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Trelegy Ellipta is a brand-name medication prescribed for COPD and asthma in adults. It is an inhalation powder used to improve symptoms and prevent bronchospasm in adults with COPD and to prevent asthma symptoms in adults. While Trelegy Ellipta is an effective medication, it can cause side effects, including muscle pain and muscle spasms. In addition, it can also cause low potassium levels, which can lead to muscle cramps. It is important to consult a doctor if you experience any side effects to ensure proper management of symptoms.
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What You'll Learn
Trelegy Ellipta's side effects
Trelegy Ellipta is a prescription medication used to treat chronic obstructive pulmonary disease (COPD) and asthma in adults. It is a combination medication that contains fluticasone, umeclidinium, and vilanterol. While Trelegy Ellipta can be effective in managing these conditions, it is important to be aware of its potential side effects.
One of the most serious potential side effects of Trelegy Ellipta is reduced adrenal gland function, which can lead to symptoms such as nausea, excessive fatigue, changes in weight, and low blood pressure. Another rare but serious side effect is paradoxical bronchospasm, where the airways suddenly tighten after inhaling the medication, which can be life-threatening. Other serious side effects may include allergic reactions, fungal infections in the mouth or throat (thrush), weakened immune system, eye problems such as cataracts or glaucoma, and increased blood sugar levels.
Some of the more common side effects of Trelegy Ellipta include mild headaches, sore throat, and back pain. Upper respiratory tract infections, pneumonia, bronchitis, taste disturbances, constipation, and nausea are also commonly reported. Additionally, Trelegy Ellipta may cause muscle pain or weakness, but this is not a common side effect.
It is important to note that Trelegy Ellipta should not be used to relieve sudden breathing problems during asthma or bronchospasm attacks. It is also not recommended for use in children under 18 years of age. Always follow the instructions provided by your doctor or healthcare provider when using this medication, and be sure to report any side effects that occur.
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Low potassium levels
Trelegy Ellipta is a brand-name medication that can cause serious side effects, albeit rarely. One of these side effects is hypokalemia or low blood potassium. Normal levels of potassium for an adult are between 3.5 and 5.2 mEq/L (or mmol/L), and a level below 3 mEq/L may be considered severe hypokalemia.
Low blood potassium typically occurs due to excessive loss of potassium through vomiting, diarrhea, or laxative use. It can also be caused by eating disorders, excessive sweating, alcohol use disorder, diuretics, certain medications, adrenal disorders, and chronic kidney disease.
Other symptoms of low potassium levels include constipation, heart palpitations, extreme fatigue, tingling and numbness, muscle twitches, severe muscle weakness, low blood pressure, lightheadedness, abnormal heart rhythms, excessive urination, and excessive thirst.
If you suspect you have low potassium levels, it is important to consult a healthcare professional, who can advise on increasing your potassium intake and improving your overall health.
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Muscle pain and weakness
Trelegy Ellipta is a brand-name medication that is prescribed for COPD and asthma in adults. It is an inhalation powder used to improve symptoms and prevent bronchospasm in adults with COPD, including bronchitis and emphysema, and to prevent asthma symptoms in adults. It is not a rescue medicine for asthma or bronchospasm attacks.
Trelegy Ellipta can cause side effects, ranging from mild to serious. Mild side effects may include headaches, sore throat, and back pain. More serious side effects include reduced adrenal gland function, high blood sugar, and weakened immune system and increased chance of getting infections.
Trelegy Ellipta may also cause muscle pain and muscle weakness. Research suggests that muscle pain is linked to vilanterol, the LABA found in Trelegy Ellipta. Additional studies have also linked LABAs to nighttime leg cramps. If you have muscle pain while using this inhaler, talk to your healthcare provider so they can help you manage the symptoms.
If you experience muscle pain or weakness, muscle cramps, or an irregular heartbeat, these could be signs of low potassium. Let your care team know right away. Low potassium can affect your heart.
If you experience serious side effects, call your doctor right away. If the side effects seem life-threatening, immediately call your local emergency number.
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Trelegy Ellipta's interactions with other medicines
Trelegy Ellipta is a prescription inhalation powder used to treat asthma or COPD in adults. It contains the active ingredients fluticasone furoate, umeclidinium, and vilanterol.
