
Muscle pain, or myalgia, has many causes and is usually temporary and not serious. However, chronic inflammation in the muscles, known as myositis, can lead to muscle weakness, swelling, and pain. Myositis is caused by the immune system attacking muscles, resulting in inflammation that comes and goes over time. Polymyositis is a type of myositis that causes muscles to become irritated and inflamed, eventually leading to weakness and difficulty with movement. Viral infections and bacterial infections can also trigger inflammation throughout the body, including in the muscles. Inflammation in the muscles can be treated with anti-inflammatory drugs such as NSAIDs (nonsteroidal anti-inflammatory drugs) and steroid medications.
| Characteristics | Values |
|---|---|
| Myalgia | Muscle pain that is usually temporary and not serious |
| Myositis | A group of conditions that cause inflammation in muscles |
| Polymyositis | A disease that causes muscles to become irritated and <co: 8,9,11,12,15>inflamed |
| Viral infections | Can trigger inflammation throughout the body |
| Treatment for inflammation | Nonsteroidal anti-inflammatory drugs (NSAIDs) like aspirin and ibuprofen |
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What You'll Learn

Viral and bacterial infections
Muscle soreness and inflammation have a wide range of causes, from injury and overuse to chronic diseases. Viral and bacterial infections can also trigger inflammation throughout the body, leading to muscle pain and soreness.
Myositis, an inflammatory condition, is one example of a disease caused by viral and bacterial infections that can result in muscle soreness. It is characterized by chronic inflammation of the muscles, leading to pain, tenderness, swelling, and weakness. The condition can be caused by a variety of pathogens, including bacteria, viruses, fungi, and parasites. However, viral infections are the most common infectious cause of myositis, with bacteria being a rare trigger. Viruses or bacteria can directly attack muscle tissue or release substances that damage muscle fibers. Common cold and flu viruses, as well as HIV, have been linked to myositis.
In addition to myositis, other viral infections such as hepatitis have been associated with musculoskeletal syndromes. Vaccines, which simulate viral infections, can also cause muscle pain as a side effect. Bacterial infections, while less common, can lead to acute rhabdomyolysis, a serious complication that can result in permanent kidney damage.
The treatment for myositis depends on its cause. Viral infections often do not require specific treatment, while bacterial infections typically respond to antibiotics. Immunosuppressive agents and anti-inflammatory medications are also used to manage myositis symptoms and reduce inflammation. Physical therapy, including stretching and strengthening exercises, is an important part of myositis management, helping to ease pain and stiffness.
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Overuse and strain
Muscle soreness and pain, also known as myalgia, can be caused by overuse and strain. This can occur when a person repeats the same movement over and over, whether at work or during recreational activities, eventually straining the muscles. This is known as a repetitive strain injury. Overtraining without letting the muscles rest can also lead to overuse and strain, as it weakens the muscles, making them more susceptible to breakage.
Muscle strains, or pulled muscles, are common injuries that occur when a person overstretches or tears a muscle or a tendon. They can range from mild to severe, with a grade 1 strain only pulling and breaking a few fibres, and a grade 3 strain tearing the muscle completely. These tears in the muscle fibres can cause bleeding or bruising and are often painful.
Sitting for long periods, such as at a desk job, can also cause muscle stiffness and pain. This is a form of overuse or underuse, where certain muscles are used less than others, leading to imbalances and soreness.
To treat muscle soreness caused by overuse and strain, rest is crucial to allow the tears in the muscle fibres to heal. Gentle stretching can also help prevent stiffness and maintain flexibility during the recovery process. Massage is another effective treatment, as it relieves tension and improves blood flow to the affected area. For acute pain, cold therapy can be applied to reduce inflammation and swelling.
While muscle soreness due to overuse and strain is typically temporary and not severe, chronic muscle inflammation can occur in cases such as myositis, where the immune system attacks the muscles. This can cause recurring episodes of muscle pain and weakness over an extended period.
