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Vyvanse is a prescription medication used to treat attention deficit hyperactivity disorder (ADHD) in adults and children. Lisdexamfetamine, the active ingredient in Vyvanse, is a central nervous system stimulant that can cause muscle pain and stiffness. While muscle tension is not listed as a common side effect of Vyvanse, some people who have taken the medication have reported experiencing it. Other side effects of Vyvanse include cardiovascular problems, serotonin syndrome, and allergic reactions.
| Characteristics | Values |
|---|---|
| Active ingredient | Lisdexamfetamine |
| Side effects | Muscle tension, pain, sleep problems, headaches, cardiovascular problems, serotonin syndrome, Raynaud phenomenon, allergic reaction, abuse, misuse, addiction |
| Overdose symptoms | Agitation, blurred vision, change in consciousness, chest pain or discomfort, confusion, dark urine, diarrhea, dizziness, faintness, or lightheadedness, irregular heartbeat, fever, headache, inability to speak, loss of consciousness, muscle cramps, spasms, nausea, nervousness, overactive reflexes, pain or discomfort in the arms, jaw, back, or neck, pale or clammy skin, palpitations, pounding in the ears, hallucinations, seizures, shivering, slurred speech, sweating, excitement |
| FDA warning | Risk of misuse and dependence |
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What You'll Learn
Lisdexamfetamine, the active ingredient in Vyvanse
Lisdexamfetamine dimesylate, the active ingredient in Vyvanse, is a prodrug stimulant used in the treatment of attention deficit hyperactivity disorder (ADHD) and binge eating disorder. It is available in 10 mg, 20 mg, 30 mg, 40 mg, 50 mg, 60 mg, and 70 mg oral capsules and chewable tablets. The exact mechanism by which lisdexamfetamine works in the body to treat these conditions is not known. However, it is believed to involve the conversion of the prodrug to the active drug d-amphetamine through enzymatic hydrolysis. This process results in the formation of the naturally occurring amino acid l-lysine as a by-product.
Lisdexamfetamine has been reported to cause muscle pain, cramping, and stiffness, with some patients experiencing severe muscle pain and stiffness. These side effects are thought to be related to the stimulant nature of the medication, as other stimulant medications have also been associated with muscle tension and pain. Additionally, lisdexamfetamine may cause allergic reactions, and there is a risk of misuse, substance abuse, overdose, and death if not taken as prescribed. Other less common but serious side effects include increased blood pressure and heart rate.
The advantages of lisdexamfetamine as a treatment for ADHD include its long-acting nature, providing efficacy throughout the day with once-daily dosing. It also exhibits low rates of inter-patient and intrapatient pharmacokinetic variability, a reduced risk of pH-mediated food or drug interactions, and a lower potential for abuse or diversion compared to other formulations. Lisdexamfetamine has been approved by the FDA for the treatment of ADHD in adults and children aged 6 to 12 years.
It is important to note that the side effects of lisdexamfetamine may vary depending on the individual and the dosage prescribed. Patients experiencing any bothersome side effects or severe muscle pain should consult their healthcare provider. Additionally, lisdexamfetamine should be stored at room temperature between 68°F to 77°F (20°C to 25°C) and disposed of properly through medicine take-back programs or by mixing with nontoxic substances before throwing away.
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Potential allergic reactions
Vyvanse (lisdexamfetamine) is a medication used to treat attention deficit hyperactivity disorder (ADHD) in adults and children. While it can be effective, it may also cause certain side effects, including some that are serious. If you experience any of the following symptoms of a potential allergic reaction, call your doctor right away for mild symptoms or 911 for severe symptoms.
Mild allergic reaction symptoms include:
Mild rash
Your doctor may recommend treatments to help manage your symptoms and advise whether you should continue taking the medication.
Severe allergic reaction symptoms include:
- Swelling of the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
- Trouble breathing
These symptoms require immediate medical attention as they can become life-threatening. If you experience a severe allergic reaction to Vyvanse, your doctor may recommend alternative medications.
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Cardiovascular problems
Vyvanse (lisdexamfetamine) is a drug used to treat attention deficit hyperactivity disorder (ADHD) in adults and children. It has a high potential for abuse and misuse, which can lead to the development of a substance use disorder, including addiction. The misuse of CNS stimulants, including lisdexamfetamine dimesylate, can result in overdose and even death.
