
Muscle spasms are painful, involuntary contractions of muscles that can affect anyone at any time. While usually not serious, they can be indicative of a more serious underlying medical condition. They can be caused by muscle strain, nerve damage, or certain medications. If you are experiencing muscle spasms caused by pain medication, there are several ways to stop them. Firstly, it is important to consult your doctor, as they may recommend reducing your dosage or switching to an alternative medication. Non-medication treatments such as hot or cold compresses, massage therapy, and over-the-counter pain relievers like ibuprofen can also help alleviate muscle spasm symptoms. Additionally, muscle relaxants and antispasmodics may be prescribed for severe or frequent muscle spasms, but these can have side effects such as drowsiness and dizziness.
| Characteristics | Values |
|---|---|
| Muscle spasms | Painful contractions and tightening of your muscles |
| Causes | Too much muscle strain, lower back pain, neck pain, fibromyalgia, cerebral palsy, multiple sclerosis (MS), amyotrophic lateral sclerosis (ALS), spinal cord injury, brain or head injury |
| Treatment | Over-the-counter (OTC) pain relievers like ibuprofen or acetaminophen, massage therapy, cool or hot compress, stretching, muscle relaxants (e.g. carisoprodol, diazepam, baclofen), antispasmodics, nonsteroidal anti-inflammatory drugs (NSAIDs), gabapentin |
| Prevention | Avoiding medications that cause muscle spasms as a side effect, reviewing health history and medications, sleeping with toes pointed upward, stretching before sleep, keeping sheets and blankets loose |
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What You'll Learn

Reduce your dose or stop taking the medication
If you are experiencing muscle spasms as a side effect of your pain medication, it is important to consult your doctor or healthcare provider. They may advise you to reduce your dose or stop taking the medication altogether, but it is crucial not to make any changes without first seeking professional advice.
In some cases, reducing the dosage of certain medications can help alleviate muscle spasms and pains. For example, statins are a well-known cause of muscle pain, and lowering the dosage can reduce this side effect. Similarly, isotretinoin, a medication for severe acne, can cause muscle pain and spasms, which may lessen with a lower dose. It is important to note that you should not adjust your dosage without consulting your doctor or pharmacist first.
If your muscle spasms are severe or persist after dose adjustment, your healthcare provider may recommend discontinuing the medication. This is especially true for medications that are not considered absolutely necessary or have alternative treatment options available. For example, pregabalin (Lyrica) is known to cause muscle spasms and joint pain, and patients experiencing these side effects may be advised to switch to an alternative nerve medication, such as gabapentin, that does not have the same issues. Similarly, bisphosphonates, which are used to treat osteoporosis, can cause muscle and joint pain, and patients are advised to stop taking them if the pain becomes severe and consult their doctor for alternative treatments.
It is important to remember that stopping certain medications abruptly can have risks and side effects. For instance, muscle relaxants like carisoprodol and diazepam can be habit-forming, and discontinuing them suddenly can lead to withdrawal symptoms such as seizures or hallucinations. Therefore, it is imperative to seek medical advice before making any changes to your medication regimen.
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Try over-the-counter painkillers like ibuprofen or acetaminophen
If you are experiencing muscle spasms caused by pain medication, there are a few over-the-counter (OTC) painkillers that you can try to help manage the pain. Ibuprofen and acetaminophen are two effective options. Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that can help reduce inflammation and pain associated with muscle spasms. It works by blocking the production of certain substances in your body that cause inflammation and pain. NSAIDs are easily available over the counter and typically come in the form of oral tablets, capsules, or suspensions.
Acetaminophen is another OTC medication that can help relieve pain from muscle spasms. It is often recommended as a first-line therapy for muscle spasms caused by conditions such as acute lower back pain or tension headaches. Acetaminophen has fewer side effects compared to some prescription muscle relaxants and antispasmodics. It is important to note that acetaminophen does not have anti-inflammatory properties like NSAIDs, but it can still effectively manage pain.
In addition to ibuprofen and acetaminophen, other NSAIDs are available over the counter and can provide similar relief from pain and inflammation. These medications are typically sold under different brand names, so be sure to read the labels carefully to identify the active ingredient.
While OTC painkillers can help manage the pain associated with muscle spasms, they may not directly address the underlying cause. If you are experiencing severe or frequent muscle spasms, it is important to consult your healthcare provider. They may recommend muscle relaxers or other prescription medications to help ease your symptoms. Additionally, reviewing your health history and current medications with your provider can help identify any medications that may be contributing to your muscle spasms.
To further manage muscle spasms, there are some non-medication treatments you can try alongside OTC painkillers. These include stretching the affected area, massaging the muscle, applying heat or ice, and ensuring proper sleep positioning to prevent leg cramps.
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Use muscle relaxants like carisoprodol or diazepam
Muscle relaxants such as carisoprodol and diazepam can be used to treat muscle spasms. Carisoprodol is a controlled substance and a prescription drug that works by acting on the brain and nervous system to allow muscles to relax. It is typically taken orally three times a day and at bedtime, with or without food. It is important to note that carisoprodol can be habit-forming, and one should not take a larger dose or use it more frequently or for longer than prescribed. In addition, it may cause an allergic reaction, with symptoms such as hives, difficulty breathing, and swelling of the face, lips, tongue, or throat.
