
Prednisone is a medicine that is available as a tablet, delayed-release tablet, solution (liquid), and concentrated solution to be taken by mouth. It is usually taken with food one to four times a day or once every other day. Prednisone may cause muscle pain and weakness as a side effect. It can also cause steroid-induced myopathy, which is a toxic non-inflammatory myopathy caused by exogenous corticosteroid administration. This condition typically develops with doses higher than 10 mg prednisone equivalents per day for four weeks or longer. It is important to consult a doctor before stopping the medication as suddenly stopping prednisone can cause extreme tiredness, weakness, slowed movements, upset stomach, weight loss, changes in skin colour, sores in the mouth, and craving for salt.
| Characteristics | Values |
|---|---|
| Forms | tablet, delayed-release tablet, solution (liquid), concentrated solution |
| Dosage | One to four times a day or once every other day |
| Side effects | Increased infections, thinning of bones (osteoporosis), slowed growth in children, increased risk of cancer, upset stomach, weight loss, changes in skin color, mouth sores, extreme tiredness, weakness, slowed movements, craving for salt, muscle pain or weakness, muscle cramps, changes in heart rate, blurred vision, eye pain, difficulty in reading |
| Precautions | Avoid people who are sick, wash hands frequently, avoid people with chickenpox or measles, do not take with other medicines without consulting a doctor, do not stop taking without consulting a doctor, do not take more or less than the prescribed amount, do not take for longer than prescribed, do not crush, break or chew delayed-release tablet, store at room temperature away from heat, moisture and direct light, keep out of reach of children |
| Treatment | Prescriber may recommend reducing dose, stopping medication, applying hot or cold compress, over-the-counter pain relievers, physical therapy |
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What You'll Learn

Prednisone causes muscle pain and weakness
Oral steroids such as prednisone can cause muscle pain and weakness. Prednisone is usually taken with food one to four times a day or once every other day. The dosage is dependent on the patient's condition and response to treatment. It is important to follow the directions on the prescription label and not to take more or less than the prescribed amount.
Prednisone is a corticosteroid, and long-term use of corticosteroids can lead to a condition called corticosteroid-induced myopathy, which is a toxic noninflammatory myopathy caused by exogenous corticosteroid administration. This condition typically develops with prednisone doses higher than 10 mg/day for four weeks or longer. Elderly patients are at a higher risk of developing corticosteroid-induced myopathy due to their lower baseline muscle mass.
Symptoms of corticosteroid-induced myopathy include muscle weakness and pain. This condition is often reversible, with improvement typically occurring within 3 to 4 weeks of tapering off the steroids. However, recovery can take up to a year. Treatment options include switching to non-fluorinated glucocorticoids, such as dexamethasone or hydrocortisone, or alternate-day dosing. Physical therapy, in the form of resistance and aerobic exercise, has also been shown to be effective in preventing and treating corticosteroid-induced myopathy.
It is important to note that prednisone may also cause other side effects, such as an increased risk of infection, thinning of the bones (osteoporosis), and slowed growth in children. Therefore, it is crucial to discuss the risks and benefits of taking prednisone with a doctor and to report any unusual symptoms.
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Prednisone is an oral steroid
Prednisone is a corticosteroid, a group of medications that work on the immune system to help relieve swelling, redness, itching, and allergic reactions. It decreases inflammation, slows an overactive immune system, or replaces cortisol. Cortisol is a hormone that helps the body respond to stress, injury, and illness.
As a steroid, prednisone may decrease your ability to fight infection and may prevent you from developing symptoms if you get an infection. Therefore, it is important to avoid people who are sick and to wash your hands often while taking this medication. It is also important to avoid people with chickenpox or measles and to inform your doctor immediately if you think you have been exposed.
Additionally, prednisone may cause side effects such as thinning of the bones (osteoporosis), slowed growth and development in children, increased risk of certain types of cancer, changes in mood or behaviour, and muscle pain or weakness. It is important to follow the directions on your prescription label and not to stop taking prednisone without first consulting your doctor, as suddenly discontinuing the medication can cause symptoms such as extreme tiredness, weakness, and upset stomach.
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Prednisone may cause osteoporosis
Prednisone is a corticosteroid medication that is used to treat a range of conditions, including joint or muscle pain, breathing or intestinal ailments, and certain types of pneumonia in patients with acquired immunodeficiency syndrome (AIDS). While prednisone can be effective in managing these conditions, long-term use of this medication may lead to a serious side effect: osteoporosis.
Osteoporosis is a condition characterized by a loss of bone density, which can increase the risk of fractures. Prednisone and other corticosteroids can contribute to osteoporosis by interfering with the body's ability to absorb calcium, a crucial mineral for maintaining strong and healthy bones. Additionally, these medications can increase the rate at which bone tissue breaks down, further contributing to the development of osteoporosis.