Vyvanse may cause serious cardiovascular problems, including:
- Increased blood pressure
- Heart attack
- Stroke
These cardiovascular issues can be life-threatening, so it is important to be aware of the signs and symptoms and seek medical attention if necessary.
Vyvanse may also cause other side effects, such as:
- Headaches
- Sleep problems
- Allergic reactions
- Overdose symptoms, such as agitation, blurred vision, change in consciousness, confusion, and more
If you experience any side effects from taking Vyvanse, it is important to consult your doctor or pharmacist. They can provide guidance and help determine if any adjustments to medication or dosage are needed.
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Raynaud's phenomenon
Vyvanse (lisdexamfetamine) is a prescription drug used to treat attention deficit hyperactivity disorder (ADHD) and binge eating disorder (BED). It is a stimulant medication that alters the balance of chemicals in the brain and can cause a range of side effects, from mild to severe.
RP can be primary (idiopathic) or secondary to an underlying cause. Secondary RP is associated with autoimmune diseases such as systemic sclerosis, lupus, and vasculitis, as well as other systemic diseases. Drug-induced RP has been linked to various medications, including stimulants used to treat ADHD, beta-blockers, chemotherapy drugs, and over-the-counter cold remedies. The condition is characterized by changes in skin colour, ranging from white to blue to red, and can cause numbness, pain, blistering, and, in severe cases, tissue necrosis.
Vyvanse has been specifically mentioned as a potential trigger for Raynaud's phenomenon. It is advised that individuals discuss their health history and any concerns about Raynaud's phenomenon with their doctor before taking Vyvanse. While Vyvanse can be an effective treatment option for ADHD and eating disorders, it is important to be aware of potential side effects and drug interactions, including the possibility of developing Raynaud's phenomenon.
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Abuse, misuse, and addiction
Vyvanse, the brand name for lisdexamfetamine dimesylate, is a prescription central nervous system stimulant for the treatment of attention deficit hyperactivity disorder (ADHD) and moderate to severe binge eating disorder in adults. Similar to many prescription stimulants, Vyvanse can be misused and can lead to addiction, dependence, and other adverse effects.
Given its prescription status, many people assume Vyvanse is safe even if they misuse it. However, as a Schedule II drug, Vyvanse has a high potential for abuse and dependence. The warnings on its drug label indicate that its use can lead to tolerance, dependence, addiction, overdose, and even death.
Ongoing misuse of central nervous system stimulants like Vyvanse can hasten the development of tolerance, physiological dependence, and addiction. With tolerance, the drug's effects become less pronounced over time, leading to larger doses to achieve the desired effect. Dependence means a person's system adapts to the presence of the drug, and they will only feel "normal" when the drug is present. When a person stops taking the drug, they can experience withdrawal symptoms, including significant fatigue and depression.
Signs and symptoms of central nervous system stimulant misuse can include hyperactivity, restlessness, increased heart rate, blood pressure, and respiratory rate, flushed skin, increased sweating, dilated pupils, abdominal pain, decreased appetite, loss of coordination, anxiety, aggression, hostility, suicidal and homicidal ideation, and psychosis. It is important to note that Vyvanse carries serious cardiovascular risks, including increased heart rate and blood pressure, as well as more serious reactions such as stroke, heart attack, and sudden death in people with pre-existing heart issues.
Vyvanse withdrawal is rarely fatal but can be intense and challenging to navigate alone. Addiction treatment can help manage and address withdrawal symptoms, providing a safer path to recovery.
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Frequently asked questions
Vyvanse is a prescription medication used to treat attention deficit hyperactivity disorder (ADHD) in adults and children.
Vyvanse's active ingredient, lisdexamfetamine, is known to cause muscle pain and stiffness in some patients. However, this side effect has also been reported by patients taking Vyvanse, with some experiencing neck and shoulder muscle tension and pain.
Vyvanse may cause serious side effects, including cardiovascular problems (such as increased blood pressure, heart attack, and stroke), blood circulation issues in the fingers and toes (Raynaud's disease), serotonin syndrome, allergic reactions, and sleep problems.
If you experience any side effects while taking Vyvanse, consult your doctor or pharmacist immediately. Some side effects may be temporary and go away within a few days or weeks, but it's important to seek medical advice to ensure your safety and well-being.