Diazepam, also known by its brand name Valium, is another muscle relaxant that has been used to treat muscle spasms. It is rated positively by 85% of reviewers, with an average rating of 8.6 out of 10. It is typically taken twice a day, around 10-12 hours apart. Diazepam is a sedative and can cause side effects such as drowsiness, fatigue, and muscle weakness. Similar to carisoprodol, diazepam can also be habit-forming and should not be stopped abruptly as it may cause withdrawal symptoms. It is important to consult a doctor or pharmacist for advice on the benefits and risks of these medications for treating muscle spasms.
It is worth noting that muscle relaxants are typically used in conjunction with rest and physical therapy to alleviate muscle spasms. They are thought to work by producing a sedative effect or by preventing nerves from transmitting pain signals to the brain. While they can be effective, muscle relaxants are generally recommended for short-term use, typically for up to 2 to 3 weeks, as the safety of long-term use is not yet established.
Before taking any medication, it is important to consult a healthcare professional and carefully read the medication leaflet.
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Try non-medication treatments like stretching, massage, hot or cold compresses
If you are experiencing muscle spasms caused by pain medication, there are several non-medication treatments you can try to alleviate the discomfort.
Stretching
Stretching is an effective way to reduce muscle spasms. It is recommended to stretch the affected area when a spasm occurs and to also incorporate regular flexibility exercises into your routine to reduce the overall risk of spasms. Stretching helps to relieve muscular tension and fatigue caused by the overuse or overstretching of a muscle.
Massage
Massage therapy is another treatment option that can help to reduce muscle spasms. Massage relieves the build-up of tension in muscles by increasing oxygenation and blood flow, which supplies muscles with oxygen and nutrients, maintaining their health and strength. Massage also helps to remove waste products from muscles, preventing fatigue and weakness, which can contribute to spasms. Common types of massage used to reduce muscle spasms include deep tissue massage, remedial massage, and Swedish massage.
Hot or Cold Compresses
Applying a hot or cold compress to the affected area can help to alleviate muscle spasms. Using a damp towel with warm water can help to reduce muscle spasms by increasing blood flow to the area, reducing joint stiffness, and easing pain. It is important to note that heat should not be applied within the first 48 hours after an injury. Cold compresses, on the other hand, can be used to numb the affected area, reducing pain, swelling, and inflammation.
Remember to always consult with a healthcare professional before starting any new treatment, especially if you are experiencing severe or frequent muscle spasms.
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Consult your doctor about alternative medications
If you are experiencing muscle spasms caused by pain medication, it is important to consult your doctor about alternative medications. They may recommend a different medication with fewer side effects or suggest adjusting your dosage. For instance, if you are experiencing muscle pain or weakness while taking a fibrate, it is important to inform your doctor, especially if you are also experiencing feverish or sick symptoms. They may advise you to lower your dosage, as in many cases, reducing the dose can help alleviate muscle pain.
Additionally, your doctor may suggest switching to a different medication that is less likely to cause muscle spasms as a side effect. For instance, if you are taking pregabalin and experiencing muscle spasms, your doctor may recommend switching to an alternative nerve medication, such as gabapentin, which is not associated with the same musculoskeletal issues. It is important to remember that you should not stop taking your current medication or adjust your dosage without first consulting your doctor.
In some cases, your doctor may prescribe muscle relaxants to help manage your muscle spasms. These medications work by acting on your central nervous system to produce a sedative effect or prevent your nerves from sending pain signals to your brain. Examples of muscle relaxants include carisoprodol and diazepam. However, it is important to be cautious when taking these medications, as they can be habit-forming and cause side effects such as drowsiness, fatigue, and muscle weakness. Therefore, it is crucial to follow your doctor's instructions and take the medication exactly as prescribed.
Furthermore, your doctor may recommend non-medication treatment options to help manage your muscle spasms. These can include applying a cool or hot compress to the affected area, massage therapy, or regular exercise to improve joint mobility and strengthen your muscles. They may also suggest over-the-counter (OTC) pain relievers, such as ibuprofen or acetaminophen, to help manage any pain associated with the muscle spasms. Remember that your doctor will work with you to find the most suitable combination of therapies to achieve a manageable quality of life with your condition.
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Frequently asked questions
Muscle spasms are painful, involuntary contractions of a muscle or group of muscles. They are unpredictable and can happen to anyone at any time, but they are usually not serious.
If you are experiencing muscle spasms as a side effect of your medication, talk to your prescriber. They may ask you to reduce your dose or recommend a different medication. You can also try non-medication treatments such as applying a hot or cold compress, getting a massage, or trying over-the-counter (OTC) pain relievers like ibuprofen or acetaminophen.
Muscle relaxers are prescription medications that help regulate muscle contraction to reduce pain and discomfort caused by muscle spasms. They are typically used for short periods of time, as long-term use may cause side effects such as drowsiness and fatigue.
Common muscle relaxers include carisoprodol, cyclobenzaprine, and diazepam. Baclofen is often used to treat spasticity, especially in adults with spinal cord injuries.











































