
The cricopharyngeus muscle is a crucial component of the upper esophageal sphincter (UES), which acts as a protective valve between the throat and the esophagus. This muscle is typically contracted, safeguarding the airway and lungs from any stomach contents that might flow back up through the esophagus. During swallowing, the cricopharyngeus muscle relaxes, allowing food and liquids to pass through to the esophagus. Dysfunction of this muscle can lead to swallowing difficulties, and in some cases, more severe symptoms such as weight loss or aspiration of food. Treatment options for cricopharyngeus muscle dysfunction include dilation, oral medications, BOTOX injections, and myotomy.
| Characteristics | Values |
|---|---|
| Location | Junction of the pharynx (throat) and esophagus |
| Function | Protects the airway and lungs from damaging stomach contents that might be refluxed up through the esophagus into the throat |
| Function | Allows food, liquid, and saliva to enter the esophagus by relaxing while these contents pass through |
| Dysfunction | Causes difficulty swallowing |
| Dysfunction | Can cause pharyngeal dysphagia |
| Treatment | Cricopharyngeus muscle myotomy |
| Treatment | Balloon dilation |
| Treatment | Oral medications |
| Treatment | Botox injection |
| Treatment | Botox injection |
| Length | 3-5 cm |
| Innervation | Recurrent laryngeal nerve |
| Innervation | External branch of the superior laryngeal nerve |
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What You'll Learn
- The cricopharyngeus muscle is a component of the upper esophageal sphincter
- It relaxes to allow food to pass from the pharynx to the oesophagus
- Cricopharyngeal dysfunction can cause difficulty swallowing
- Treatments include balloon dilation and cricopharyngeus myotomy
- The muscle is innervated by the recurrent laryngeal nerve

The cricopharyngeus muscle is a component of the upper esophageal sphincter
The cricopharyngeus muscle is a crucial component of the upper esophageal sphincter (UES). Located at the junction of the pharynx (throat) and oesophagus, it is a striated muscle that plays a protective role by preventing refluxed stomach contents from entering the throat and lungs.
The UES, of which the cricopharyngeus muscle is a major part, acts as a valve that separates the oesophagus and throat. In a healthy state, the UES remains tightly closed at rest, only relaxing during the act of swallowing to allow ingested food, liquids, and saliva to pass through into the oesophagus. This coordinated relaxation of the cricopharyngeus muscle is essential for normal swallowing.
Cricopharyngeus muscle dysfunction (CPD) occurs when this relaxation or expansion fails to occur properly. CPD can manifest as cricopharyngeal dysfunction, characterised by symptoms such as difficulty swallowing, a sensation of food sticking in the neck, and in severe cases, weight loss or aspiration of food. CPD can result from various conditions, including muscle enlargement, scarring from radiation therapy or trauma, stroke, and reflux.
Diagnosis of CPD involves a combination of clinical and instrumental swallowing evaluations. Flexible endoscopic evaluation of swallowing, video-fluoroscopic swallow studies, and high-resolution manometry are commonly used techniques to assess swallowing function and identify any abnormalities in the cricopharyngeus muscle.
Treatment options for CPD aim to improve swallowing ability and quality of life. These treatments include non-surgical interventions such as pharyngoesophageal segment dilation, botulinum toxin injection, and cricopharyngeus myotomy, a procedure where the UES is cut to prevent over-tightening and obstruction. The choice of treatment depends on the specific symptoms and underlying causes of the dysfunction.
In summary, the cricopharyngeus muscle, as a key component of the UES, plays a vital role in protecting the airway and facilitating the swallowing process. Dysfunction of this muscle can lead to significant health issues, but accurate diagnosis and a range of treatment options are available to manage and improve this condition.
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It relaxes to allow food to pass from the pharynx to the oesophagus
The cricopharyngeus muscle is a crucial component of the upper oesophageal sphincter (UES), which acts as a protective valve between the pharynx (throat) and oesophagus. When at rest, the UES remains tightly closed, preventing food or liquid from entering the lungs. This protective mechanism is essential for safeguarding the lungs from potentially harmful stomach contents that may travel upwards through the oesophagus.
