Dominic Stone
Vitamin D is increasingly recognised to play an important role in normal muscle function and performance. Research suggests that active levels of vitamin D may improve muscle function and strength. Vitamin D deficiency is very common, and the signs are non-specific, so it is important to maintain a high index of suspicion of vitamin D deficiency in patients with muscle pain and weakness.
| Characteristics | Values |
|---|---|
| Muscle function | Active levels of vitamin D may improve muscle function |
| Muscle strength | Seven studies showed a positive effect of vitamin D treatment on muscle strength |
| Muscle performance | Vitamin D supplementation has been shown to improve tests of muscle performance |
| Muscle pain and weakness | Low vitamin D status is associated with an increased risk of falls and proximal weakness |
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What You'll Learn
Vitamin D deficiency and muscle weakness
Vitamin D deficiency is associated with an increased risk of falls and muscle weakness. It is important to maintain a high index of suspicion of vitamin D deficiency in patients with muscle pain and weakness, as the signs are non-specific and the therapy is cheap, safe and effective. Vitamin D is increasingly recognised to play an important role in normal muscle function.
Vitamin D status is positively associated with physical performance and inversely associated with the risk of falling. Vitamin D supplementation has been shown to improve tests of muscle performance, reduce falls, and possibly impact on muscle fibre composition and morphology in vitamin D deficient older adults.
Several studies have shown a positive effect of vitamin D treatment on muscle strength, postural sway and/or physical performance. However, some studies have found no evidence of effects on measured indices. More research is needed to fully characterise the underlying mechanisms of vitamin D action in human muscle tissue and to understand how these actions translate into changes in muscle cell morphology and improvements in physical performance.
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Vitamin D and physical performance
Vitamin D is increasingly recognised to play an important role in normal muscle function. Research suggests that active levels of vitamin D may improve muscle function and performance. Low vitamin D status is associated with an increased risk of falls and proximal weakness. Vitamin D deficiency is very common, and the signs are non-specific, so it is important to maintain a high index of suspicion of vitamin D deficiency in patients with muscle pain and weakness.
Therapy for vitamin D deficiency is cheap, safe and effective, but sometimes a larger dose may be needed. Vitamin D supplementation has been shown to improve tests of muscle performance, reduce falls, and possibly impact on muscle fibre composition and morphology in vitamin D deficient older adults.
A review of evidence from randomised controlled trials found that seven studies showed a positive effect of vitamin D treatment on muscle strength, postural sway and/or physical performance, whereas nine studies found no evidence of effects on measured indices. Further studies are needed to fully characterise the underlying mechanisms of vitamin D action in human muscle tissue, to understand how these actions translate into changes in muscle cell morphology and improvements in physical performance, and to define the 25-hydroxyvitamin D level at which to achieve these beneficial effects in muscle.
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Vitamin D and muscle pain
Vitamin D is increasingly recognised to play an important role in normal muscle function. Low vitamin D status is associated with an increased risk of falls and proximal weakness. Since vitamin D deficiency is very common, and the signs are non-specific, it is important to maintain a high index of suspicion of vitamin D deficiency in patients with muscle pain and weakness.
Vitamin D supplementation has been shown to improve tests of muscle performance, reduce falls, and possibly impact on muscle fibre composition and morphology in vitamin D deficient older adults. Seven studies showed a positive effect of vitamin D treatment on muscle strength, postural sway and/or physical performance, whereas nine studies found no evidence of effects on measured indices.
Vitamin D is key for the development and maintenance of healthy bones. It also has many positive effects on the immune system, endocrine glands, and cardiovascular system. Some observational studies have linked vitamin D deficiency with a higher risk of colorectal and breast cancer, while others have found a correlation between vitamin D levels and the risk of autoimmune diseases such as type 1 diabetes and multiple sclerosis.
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Vitamin D and muscle strength
Vitamin D is increasingly recognised to play an important role in normal muscle function. Research suggests that active levels of vitamin D may improve muscle function and performance. Vitamin D is key for the development and maintenance of healthy bones, and it has many positive effects on the immune system, endocrine glands, and cardiovascular system.
Observational studies have linked vitamin D deficiency with an increased risk of falls and proximal weakness. Low vitamin D status is also associated with a higher risk of colorectal and breast cancer, as well as autoimmune diseases such as type 1 diabetes and multiple sclerosis.
Seven studies have shown a positive effect of vitamin D treatment on muscle strength, postural sway and/or physical performance. Vitamin D supplementation has been shown to improve tests of muscle performance, reduce falls, and possibly impact muscle fibre composition and morphology in vitamin D deficient older adults.
However, nine studies found no evidence of effects on measured indices. Further studies are needed to fully characterise the underlying mechanisms of vitamin D action in human muscle tissue, to understand how these actions translate into changes in muscle cell morphology and improvements in physical performance, and to define the 25-hydroxyvitamin D level at which to achieve these beneficial effects in muscle.
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Vitamin D and muscle function
Vitamin D is increasingly recognised to play an important role in normal muscle function. Research suggests that active levels of vitamin D may improve muscle function and performance. Low vitamin D status is associated with an increased risk of falls and proximal weakness. Vitamin D deficiency is very common, and the signs are non-specific, so it is important to maintain a high index of suspicion of vitamin D deficiency in patients with muscle pain and weakness. Vitamin D supplementation has been shown to improve tests of muscle performance, reduce falls, and possibly impact on muscle fibre composition and morphology in vitamin D deficient older adults.
Seven studies have shown a positive effect of vitamin D treatment on muscle strength, postural sway and/or physical performance. However, nine studies found no evidence of effects on measured indices. Further studies are needed to fully characterise the underlying mechanisms of vitamin D action in human muscle tissue, to understand how these actions translate into changes in muscle cell morphology and improvements in physical performance, and to define the 25-hydroxyvitamin D level at which to achieve these beneficial effects in muscle.
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Frequently asked questions
Yes, vitamin D is increasingly recognised to play an important role in normal muscle function.
Vitamin D is key for the development and maintenance of healthy bones, and has positive effects on the immune system, endocrine glands, and cardiovascular system.
The signs of vitamin D deficiency are non-specific, but can include muscle pain and weakness, and an increased risk of falls.
Vitamin D deficiency can be treated with vitamin D supplements, which are cheap, safe and effective.
The best way to get vitamin D is through exposure to sunlight, but it can also be found in certain foods such as fatty fish, egg yolks, and fortified dairy products.
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