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Myositis
The disease is caused by the body's immune system attacking its own muscle fibres, leading to muscle damage and weakness. This process is known as necrosis, where muscle cells start to die. The exact cause of myositis is unknown, but it is believed to be triggered by various factors, including infections, injuries, autoimmune conditions, or drug side effects. Viral infections, such as the common cold, flu, and HIV, are common infectious causes. Intense exercise can also lead to muscle inflammation, which is considered a mild form of myositis that usually resolves with rest.
Diagnosing myositis can be challenging due to its rarity and varied symptoms. The process typically involves a medical history review, physical examination, blood tests, muscle and skin biopsies, and other diagnostic tests. Treatment focuses on managing symptoms through medications such as corticosteroids and immunosuppressants, as well as physical therapy and exercises to improve muscle strength and flexibility.
While there is no cure for myositis, proper treatment can help manage the condition and prevent serious complications. Early diagnosis and intervention are crucial to improve long-term outcomes and maintain quality of life for those living with myositis.
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Polymyositis
The symptoms of polymyositis include severe muscle weakness, trouble swallowing, difficulty speaking, and shortness of breath. It can also cause weight loss and malnutrition due to the difficulty in chewing and swallowing. The condition develops gradually over weeks or months, and by the time symptoms appear, individuals may have already lost about half of their muscle fibers.
There is currently no cure for polymyositis, but treatments are available to manage the symptoms and reduce their impact on daily life. Common treatments include corticosteroids, which help reduce inflammation and ease pain, and immunosuppressant medications, which suppress the immune system's attack on the body's tissues. Physical therapy and exercises are also recommended to maintain muscle flexibility and strength.
Healthcare providers use various tests to diagnose polymyositis and rule out other conditions with similar symptoms. These tests include blood tests, MRI scans, EMG, and muscle biopsies. While there is no known prevention for polymyositis, early diagnosis and treatment are crucial to avoid severe complications and improve the chances of managing the condition effectively.
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Anti-inflammatory drugs
Inflammation can indeed cause sore muscles. Viral and bacterial infections can trigger inflammation throughout the body, and blunt force trauma can cause muscle contusions and strains. Myositis is another example of a disease that causes chronic inflammation in the muscles.
Non-steroidal anti-inflammatory drugs (NSAIDs) are a common treatment for muscle soreness and injuries. NSAIDs help reduce inflammation, swelling, and fever, as well as relieve pain. Common NSAIDs include aspirin, ibuprofen, and naproxen sodium, which are available over the counter. NSAIDs are typically used to treat acute injuries caused by sudden impact, such as collisions or falls, and are most effective when taken immediately after an injury, before swelling occurs.
While NSAIDs can be effective in reducing muscle pain and soreness, there are several drawbacks and side effects to consider. NSAIDs are meant for short-term and immediate treatment and are not recommended for long-term use or before or during endurance sports. Studies have shown that NSAIDs may mask pain, leading to an increased risk of injury, and can interfere with the muscle-building process, depriving athletes of the full training benefits of their workouts. Additionally, NSAIDs can cause gastrointestinal issues, such as stomach upset, mild headaches, and balance issues. In rare cases, more severe side effects may occur, including unusual weight gain, blurred vision, and photosensitivity.
If you are experiencing muscle pain or soreness, it is important to consult with a healthcare professional to determine the best course of treatment. Self-care options for everyday muscle aches and pains include rest, gentle stretching, massage, and cold therapy.
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Frequently asked questions
Myalgia means muscle pain and has many causes. It is usually temporary and not serious, but some chronic diseases can cause ongoing, widespread myalgia.
Muscle inflammation, or myositis, can be caused by viral infections, bacterial infections, injury, autoimmune conditions, or drug side effects. Myositis is a rare condition that causes muscle weakness, tiredness, and pain.
The symptoms of myositis vary between individuals but can include muscle weakness, tiredness, and pain, as well as a skin rash. Myositis can affect the muscles used for breathing and swallowing, so it is important to seek medical attention if you experience difficulty in these areas.
There is currently no cure for myositis, but treatments can help manage symptoms. These include steroid medicines, immunosuppressants, intravenous immunoglobulin, and physical therapy exercises.
Yes, inflammation can cause sore muscles. This can be due to myositis, as well as other conditions such as viral or bacterial infections, repetitive strain injuries, or overuse of muscles.







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