The risk of prednisone-induced osteoporosis is higher in individuals who take the medication for prolonged periods, typically more than three months, and at higher doses. Age is also a factor, as older individuals are generally more susceptible to bone loss and fractures. It is important to note that inhaled steroids are generally less likely to cause bone loss than oral steroids, and steroids applied to the skin or used for a few days are not associated with bone loss.
To mitigate the risk of osteoporosis while taking prednisone, it is crucial to follow your doctor's instructions and monitor your bone health regularly. This may include undergoing bone density scans, such as dual-energy X-ray absorptiometry (DXA or DEXA), to detect any changes in bone density early on. Your doctor may also recommend preventative measures such as calcium and vitamin D supplements, a healthy diet, and physical activity to support bone health.
If osteoporosis develops during prednisone treatment, your doctor may advise you to take bone-strengthening medications or consider alternative treatments for your underlying condition. It is important to work closely with your healthcare provider to balance the benefits of prednisone against the potential risks to your bone health.
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Prednisone may cause cancer
I could not find specific information on whether prednisone causes muscle pain after stopping its use. However, I can provide some information on the side effects of stopping prednisone.
Prednisone is a common drug, often prescribed for long periods to treat many chronic conditions. It is a synthetic corticosteroid that reduces inflammation and lowers the body's immune response. While it can be used to treat certain types of cancer, it may also increase the risk of developing other types of cancer.
Prednisone may increase the risk of developing osteoporosis, a condition that weakens the bones and makes them more susceptible to fractures. In addition, some patients who took prednisone or similar medications developed a type of cancer called Kaposi's sarcoma. This is a rare form of cancer that typically affects the skin and mucous membranes.
While prednisone is not directly linked to causing cancer, it is important to consider the potential risks. A study of cancers that appeared within four years of drug use showed that prednisone was among 53 drugs associated with cancer at least once. However, the cases were primarily related to other factors such as cigarette smoking.
Furthermore, long-term use of prednisone can suppress the body's natural steroid production. Therefore, stopping prednisone suddenly can cause symptoms such as extreme tiredness, weakness, slowed movements, upset stomach, weight loss, changes in skin color, mouth sores, and salt cravings. It is crucial to consult a doctor before stopping prednisone to safely taper the dosage and minimize withdrawal symptoms.
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Prednisone may cause other side effects
While prednisone can be an effective medication for treating long-lasting diseases, it may cause several side effects, including muscle pain and weakness. It is important to consult a doctor before starting or stopping prednisone to ensure proper usage and monitoring of any adverse reactions.
One potential side effect of prednisone is muscle pain and weakness, which can occur as a result of corticosteroid-induced myopathy. This condition typically develops after taking higher doses of prednisone (more than 10 mg prednisone equivalents/day) for an extended period, usually four weeks or longer. Elderly individuals and women are at a higher risk for developing corticosteroid-induced myopathy, but it can affect anyone taking high doses of steroids for a prolonged period.
In addition to muscle pain and weakness, prednisone may cause other side effects, such as an increased risk of infection. This is because prednisone decreases the body's ability to fight off infections, making it crucial to avoid individuals who are sick and to practice good hand hygiene while taking this medication. Exposure to certain illnesses, such as chickenpox or measles, should be reported to a doctor immediately.
Prednisone may also cause bone thinning or osteoporosis, especially with long-term use. This side effect can increase the risk of fractures and other bone-related issues. Additionally, prednisone may slow growth and development in children, so it is important to closely monitor their progress and consult a doctor about the risks.
Furthermore, prednisone may increase the risk of developing certain types of cancer, such as Kaposi's sarcoma. It is important to be vigilant for any unusual symptoms or changes in the body and report them to a doctor promptly. Other possible side effects of prednisone include changes in weight, appetite, mood, and energy levels.
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Frequently asked questions
Prednisone is a medicine that comes in the form of a tablet, delayed-release tablet, solution (liquid), or concentrated solution to be taken by mouth.
Prednisone has several side effects, some of which are short-term, while others are associated with long-term use. Short-term side effects include an upset stomach, weight loss, changes in skin color, mouth sores, and a craving for salt. Long-term side effects include thinning of the bones (osteoporosis), an increased risk of cancer, and muscle pain and weakness.
Yes, prednisone is an oral steroid that can cause muscle pain and weakness. It is also associated with a condition called steroid-induced myopathy, which is a toxic non-inflammatory myopathy caused by the administration of exogenous corticosteroids.
If you experience muscle pain after taking prednisone, talk to your doctor or prescriber. They may recommend applying a hot or cold compress, trying massage therapy, or suggest over-the-counter (OTC) pain relievers such as ibuprofen.
Do not stop taking prednisone without talking to your doctor. If you suddenly stop taking the medication, your body may not have enough natural steroids to function normally, which can cause symptoms such as extreme tiredness, weakness, slowed movements, upset stomach, weight loss, changes in skin color, mouth sores, and craving for salt.











































