
Montelukast is a daily oral medication used to prevent asthma attacks, exercise-induced bronchoconstriction, and allergy symptoms in both adults and children. It is also used to treat allergic rhinitis (hay fever) and prevent wheezing, coughing, and chest tightness caused by asthma. While it is a useful medication, it can cause some unwanted side effects, including muscle pain and cramping. This paragraph will explore whether montelukast causes muscle pain and provide an overview of other associated side effects.
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What You'll Learn
- Montelukast's side effects include muscle pain, cramping, and sleep problems
- The medicine may cause serious mental health changes, including suicidal thoughts
- It can also lead to blood vessel inflammation, with flu-like symptoms and rash
- Other side effects include stomach discomfort, unusual dreams, and increased bleeding tendency
- Headaches are common but usually subside after the first week of taking montelukast

Montelukast's side effects include muscle pain, cramping, and sleep problems
Montelukast is a daily oral medication used to prevent asthma attacks, exercise-induced bronchoconstriction, and allergy symptoms in adults and children. It is also used to treat seasonal or perennial allergic rhinitis (hay fever). While montelukast can be beneficial for managing these conditions, it is important to be aware of its potential side effects, which can vary from person to person.
One of the known side effects of montelukast is muscle pain and cramping. This drug can cause muscle aching and cramping, as reported by some users. If you experience these symptoms, it is important to consult your healthcare provider for advice and to explore possible alternatives or treatments.
In addition to muscle pain, montelukast has also been associated with sleep problems in some individuals. Sleep disturbances, including insomnia and unusual dreams, have been reported by patients taking montelukast. If you experience sleep difficulties while taking this medication, it is recommended to discuss it with your doctor. They may provide suggestions to mitigate these issues or consider alternative treatments.
It is worth noting that the side effects of montelukast can vary in severity and may be mild or serious. Some people may experience mood changes, agitation, aggression, depression, confusion, or even suicidal thoughts. These behavioural and mental health changes can occur during treatment or even after stopping the medication. Therefore, it is crucial to monitor any changes in mood or behaviour and seek medical advice if you or your loved ones notice any unusual symptoms.
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The medicine may cause serious mental health changes, including suicidal thoughts
Montelukast is a leukotriene receptor antagonist approved for asthma and allergies. It is usually taken once a day and is available as a tablet, a chewable tablet, and granules to take by mouth. While it is a prescription medication approved by the FDA, it has been associated with serious mental health changes, including suicidal thoughts and actions.
In 2018, approximately 9.3 million patients of any age received a prescription for montelukast from U.S. outpatient retail pharmacies, with 2.3 million being children under 17. The FDA has since strengthened its warning about the serious mental health side effects of the drug, requiring a boxed warning—the agency's most prominent. The boxed warning will describe these serious mental health side effects and recommend that montelukast be reserved to treat allergic rhinitis only in patients who cannot be treated with alternative therapies.
The FDA has identified 82 cases of completed suicide associated with montelukast. Many cases reported the development of concomitant neuropsychiatric symptoms prior to the event. Patients taking montelukast who exhibit mood-changing behaviours should immediately report symptoms to a healthcare provider. These symptoms may include agitation, aggressive behaviour, anxiety, irritability, difficulty paying attention, confusion, unusual dreams, hallucinations, depression, difficulty falling asleep or staying asleep, restlessness, sleepwalking, suicidal thoughts or actions, or tremors.
It is important to note that these mental health side effects can occur while taking the medication or even after treatment has stopped. If you or someone you know is taking montelukast and experiencing any of these symptoms, they should stop taking the medication and contact a healthcare professional immediately.
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It can also lead to blood vessel inflammation, with flu-like symptoms and rash
Montelukast is a daily oral medication used to prevent asthma attacks, exercise-induced bronchoconstriction, and allergy symptoms in adults and children. While it is a useful medication, it can also lead to some side effects, including blood vessel inflammation, which presents as flu-like symptoms, a rash, and a pins-and-needles feeling in the arms and legs.
Blood vessel inflammation, or vasculitis, is a rare but serious side effect of taking montelukast. It can cause swelling throughout the blood vessels and is known as Churg-Strauss syndrome. This usually occurs in patients who have asthma or are taking oral steroid medications that are being stopped or reduced in dosage.
The flu-like symptoms associated with blood vessel inflammation can include fever, chills, body aches, and fatigue. These symptoms may be mild or severe and should be assessed by a medical professional. It is important to note that not all side effects require medical attention, as some may go away during treatment as the body adjusts to the medication.
