Understanding Esophageal Spasms: Causes And Triggers

what causes muscle spasms in the esophagus

Esophageal spasms are abnormal contractions of the muscles in the esophagus, the tube that carries food and drink from the mouth to the stomach. These spasms may not move food and drink effectively to the stomach, causing symptoms such as regurgitation, difficulty swallowing, and chest pain. While the exact cause of esophageal spasms is unknown, they are believed to be related to faulty nerve signalling that controls the muscles used for swallowing. Certain triggers such as specific foods and drinks, stress, and extreme temperatures can also contribute to esophageal spasms. Treatment options include medication, lifestyle changes, and in severe cases, surgery.

Characteristics Values
Definition Abnormal contractions of the muscles in the esophagus, the tube that carries food from the mouth to the stomach.
Symptoms Difficulty swallowing, chest pain, heartburn, regurgitation, a feeling of food being stuck in the throat.
Causes Faulty nerve signaling, nerve problems, excess acid in the esophagus, gastroesophageal reflux disease (GERD), depression, certain foods and drinks (including red wine, spicy food, and very hot or cold liquids), stress, exercise, opioid use.
Risk Factors Age (people between 60 and 80 are at the highest risk), history of esophageal spasm.
Diagnosis Esophageal manometry, barium swallow, endoscopy, esophageal pH monitoring, EKG, stress test, cardiac test.
Treatment Medication (e.g., peppermint oil, calcium channel blockers, antidepressants, proton pump inhibitors), botulinum injections, peroral endoscopic myotomy (POEM), Heller myotomy, lifestyle changes (e.g., avoiding triggers, adjusting food temperatures, reducing stress, eating smaller meals).

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Faulty nerve signalling

Esophageal spasms are abnormal contractions of the muscles in the oesophagus, the tube that connects the mouth to the stomach and transports food and drink. These spasms can be painful and make it difficult for food or liquid to reach the stomach. While the exact cause of esophageal spasms is not known, faulty nerve signalling is believed to play a role in the development of this condition.

Nerve signals from the brain tell the muscles in the oesophagus to contract when swallowing. Faulty nerve signalling can cause these contractions to become uncoordinated, hindering the passage of food and drink instead of aiding it. This can result in regurgitation, where swallowed food or liquid comes back up the oesophagus.

While the exact cause of oesophageal spasms is not fully understood, faulty nerve signalling is believed to be a contributing factor. This can lead to uncoordinated muscle contractions, causing pain and difficulty swallowing. Identifying triggers, such as certain foods and stress, and making lifestyle changes can help manage the condition.

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Stress and anxiety

Esophageal spasms are sudden muscle contractions in the esophagus, the muscular tube that connects your mouth to your stomach. These spasms can cause food or liquid to come back up your esophagus, a condition known as regurgitation. While the exact cause of esophageal spasms is not known, they are believed to be related to abnormal functioning of the nerves that control the muscles used for swallowing.

Anxiety can cause hypersensitivity, making individuals more likely to notice every negative feeling in their body. This heightened awareness can lead to a perception of esophageal problems without any actual changes in the health of the esophagus. For example, individuals with anxiety may feel hyperaware of food travelling down their esophagus, almost like it's stuck, even though there is no physical change.

Additionally, anxiety can exacerbate acid reflux symptoms. While anxiety does not create acid reflux, it can increase stomach acid levels, leading to more severe gastroesophageal reflux disorder (GERD) symptoms. This increase in stomach acid and reflux can further contribute to esophageal spasms.

To manage esophageal spasms related to stress and anxiety, it is crucial to address the underlying stress and anxiety. This can be achieved through relaxation techniques, increased sleep, and avoiding caffeine. Additionally, identifying and avoiding specific food and beverage triggers can help prevent esophageal spasms.

In summary, stress and anxiety can contribute to esophageal spasms by activating the body's stress response, leading to muscle tightening and heightened awareness of bodily sensations. Additionally, anxiety can exacerbate acid reflux, further aggravating esophageal spasms. Effective management of esophageal spasms involves addressing stress and anxiety through relaxation techniques and lifestyle modifications.