The cricopharyngeus muscle plays a critical role in the act of swallowing. When food is ingested, the cricopharyngeus muscle relaxes and opens, allowing the swallowed food to pass from the pharynx into the oesophagus. This relaxation is a carefully coordinated process, ensuring that food can safely transit into the oesophagus without entering the airway.
Cricopharyngeus muscle dysfunction (CPD) can occur when this relaxation or expansion of the muscle fails to occur properly. CPD can manifest as pharyngeal dysphagia, a sensation of food getting stuck in the neck shortly after swallowing. In severe cases, patients may experience weight loss or even aspiration of food that remains lodged in the pharynx.
Diagnosing CPM and UES dysfunction typically involves a range of tests performed by an ear, nose, and throat (ENT) specialist or otolaryngologist. These tests may include an endoscopic examination, where a small flexible camera is passed through the nose to visualise the throat and larynx. Additionally, an X-ray swallowing test, known as a modified barium swallow or Videofluoroscopic Swallow Study (VFSS), may be utilised to observe the transit of barium-coated food, liquid, and pills through the oesophagus.
Treatment options for CPM dysfunction aim to improve swallowing ability and quality of life. These treatments include dilation procedures, oral medications, botulinum toxin (Botox) injections, and cricopharyngeus myotomy, a procedure where the UES is cut to prevent over-tightening and obstruction. The choice of treatment depends on the specific symptoms and the underlying cause of the dysfunction.
In summary, the cricopharyngeus muscle is a vital component of the UES, responsible for protecting the airway during swallowing. Its relaxation allows ingested food to pass safely from the pharynx to the oesophagus, while any dysfunction in this muscle can lead to swallowing difficulties and potentially impact an individual's health and quality of life.
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Cricopharyngeal dysfunction can cause difficulty swallowing
The cricopharyngeus muscle is a major muscular component of the upper esophageal sphincter (UES). During swallowing, the cricopharyngeus muscle typically relaxes, allowing food and liquids to pass from the throat (pharynx) into the oesophagus. However, cricopharyngeal dysfunction can cause difficulty swallowing, or pharyngeal dysphagia, due to the muscle's inability to relax. This can result in food getting stuck in the neck, causing choking episodes and anxiety about eating.
Cricopharyngeal dysfunction can be caused by muscular, neurological, or degenerative conditions, as well as muscle enlargement (hypertrophy), scarring, stroke, or reflux (heartburn). Diagnosis can be obtained through a combination of clinical and instrumental swallowing evaluations, including a videofluoroscopic swallow study, manometry, and endoscopic examination. Treatment options include dilation (stretching), Botox injections, and cricopharyngeal myotomy (cutting the muscle).
Dilation is a minimally invasive procedure that uses a balloon catheter to stretch the oesophagus and increase the opening. This procedure can significantly improve symptoms for about six months but may need to be repeated as it is not a permanent solution. Botox injections can also help relax or partially paralyse the upper oesophageal sphincter, but they only work for some causes of cricopharyngeal dysfunction and typically last for three to six months.
Cricopharyngeal myotomy is considered the definitive treatment for cricopharyngeal dysfunction. It can be performed in a minimally invasive manner using a laser manipulated through the mouth, or through a small incision made in the neck. This procedure cuts the muscle to prevent over-contraction, allowing food and liquids to pass through easily. Myotomy is generally considered a permanent solution and has been shown to provide significant improvement in swallowing and quality of life.
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Treatments include balloon dilation and cricopharyngeus myotomy
The cricopharyngeus muscle is located at the junction of the pharynx (throat) and oesophagus. It is the major muscular component of the upper oesophageal sphincter (UES). When something is swallowed, the cricopharyngeus relaxes and opens, allowing food to pass from the pharynx into the oesophagus.
Cricopharyngeal dysfunction can cause a variety of symptoms, including heartburn, regurgitation of stomach contents into the mouth, and difficulty swallowing. Treatments for this dysfunction include balloon dilation and cricopharyngeus myotomy.
