
The corpora cavernosa are two expandable erectile tissues along the length of the penis, which fill with blood during penile erection. They are made of a sponge-like tissue containing trabeculae, irregular blood-filled spaces lined by endothelium and separated by septum of the penis. While the corpora cavernosa are not muscles, they do contain smooth muscle cells and are surrounded by muscles such as the ischiocavernosus and bulbocavernosus muscles, which aid in ejaculation.
| Characteristics | Values |
|---|---|
| Definition | Corpora cavernosa are the spongy tissue in the penis or vagina |
| Location | Corpora cavernosa are located along the length of the penis shaft, from the pubic bones to the head of the penis |
| Composition | Corpora cavernosa are composed of expandable erectile tissues, blood-filled spaces, smooth muscle cells, collagen, elastic fibres, loose areolar tissue, and fibroblasts |
| Function | Corpora cavernosa fill with blood during penile erection, aiding in sexual function |
| Disorders | Peyronie's disease, fibrosis, penile trauma, and priapism can affect the corpora cavernosa and cause sexual dysfunction |
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What You'll Learn

Corpora cavernosa is made of smooth muscle cells
The corpora cavernosa are two expandable erectile tissues along the length of the penis or, in females, the clitoris. They fill with blood during penile erection. The two corpora cavernosa lie along the penile shaft, from the pubic bones to the head of the penis, where they join.
The corpora cavernosa are made of smooth muscle cells. They are surrounded by elastic fibres, collagen, and loose areolar tissue. The tunica albuginea, a thick fibrous sheath, surrounds the whole cavernosal erectile tissue. The tunica albuginea of the corpus spongiosum is thinner than that of the corpora cavernosa. The tunica albuginea becomes thicker ventrally, where it forms a groove to accommodate the corpus spongiosum.
The corpora cavernosa contain open spaces called sinusoids, which are surrounded by smooth muscle cells. The sinusoids are lined with endothelium and are larger in the centre and smaller in the periphery. The sinusoids are cavernous spaces that fill with blood during an erection. The tunica albuginea contains flattened columns or sinusoidal trabeculae composed of fibrous tissue and smooth muscle.
The main cellular components of corporal tissue consist of cavernosal smooth muscle and endothelial cells. In the flaccid state, the trabecular smooth muscle and the central cavernous smooth muscle contract, allowing venous outflow and a return to the basal level of intracorporeal pressure.
Cultured human corporal smooth muscle cells can be used in conjunction with biodegradable polymers to create cavernosal smooth muscle tissue in vivo.
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Corpora cavernosa is a key structure for penile erection
Corpora cavernosa is a Latin term that refers to the "cavities/hollows" of the penis. The penis consists of three cylindrical erectile bodies: the ventral corpus spongiosum and a pair of corpus cavernosum. The corpora cavernosa are two expandable erectile tissues that run along the length of the penis, filling with blood during penile erection. The two corpora cavernosa lie along the penile shaft, from the pubic bones to the head of the penis, where they join.
The corpora cavernosa are made of a sponge-like tissue containing trabeculae, irregular blood-filled spaces lined by endothelium and separated by a septum of the penis. The male anatomy has no vestibular bulbs, but instead a corpus spongiosum, a smaller region of erectile tissue along the bottom of the penis, which contains the urethra and forms the glans penis.
During erection, the pressure in the corpus spongiosum and the glans is only one-third of that in the corpora due to the thin tunical covering allowing only minimal venous occlusion. In the rigid erectile phase, the ischiocavernosus and bulbocavernosus muscles forcibly compress the veins, allowing further engorgement of the spongiosum and glans.
Penile erection is mediated by the corpora cavernosa, a trabecular-like vascular bed that enlarges upon vasodilation. Perivascular fibroblasts in the corpora cavernosa support vasodilation by reducing norepinephrine availability. The effect on penile blood flow depends on the number of fibroblasts, which is regulated by erectile activity. Erection dynamically alters the positional arrangement of fibroblasts, temporarily down-regulating Notch signaling. Inhibition of Notch increases fibroblast numbers and consequently raises penile blood flow.
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Corpora cavernosa is susceptible to penile trauma
Corpora cavernosa are two expandable erectile tissues along the length of the penis, which fill with blood during penile erection. The two corpora cavernosa lie along the penile shaft, from the pubic bones to the head of the penis, where they join. The penis contains three cylindrical tissues: the ventral corpus spongiosum and dorsally a pair of corpora cavernosa. The corpora cavernosa are susceptible to penile trauma, which can cause a penile fracture, a rare but serious condition that requires emergency diagnosis and intervention.
