
The intercostal nerves are part of the somatic nervous system, aiding in the contraction of muscles and the return of sensory information from the skin and parietal pleura. They are mixed nerves, carrying motor and sensory fibers. Their main function is to provide segmental supply to the structures of the thoracic wall and abdominal wall. The intercostal nerves arise from the anterior rami of the thoracic spinal nerves from T1 to T11 and are situated between adjacent ribs. The intercostal neurovascular structures travel through the intercostal space between the pleura and intercostal membrane. The intercostal nerves are in constant danger of being damaged during thoracotomy procedures or chest tube placement.
| Characteristics | Values |
|---|---|
| Type of nerve | Mixed nerve, carrying motor and sensory fibers |
| Origin | Thoracic spinal nerves from T1 to T11 |
| Main function | Provide segmental supply to the structures of the thoracic wall and abdominal wall |
| Innervation | Motor innervation for intercostal muscles, and muscles of the anterolateral abdominal wall |
| Sensory innervation | Carry sensory afferents from the skin of the thoracic and abdominal wall, ribs, pleura, and peritoneum |
| Sympathetic innervation | Structures of the thoracic and abdominal walls, such as sweat glands and blood vessels |
| Number of pairs | 11 pairs of external intercostal muscles |
| Direction | Run inferoanteriorly from the rib above to the rib below |
| Attachments | Originate at the lower border of each rib, inserting onto the superior border of the rib below |
| Actions | Stabilize the position of the ribs during normal respiration, elevate the ribs, and increase thoracic volume during forced inspiration |
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What You'll Learn

Intercostal nerve structure and function
Intercostal nerves are part of the somatic nervous system, aiding in muscle contraction and the return of sensory information from the skin and parietal pleura. They arise from the anterior rami of the thoracic spinal nerves from T1 to T11 and are situated between adjacent ribs. The anterior division of the twelfth thoracic nerve is not an intercostal nerve as it sits below the ribs to enter the abdominal wall; this is instead referred to as the subcostal nerve.
The intercostal nerves are mixed nerves, carrying motor and sensory fibres. Their main function is to provide segmental supply to the structures of the thoracic wall and abdominal wall. They carry sensory afferents from the skin of the thoracic and abdominal wall, ribs, pleura, and peritoneum. These nerves also carry sympathetic innervation to structures such as sweat glands and blood vessels of the thoracic and abdominal walls.
The intercostal nerves give off several branches: muscular branches for the intercostal muscles, subcostal muscles, serratus posterior superior, levatores costarum, and transversus thoracis muscles. The cutaneous branches are the lateral cutaneous branches, which further divide into anterior and posterior branches, and the anterior cutaneous branches, which also divide into medial and lateral branches. These branches supply segmental sensory innervation to the skin of the anterolateral walls of the thorax and abdomen. The collateral branches arise close to the angles of the ribs and course along the superior border of the inferior rib to innervate the intercostal muscles, parietal pleura, and the periosteum of the rib. The communicating branches (rami communicantes) connect each intercostal nerve to the ipsilateral sympathetic trunk.
The typical intercostal nerves (IC) include IC3 to IC6, while the atypical intercostal nerves include IC1, IC2, and IC7 to IC11. The typical intercostal nerves stay confined to their own intercostal spaces, while the atypical spinal nerves go beyond the thoracic wall to supply other regions. The lateral cutaneous branch of the second intercostal nerve is known as the intercostobrachial nerve, which supplies the floor of the axilla and upper posteromedial region of the upper extremity.
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Intercostal nerve pain
Intercostal neuralgia can manifest in various ways, including sharp, stabbing, burning, or aching sensations in the affected areas. It may also be accompanied by tingling and numbness, and in severe cases, reduced motor function. The pain can be constant or intermittent and is often influenced by factors such as physical activity or unexpected movements, like coughing, sneezing, or even breathing.
The causes of intercostal neuralgia are diverse, but some of the most common include tissue and nerve irritation after a thoracotomy, a surgical procedure involving an incision between the ribs to access the lungs or heart. This can lead to post-thoracotomy pain syndrome (PTPS), which affects about 50% of individuals who undergo this surgery. Additionally, the reactivation of a herpes zoster (HZ) or shingles infection can contribute to intercostal neuralgia by causing inflammation in the spinal nerve roots.
Pregnancy can also be a factor in the development of intercostal neuralgia due to the profound bodily changes that can impact the spinal cord and nerves. Other potential causes include traumatic injuries, chest tube placement, mastectomy, breast surgery, anatomical compression, inflammatory processes, and diabetic peripheral neuropathy.