Balloon Dilation
This is a minimally invasive procedure used to stretch the muscle and allow food and liquid to pass. A catheter with a balloon at the end is passed through the mouth and into the oesophagus. The balloon is then inflated to enlarge the opening. This procedure can significantly improve symptoms for about six months and may be repeated as needed.
Cricopharyngeus Myotomy
Cricopharyngeus myotomy is a surgical procedure that involves cutting the cricopharyngeus muscle to prevent it from over-tightening and blocking food from entering the oesophagus. This can be done through an incision in the neck or via an endoscopic approach, which is less invasive and has fewer associated risks. The endoscopic procedure is performed by introducing a laser through the mouth. Cricopharyngeus myotomy is generally recommended for patients with moderate to severe dysphagia and related complications such as weight loss and pneumonia.
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The muscle is innervated by the recurrent laryngeal nerve
The cricopharyngeus muscle is a crucial component of the upper esophageal sphincter (UES), located at the junction of the pharynx (throat) and oesophagus. It acts as a protective mechanism by remaining tightly closed at rest, preventing food or liquid from entering the lungs. During swallowing, the muscle relaxes, allowing ingested substances to pass through to the oesophagus. This process is facilitated by the recurrent laryngeal nerve, which innervates the cricopharyngeus muscle.
The recurrent laryngeal nerve plays a vital role in the proper functioning of the cricopharyngeus muscle. This nerve is responsible for sending signals to the muscle, prompting it to relax during swallowing. When the cricopharyngeus muscle receives the signal from the nerve, it relaxes and opens, enabling the passage of food or liquid from the pharynx into the oesophagus. This coordination between the nerve and the muscle ensures that swallowing occurs smoothly and safely.
Dysfunction of the cricopharyngeus muscle, known as cricopharyngeus muscle dysfunction (CPD), can occur when there is a failure in the coordinated relaxation or expansion of the muscle. CPD can lead to swallowing difficulties, such as pharyngeal dysphagia, where individuals experience the sensation of food getting stuck in their neck shortly after swallowing. In some severe cases, CPD may result in weight loss or aspiration of food into the lungs.
The accurate diagnosis of CPD is essential for effective treatment. A combination of clinical evaluations, including flexible endoscopy, evaluation of swallowing, video-fluoroscopic swallow studies, and high-resolution manometry, can be utilised to diagnose CPD. Treatment options for CPD include nonsurgical interventions such as pharyngoesophageal segment dilation, botulinum toxin injection, and cricopharyngeus myotomy. Dilation procedures aim to stretch the muscle and can be performed using balloon dilation or Savary dilators. Cricopharyngeus myotomy, a more permanent solution, involves cutting the muscle to prevent over-tightening and blocking food from entering the oesophagus.
The recurrent laryngeal nerve is integral to the proper functioning of the cricopharyngeus muscle, and any impairment of this nerve can lead to swallowing difficulties. For example, patients with recurrent laryngeal nerve (RLN) paresis exhibit impaired function of laryngeal muscles and swallowing. Thus, the health and proper functioning of the recurrent laryngeal nerve are crucial to maintaining the normal swallowing mechanism facilitated by the cricopharyngeus muscle.
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Frequently asked questions
The cricopharyngeus muscle is located at the junction of the pharynx (throat) and oesophagus. It is the major muscular component of the upper oesophageal sphincter (UES).
The cricopharyngeus muscle is responsible for protecting the airway and lungs from stomach contents that might be refluxed up through the oesophagus into the throat. When something is swallowed, the muscle relaxes and opens, allowing food and liquid to pass through the pharynx into the oesophagus.
Cricopharyngeal dysfunction occurs when the cricopharyngeus muscle malfunctions or is impaired. This can cause difficulty swallowing, or dysphagia.
Treatment options for cricopharyngeal dysfunction include dilation (stretching), oral medications, BOTOX® injection, and myotomy (cutting).










