Penile trauma can occur when the erect penis hits against the perineum or pubic symphysis during sexual intercourse, which is the most common cause in Western populations. The force of the impact can cause the penis to bend backward, resulting in a fracture. During penile trauma, the tunica albuginea, a thick fibrous sheath that surrounds the whole cavernosal erectile tissue, is breached, leading to a rupture of the corpora cavernosa. This can result in penile swelling, hematoma, and urethral bleeding. More than half of the patients with penile trauma report hearing a snap or cracking sound during the injury.
Penile trauma with associated rupture of the corpora cavernosa is a urological emergency, and surgical treatment is usually the standard care. Immediate surgical repair can help avoid short-term and long-term complications such as urethral stricture and ensure better patient outcomes and satisfaction. However, there are also conservative treatments for penile trauma, such as pressure dressing, cold compress, Foley catheterization, anti-inflammatory drugs, antibiotics, antiandrogens, or sedatives.
It is important to note that penile trauma can lead to permanent damage to the corpora cavernosa, causing future sexual problems and erectile dysfunction. Therefore, prompt diagnosis and treatment are crucial to prevent further complications and ensure optimal recovery.
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Corpora cavernosa is affected by Peyronie's disease
The corpora cavernosa are two expandable erectile tissues along the length of the penis, which fill with blood during penile erection. The two corpora cavernosa lie along the penile shaft, from the pubic bones to the head of the penis, where they join. The penis contains three cylindrical tissues: the ventral corpus spongiosum and dorsally a pair of corpus cavernosum. The corpora cavernosa are made of a sponge-like tissue containing trabeculae, irregular blood-filled spaces lined by endothelium and separated by septum of the penis.
Peyronie's disease is believed to be induced by penile trauma, either acute or chronic. It is quite common, affecting around one in 11 men, but it lacks public awareness. The disease typically presents with a sudden onset, followed by progression and then stabilisation. In some cases, the deformity may resolve spontaneously if it has not stabilised for more than six months. The management of the disease depends on its extent, the severity of the penile defect, and the impact on erectile function.
The formation of penile plaques and the impact on corpora cavernosa in Peyronie's disease have been studied using electron microscopy. The disease process does not usually affect the sinusoidal tissue within the corpora cavernosa but can impact the veins exiting, causing veno-occlusive disease of the penis. This can lead to difficulty in maintaining erections and pain during sexual intercourse.
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Corpora cavernosa is a sponge-like tissue
The corpora cavernosa are made of a sponge-like tissue containing trabeculae, irregular blood-filled spaces lined by endothelium and separated by septum of the penis. The tunica albuginea becomes thicker ventrally, where it forms a groove to accommodate the corpus spongiosum, which is a smaller region of erectile tissue along the bottom of the penis that contains the urethra and forms the glans penis. The corpus spongiosum possesses a much thinner and more elastic tunica albuginea to allow for the distention of the corpus spongiosum for the passage of the ejaculate through the urethra.
The corpora cavernosa is composed of cavernosal smooth muscle and endothelial cells. The main cellular components of corporal tissue consist of cavernosal smooth muscle and endothelial cells. The erectile tissue within the corpora contains arteries, nerves, muscle fibres, and venous sinuses lined with flat endothelial cells. The tunica albuginea of the corpora cavernosa is approximately 2 mm thick, while that of the corpus spongiosum is less than 0.5 mm thick.
The corpora cavernosa is important for sexual function and can be affected by various conditions, such as fibrosis, which is the thickening of connective tissue and blood vessels that cause scarring and loss of smooth muscle cells. Other conditions that can affect the corpora cavernosa include persistent genital arousal disorder in women, which can lead to painful, prolonged engorgement of the clitoris. It is important to seek medical attention for certain conditions to prevent permanent damage to the corpora cavernosa and future sexual problems.
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Frequently asked questions
Corpora cavernosa is the spongy tissue in the penis or vagina.
Corpora cavernosa are two expandable erectile tissues along the length of the penis, which fill with blood during penile erection.
Corpora cavernosa is made of a sponge-like tissue containing trabeculae, irregular blood-filled spaces lined by endothelium and separated by septum of the penis.
The corpus spongiosum is a smaller region of erectile tissue along the bottom of the penis, which contains the urethra and forms the glans penis. The corpora cavernosa are two erectile tissues along the length of the penis, from the pubic bones to the head of the penis.
Some common disorders of the corpora cavernosa include Peyronie's disease, penile trauma or fracture, and priapism.











