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Acid reflux (GERD)

Acid reflux, or gastroesophageal reflux disease (GERD), is a commonly diagnosed chronic condition that occurs when stomach acid flows back up into the oesophagus. This can cause heartburn and other symptoms such as chest pain, a sore throat, bad breath, and nausea. The condition can be diagnosed by a gastroenterologist through tests such as an esophagram, upper endoscopy, oesophageal pH test, and oesophageal manometry.

GERD is characterised by the weakening or relaxation of the lower oesophageal sphincter (LES), a circular muscle that usually keeps substances in the stomach from coming back up. The LES opens when swallowing and closes again, but in people with GERD, it relaxes frequently, allowing acid to pass. This can be influenced by various factors, including dietary and lifestyle habits, such as lying down after a large meal, alcohol consumption, and tobacco use.

GERD is associated with an increased risk of oesophageal cancer, particularly when left untreated. Barrett's oesophagus, a precancerous condition, can develop, increasing the risk of oesophageal cancer by approximately 30 times.

In addition to lifestyle modifications, medication is often recommended to manage GERD. Over-the-counter drugs such as antacids, H-2-receptor blockers, and proton pump inhibitors (PPIs) are commonly used to neutralise or suppress stomach acid. However, long-term acid reflux may require further interventions, such as POEM (a minimally invasive treatment) or, in severe cases, myotomy surgery, where an incision is made in the lower oesophagus muscle to stop abnormal contractions.

GERD is linked to esophageal spasms, with many people experiencing both conditions simultaneously. Esophageal spasms are abnormal contractions in the esophageal muscles, causing symptoms such as chest pain and difficulty swallowing. While the exact cause is unknown, it is believed that faulty nerves controlling the esophageal muscles may be a factor, possibly related to excess acid in the esophagus. Treatment options for esophageal spasms include medication, therapy, and, in rare cases, surgery.

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Opioid use

Oesophageal spasms are relatively rare, with the distal form affecting approximately one person per 100,000 each year. However, opioid use for three months or longer has been identified as a potential risk factor. The adverse gastrointestinal effects of opioids have been well-documented, and their impact on oesophageal motility, or movement, has been the subject of several studies. These studies have found that opioids can affect the lower oesophageal sphincter, leading to disorders such as achalasia and functional EGJ obstruction.

The specific mechanism by which opioids cause oesophageal spasms is believed to involve the enteric nervous system and opium receptors in the central and enteric nervous systems. In particular, the μ, δ, and κ receptors have been implicated in mediating the gastrointestinal effects of opioids. While constipation has been the most studied adverse gastrointestinal effect, recent research has turned its attention to the impact of opioids on the oesophagus.

Oesophageal spasms related to opioid use often resolve once the opioids are discontinued. However, in some cases, pneumatic dilation or surgical intervention may be necessary to treat severe dysphagia, or difficulty swallowing. Overall, while the link between opioid use and oesophageal spasms is not yet fully understood, the available research suggests that long-term opioid use may increase the risk of developing oesophageal spasms, and discontinuing opioid use may help alleviate these spasms.

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Food and drink triggers

  • Very hot or very cold foods and drinks.
  • Spicy food.
  • Meat, dry bread and rice—if the spasm also causes trouble swallowing.

Some other food and drink-related triggers that may help are:

  • Jotting down the temperature and quantity of food and drink.
  • Including hidden ingredients, like spices, in the food diary.
  • Taking standardised deglycyrrhizinated licorice (DGL) extract an hour or two before or after meals.
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Frequently asked questions

Esophageal spasms are abnormal contractions of the muscles in the esophagus, the tube that carries food from the mouth to the stomach. These spasms may not move food effectively to the stomach.

The exact cause of esophageal spasms is unknown. However, some believe they occur due to faulty nerve signals from the brain that control how the esophageal muscles contract. Certain foods and drinks, stress, and acid reflux (GERD) may also be triggers.

Treatment options for esophageal spasms include medication, lifestyle changes, home remedies, and in severe cases, surgery. Medications aim to relax the smooth muscle of the esophagus, and peppermint oil or lozenges are often recommended as a natural muscle relaxant. Identifying and avoiding food and drink triggers can also help manage esophageal spasms.

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