovery and growth, as protein provides the amino acids necessary for repairing damaged cells and tissues.
It is important to note that high-skill movements, such as backflips, may not be the best choice for EDS patients as they introduce a significant risk of injury. Instead, exercises like wall sits, squats, and progressive resistance training targeting specific muscle groups are recommended as they efficiently strengthen muscles without requiring advanced skills.
By combining appropriate nutrition with muscle-strengthening exercises, EDS patients can actively support their bodies and work towards feeling better and improving their overall muscle health.
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Muscle spasms
To manage muscle spasms, physiotherapy can be beneficial. Physiotherapists can design specific exercise regimens to help patients gain strength, improve mobility, and increase their range of motion while strengthening joints prone to dislocation. Additionally, a knowledgeable therapist can provide advice and tools to manage painful spasms at home. Lifestyle changes, such as altering chewing patterns, diet, and stress reduction techniques, can also help minimise muscle spasms.
In terms of nutrition, ensuring adequate intake of energy, protein, vitamin C, zinc, manganese, and copper is essential for recovery from exercise and building muscle resilience. Protein, in particular, is crucial for repairing damaged cells and tissues, as it provides the necessary amino acids for the body to heal. However, many EDS patients struggle to meet their protein requirements due to fatigue, chronic nausea, or dietary restrictions.
While strengthening the muscles around hypermobile joints is recommended, it can be challenging for EDS patients due to associated symptoms such as fatigue, post-exertional malaise, and intense muscle soreness. Nevertheless, with proper nutritional support, physiotherapy, and lifestyle changes, managing muscle spasms and improving overall muscle health in EDS patients is achievable.
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Frequently asked questions
Ehlers-Danlos Syndrome (EDS) is a genetic condition that affects the body's ability to produce collagen, which supports connective tissue. It commonly affects the skin and joints, causing them to be weaker and more flexible than usual.
EDS causes muscle weakness and joint hypermobility, which can make muscle-building exercises challenging. However, muscle strength can be improved through resistance training, which creates microtears in the muscle fibres that stimulate growth during the healing process.
Exercises that focus on strengthening the muscles around the joints are recommended for people with EDS. Physical therapy, progressive resistance training, and simple exercises like wall sits can help improve muscle strength and joint stability while reducing the risk of injury.











