The rash that can occur with blood vessel inflammation may be mild or severe. Severe rashes can be a sign of Stevens-Johnson syndrome, a serious and potentially life-threatening condition that requires immediate medical attention.
If you experience any signs of blood vessel inflammation, including flu-like symptoms, a rash, or a pins-and-needles sensation in your arms or legs, it is important to stop taking montelukast and contact your doctor right away. They can provide advice and guidance on managing these side effects and determining if the benefits of the medication outweigh the risks for your particular case.
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Other side effects include stomach discomfort, unusual dreams, and increased bleeding tendency
Montelukast is a prescription medicine for asthma and allergies. It has been associated with a range of side effects, including stomach discomfort, unusual dreams, and increased bleeding tendencies.
Stomach discomfort is a known side effect of montelukast. Patients taking this medication have reported stomach pain, nausea, and other gastrointestinal issues. These symptoms can range from mild to severe and may be persistent or intermittent. It is important for patients experiencing stomach discomfort to consult their doctor, as it could indicate a more serious issue.
Unusual dreams are another potential side effect of montelukast. Some patients have reported experiencing vivid dreams, nightmares, or other unusual dream-related phenomena while taking this medication. While these dreams may not be harmful, they can be disruptive to sleep and cause fatigue or drowsiness during the day. Patients who experience unusual dreams should discuss them with their doctor, as they may be indicative of underlying sleep disturbances or other issues.
Additionally, montelukast may increase the risk of bleeding. This side effect is particularly concerning for patients with underlying bleeding disorders or those taking other medications that affect blood clotting. Patients taking montelukast may bruise more easily, experience longer bleeding times, or have difficulty stopping bleeding from minor cuts or injuries. Any unusual bleeding should be reported to a doctor immediately, as it could indicate a serious medical issue.
It is important to note that while these side effects have been reported with montelukast use, they may not occur in all individuals. The benefits of taking montelukast for asthma or allergies may outweigh the risks for some patients. However, due to the potential for serious side effects, it is crucial to consult a healthcare professional before starting this medication and to report any new or unusual symptoms promptly.
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Headaches are common but usually subside after the first week of taking montelukast
Montelukast is a medication used to prevent asthma attacks, exercise-induced bronchoconstriction, and allergy symptoms in adults and children. It is typically well-tolerated, but like all medications, it can cause side effects in some people.
Headaches are one of the most common side effects of montelukast, occurring in more than 1 in 100 people. However, these headaches usually subside within the first week of taking the medication. It is important to note that if headaches persist beyond the first week or become severe, it is recommended to consult a doctor.
The exact mechanism behind montelukast-induced headaches is not fully understood. However, it is believed that they may be related to the drug's effect on blood vessels and neurotransmitters in the brain. Some people may also experience other side effects along with headaches, such as sleep disturbances, mood changes, or stomach discomfort.
It is worth noting that while headaches are common during the first week of montelukast treatment, they should not be ignored. If the headaches persist or interfere with daily activities, it is advisable to speak to a healthcare professional. They may provide advice on managing the headaches or adjust the dosage or medication if necessary.
Additionally, it is important to be aware of other, less common but more serious side effects of montelukast. These include serious neuropsychiatric events, such as agitation, aggression, depression, sleep disturbances, and even suicidal thoughts or behaviour. These side effects are not common but can be dangerous, and it is crucial to seek immediate medical attention if they occur.
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Frequently asked questions
Montelukast is a daily oral medication used to prevent asthma attacks, exercise-induced bronchoconstriction, and allergy symptoms in adults and children.
Like all medicines, montelukast can cause side effects, although not everyone gets them. Some common side effects include headaches, stomach discomfort, unusual dreams, muscle aching or cramping, swollen joints, and sleep problems. Serious neuropsychiatric events have also been reported in some patients.
Yes, muscle aching or cramping is listed as a possible side effect of montelukast.
If you experience muscle pain or other side effects that are concerning or bothersome, speak to your pharmacist or doctor. They can give you tips on how to manage these side effects.
Yes, call your doctor right away or seek emergency medical assistance if you experience serious side effects such as signs of blood vessel inflammation (flu-like symptoms, severe sinus pain, rash, numbness, or a "pins and needles" feeling in your arms or legs), serious changes in mood or behaviour, or severe allergic reactions (anaphylaxis).



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