
The pericardium is a double-walled sac that surrounds the heart and the roots of the major heart vessels. It is made up of two layers: the outer fibrous pericardium, which is composed of thick fibrous connective tissue, and the inner serous pericardium, a thin serous membrane. The fibrous pericardium is semi-rigid, while the serous pericardium is pliable, allowing the pericardium to protect the heart and restrict its movement. The serous pericardium is also divided into two parts: the parietal serous pericardium, which lines the interior of the fibrous pericardium, and the visceral serous pericardium, or epicardium, which covers the myocardium of the heart. So, is the pericardium a muscle?
| Characteristics | Values |
|---|---|
| Definition | A double-walled sac that contains the heart and the roots of the great vessels |
| Layers | Two: an outer layer made of strong inelastic connective tissue (fibrous pericardium) and an inner layer made of serous membrane (serous pericardium) |
| Function | Separates the heart from interference of other structures, protects it against infection and blunt trauma, lubricates the heart's movements, and prevents excessive dilation in cases of acute volume overload |
| Inflammation | Pericarditis, which typically causes chest pain that spreads to the back and is made worse by lying flat |
| Treatment | Pericardiectomy, pericardiocentesis, or pericardial window/pericardiostomy in case of recurrent pericardial effusion |
| Etymology | The English name originates from the Ancient Greek prefix peri- (περί) 'around' and the suffix -cardion (κάρδιον) 'heart' |
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What You'll Learn
- The pericardium is a sac that surrounds the heart and great vessels
- It has two layers: an outer fibrous pericardium and an inner serous pericardium
- The serous pericardium has two parts: parietal and visceral serous pericardium
- The pericardium prevents excessive dilation of the heart and protects it from infection
- Pericardial disease can occur as an isolated process or as a symptom of another disease

The pericardium is a sac that surrounds the heart and great vessels
The pericardium is a sac that surrounds the heart and the roots of the great vessels. It is a double-walled sac with two layers: the outer layer, or fibrous pericardium, and the inner layer, or serous pericardium. The fibrous pericardium is made of strong inelastic connective tissue, while the serous pericardium is a serous membrane made of a thin layer of mesothelium and loose connective tissue. The serous pericardium is also referred to as the epicardium.
The pericardium has several important functions, including setting the heart in the mediastinum and limiting its motion, protecting it from infection, lubricating it, and preventing excessive dilation in cases of acute volume overload. The pericardium also equalizes hydrostatic, inertial, and gravitational forces, helping to maintain the geometry of the left ventricle.
The fibrous pericardium is semi-rigid and provides protection for the heart against blunt forces and sudden pressure changes from the outside. It is fused with the central fibrous area of the diaphragm and attached to the posterior surface of the sternum by the sternopericardial ligaments. The serous pericardium, on the other hand, is quite pliable and functions to lubricate the heart to prevent friction during heart activity.
Between the two layers of the pericardium is the pericardial cavity, a potential space filled with a small amount of serous pericardial fluid. This fluid is secreted by pericardial cells and helps to reduce friction between the layers during heart contractions. The pericardial cavity is enclosed by the fibrous pericardium on the outside and the serous pericardium on the inside, with the serous pericardium also covering the heart as the epicardium.
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It has two layers: an outer fibrous pericardium and an inner serous pericardium
The pericardium is a double-walled sac that contains the heart and the roots of the great vessels. It is also referred to as the pericardial sac and is a thin layer of tissue that covers the outside of the heart. The pericardium has two layers: an outer fibrous pericardium and an inner serous pericardium. The fibrous pericardium is the outside layer of the pericardium, made up of thick, dense, and irregular connective tissue. It is semi-rigid and non-pliable, providing protection to the heart against outside forces and pressure changes. The fibrous pericardium is fused with the central fibrous area of the diaphragm and attached to the posterior surface of the sternum by the sternopericardial ligaments.
The serous pericardium, on the other hand, is quite pliable and is physically much closer to the heart. It is a serous membrane that consists of two parts: the parietal serous pericardium and the visceral serous pericardium. The parietal layer lines the interior side of the pericardial sac and is inseparable from the fibrous pericardium. The visceral layer, also known as the epicardium, covers the myocardium of the heart and is considered its serosa. It is made up of a mesothelium overlying some elastin-rich loose connective tissue.
Between the two layers of the pericardium is the pericardial cavity, a potential space filled with a small amount of serous pericardial fluid. This fluid lubricates the layers and prevents friction during heart contractions. The basic function of the pericardium is to provide mechanical protection to the heart, and the fluid between the layers helps cushion the heart from external jerks or shocks. The pericardium also separates the heart from interference by other structures, protects it against infection, and prevents excessive dilation.
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The serous pericardium has two parts: parietal and visceral serous pericardium
The pericardium is a membrane that encloses the heart and the roots of the major heart vessels. It is made up of two layers: the outer fibrous pericardium and the inner serous pericardium. The serous pericardium, in turn, is divided into two parts: the parietal serous pericardium and the visceral serous pericardium.
The parietal serous pericardium is the outer layer of the serous pericardium. It lines the interior side of the superficial portion of the pericardial sac and is fused to and inseparable from the fibrous pericardium. The fibrous pericardium is semi-rigid and made of dense and loose connective tissue, while the parietal serous pericardium is quite pliable.