Trelegy Ellipta can potentially interact with several other medications and substances. Here are some of the known interactions:
- Anticholinergics: Trelegy Ellipta should not be co-administered with other anticholinergic-containing drugs, as this may lead to increased anticholinergic adverse effects. Anticholinergics include medications like tiotropium, ipratropium, and aclidinium.
- Diuretics: Trelegy Ellipta can interact with certain diuretics used to treat high blood pressure and heart-related conditions. Taking Trelegy Ellipta with these diuretics may increase the risk of low blood potassium levels (hypokalemia), which can lead to heart rhythm changes, including long QT syndrome.
- Clarithromycin: This is an antibiotic used to treat bacterial infections. Combining clarithromycin with Trelegy Ellipta can increase the risk of side effects from Trelegy Ellipta because clarithromycin slows down the breakdown of Trelegy Ellipta in the body, leading to higher levels in the system.
- Sertraline, Prednisone, and Metoprolol: Trelegy Ellipta is known to interact with these specific medications, although the exact nature of the interaction is not mentioned in the sources.
- Alcohol: While Trelegy Ellipta is not known to interact directly with alcohol, both substances can cause similar side effects, including headaches and diarrhea. Therefore, drinking alcohol during Trelegy Ellipta treatment may increase the likelihood of experiencing these side effects.
- Other medications: Trelegy Ellipta may also interact with other medications, supplements, or herbs. It is important to inform your doctor and pharmacist about any other substances you are taking to prevent potential interactions.
It is crucial to consult your healthcare provider and carefully follow their instructions when taking Trelegy Ellipta. Do not change or stop taking any medications without first discussing it with your doctor.
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Trelegy Ellipta's long-term side effects
Trelegy Ellipta is an inhalation powder used to improve symptoms and prevent bronchospasm in adults with COPD, including bronchitis and emphysema, and to prevent asthma symptoms in adults. It is not a rescue medicine for asthma or bronchospasm attacks. It is a maintenance medicine for long-term use.
Trelegy Ellipta may cause serious side effects, but they are uncommon. The list below may not include all possible serious side effects of the drug. For more information, you can refer to Trelegy Ellipta’s prescribing information. If you develop serious side effects, call your doctor right away. If the side effects seem life-threatening, immediately call 911 or your local emergency number.
Serious side effects that have been reported include:
- Reduced adrenal gland function (in which your body doesn’t produce enough of certain hormones). Symptoms can include nausea, excessive fatigue, changes in weight, and low blood pressure.
- Hypokalemia (low blood potassium level). Symptoms can include muscle cramps, weakness, heart palpitations, and numbness or tingling.
- Increased blood sugar.
- Eye problems, such as cataracts or glaucoma.
Some of the more common side effects reported by people who took Trelegy Ellipta in clinical trials include:
- Headache
- Sore throat
- Back pain
Trelegy Ellipta can also cause an allergic reaction. Get emergency medical help if you have signs of an allergic reaction, including hives, difficulty breathing, and swelling of your face, lips, tongue, or throat.
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Frequently asked questions
Yes, Trelegy Ellipta can cause muscle pain and muscle spasms. Research suggests that muscle pain is linked to vilanterol, the LABA found in Trelegy Ellipta. Low potassium levels can also cause muscle cramps.
Trelegy Ellipta may cause serious side effects, but they are rare. Some common side effects include nausea, fatigue, weight changes, low blood pressure, and respiratory infections.
If you experience muscle cramps or any other side effects while taking Trelegy, you should consult your doctor or healthcare provider. They can help you manage the symptoms and determine if Trelegy is safe and effective for you.
Yes, potential long-term side effects of Trelegy Ellipta include serious infections such as pneumonia, decreased bone density, glaucoma, and cataracts. It is important to consult your doctor if you experience any side effects to determine the best course of action.
Yes, Trelegy Ellipta may cause allergic reactions in some individuals. If you experience symptoms such as a rash, itching, hoarseness, trouble breathing, or swelling of the hands, face, or mouth, seek immediate medical attention.