The visceral serous pericardium, also known as the epicardium, is the inner layer of the serous pericardium. It covers the myocardium of the heart and can be considered its serosa. It is largely made of a mesothelium overlying some elastin-rich loose connective tissue. The visceral serous pericardium is the layer that is in direct contact with the heart and is responsible for lubricating the heart to prevent friction during heart activity.
Between the parietal and visceral layers of the serous pericardium is the pericardial cavity, a potential space filled with 15-50 milliliters of serous pericardial fluid. This fluid is secreted by pericardial cells and helps to reduce friction between the layers during heart contractions. The layers are separated, but at two places the parietal layer reflects toward the visceral and fuses with it, forming dead ends (cul-de-sacs) to keep the pericardial cavity closed.
The pericardium serves several important functions for the heart. It helps to set the heart in the mediastinum, limit its motion, protect it from infection and trauma, lubricate it, and prevent excessive dilation in cases of acute volume overload. Conditions that can affect the pericardium include pericarditis, pericardial effusion, and constrictive pericarditis.
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The pericardium prevents excessive dilation of the heart and protects it from infection
The pericardium is a membrane that surrounds the heart and the roots of the major blood vessels. It is made up of two layers: the fibrous pericardium and the serous pericardium. The fibrous pericardium is the tough, outermost layer of the pericardium, consisting of dense and loose connective tissue. The serous pericardium, on the other hand, is the inner layer, made up of two parts: the parietal serous pericardium and the visceral serous pericardium.
One of the important functions of the pericardium is to prevent excessive dilation of the heart. The fibrous pericardium, with its semi-rigid and non-pliable nature, helps to limit the heart's expansion and prevent excessive distension. This protective function ensures that the heart does not expand too much or fill with too much blood, maintaining its optimal size and shape for proper functioning.
The pericardium also acts as a barrier to protect the heart from infection. Its fibrous layer, made of strong and inelastic connective tissue, forms a protective covering around the heart. This layer helps to separate the heart from interference by other structures and shields it from external pathogens and potential sources of infection.
Additionally, the pericardium provides lubrication to the heart. The serous pericardium layer produces pericardial fluid, which fills the space between the two layers of the pericardium. This fluid reduces friction between the layers, allowing the heart to contract and beat smoothly without any obstruction. The lubrication provided by the pericardial fluid further enhances the protection of the heart by minimising the impact of external forces and shocks.
In summary, the pericardium plays a crucial role in maintaining the health and functionality of the heart. By preventing excessive dilation, the pericardium ensures the heart maintains its optimal size and shape. Its protective structure, particularly the fibrous layer, shields the heart from infections and external trauma. Moreover, the lubrication provided by the pericardial fluid reduces friction during heart contractions, further safeguarding the heart and facilitating its smooth and efficient functioning.
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Pericardial disease can occur as an isolated process or as a symptom of another disease
The pericardium is a double-layered, fibroelastic sac surrounding the heart and the roots of the great vessels. It has an outer layer of fibrous pericardium made of strong inelastic connective tissue and an inner layer of serous pericardium, a serous membrane. The pericardium's basic function is to lubricate the heart's movements and protect it from infection, interference by other structures, and blunt trauma.
Pericardial disease, or pericarditis, is an inflammation of the pericardial sac surrounding the heart. It can occur as an isolated process or as a symptom of another disease. Pericarditis is the most common pathological condition affecting the pericardium. It is often caused by a viral or bacterial infection, or more rarely, by a myocardial infarction. Pericarditis can also be caused by an autoimmune disease, such as lupus or rheumatoid arthritis, or by injury to the chest. In some cases, it may be a result of the body's response to a procedure or condition, such as open-heart surgery, radiation therapy, or cardiac catheterization.
Pericardial disease can manifest in several ways, including acute, incipient or subacute, chronic, and recurrent pericarditis. Acute pericarditis is a common disorder characterised by sudden chest pain that spreads to the back and is exacerbated by inspiration. Recurrent pericarditis is frequent in patients receiving corticosteroid therapy. In some cases, pericarditis can become a long-term condition, causing scarring of the pericardium and restricting the heart's movement, a condition known as constrictive pericarditis.
The diagnosis and management of pericardial disease involve various tests and treatments. First-level tests include complete blood counts, basic metabolic panels, and liver function tests. More advanced testing options include CT scans, cardiac CT, and MRI. Treatment for pericardial disease depends on the underlying cause and can include painkillers, anti-inflammatories, colchicine, and steroid medications. In severe cases of constrictive pericarditis, surgical removal of the pericardium, known as a pericardiectomy, may be necessary.
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Frequently asked questions
The pericardium is a double-walled sac that contains the heart and the roots of the great vessels. It has two layers: an outer layer made of strong inelastic connective tissue (fibrous pericardium) and an inner layer made of serous membrane (serous pericardium).
The pericardium separates the heart from interference of other structures, protects it against infection and blunt trauma, and lubricates the heart's movements. It also sets the heart in mediastinum and limits its motion, prevents excessive dilation in cases of acute volume overload, and equalizes hydrostatic, inertial, and gravitational forces to maintain the geometry of the left ventricle.
Pericarditis is the inflammation of the pericardium, which typically causes chest pain that spreads to the back and is worsened by lying flat. It is often caused by a viral or bacterial infection, or it may occur following a myocardial infarction.

