The treatment for intercostal neuralgia depends on the severity of symptoms, the patient's medical history, and their preferences. A combination of treatments may be necessary for effective pain management. Some common approaches include antidepressants, nerve blocks to inject steroids and pain-relieving medicine, thoracic epidural, and dorsal root ganglion pulsed radiofrequency. Over-the-counter options such as capsaicin creams, lidocaine gel, or lidocaine patches may also provide some relief.
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Intercostal nerve damage
The intercostal muscles are innervated by the intercostal nerves, which arise from the thoracic nerves (T1 to T11) and run between the ribs. Damage to these nerves can result in a range of symptoms and complications due to the important role they play in the functioning of the respiratory system and the protection of the thoracic organs.
The damage to the intercostal nerves can lead to impaired breathing and respiratory dysfunction. The intercostal muscles play a crucial role in the mechanics of breathing, and their paralysis or weakness can result in reduced chest expansion and shallow breathing. This can further cause respiratory complications such as pneumonia or respiratory failure. Additionally, patients may experience difficulties in coughing and clearing secretions from the lungs, increasing the risk of respiratory infections.
Another significant consequence of intercostal nerve damage is the potential impairment of the thoracic organs' protection. The intercostal muscles provide structural support and protection to the chest cavity. Weakness or paralysis of these muscles can result in decreased chest wall stability, making individuals more susceptible to injuries and increasing the risk of complications from blunt force trauma to the chest.
Treatment for intercostal nerve damage aims to address the underlying cause, manage symptoms, and improve respiratory function. In cases of physical trauma, surgical intervention may be required to repair damaged nerves or stabilize the chest wall. Rehabilitation often involves respiratory physiotherapy to improve lung function and strengthen the diaphragm and other respiratory muscles to compensate for the weakened intercostal muscles.
The prognosis for intercostal nerve damage varies depending on the severity of the injury and the success of treatment interventions. While some patients may recover partially or fully, others may experience persistent symptoms and long-term respiratory complications. Early diagnosis and appropriate management are crucial for optimizing outcomes and minimizing the impact of this condition on respiratory function and overall quality of life.
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Intercostal nerve branches
The intercostal nerves are part of the somatic nervous system, aiding in the contraction of muscles and the return of sensory information from the skin and parietal pleura. They carry motor and sensory fibres, providing segmental supply to the structures of the thoracic wall and abdominal wall.
The intercostal nerves arise from the anterior rami of the thoracic spinal nerves from T1 to T11. The anterior division of the twelfth thoracic nerve is not technically an intercostal nerve as it sits below the ribs to enter the abdominal wall; this nerve is instead referred to as the subcostal nerve. The intercostal nerves are distributed chiefly to the thoracic pleura and abdominal peritoneum.
The intercostal nerve is directly external to the parietal pleura and then dives into the subcostal groove of its associated rib, which lies directly inferior to the rib. As it runs its course through the subcostal groove, the nerve is bounded by the innermost intercostal muscle and the internal intercostal muscle. The first six intercostal nerves give off branches and then end within the corresponding intercostal space just below the corresponding rib.
The intercostal nerve branches include the muscular branches, cutaneous branches, collateral branches, and communicating branches (rami communicantes). The muscular branches supply the intercostal muscles, subcostal muscles, serratus posterior superior, levatores costarum, and transversus thoracis muscles. The cutaneous branches are the lateral cutaneous branches, which further divide into anterior and posterior branches, and the anterior cutaneous branches, which also divide into medial and lateral branches. These branches supply segmental sensory innervation to the skin of the anterolateral walls of the thorax and abdomen. The lateral cutaneous branch of the second intercostal nerve is known as the intercostobrachial nerve, which supplies the floor of the axilla and upper posteromedial region of the upper extremity. The collateral branches arise close to the angles of the ribs and course along the superior border of the inferior rib to innervate the intercostal muscles, parietal pleura, and the periosteum of the rib. The communicating branches connect each intercostal nerve to the ipsilateral sympathetic trunk.
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Intercostal nerve innervation
Intercostal nerves are part of the somatic nervous system, providing sensory and motor innervation to the thoracic and abdominal walls. They are mixed nerves, carrying motor and sensory fibres. The intercostal nerves are the anterior rami of the first eleven thoracic spinal nerves, from T1 to T11. Each intercostal nerve enters the intercostal space between the posterior intercostal membrane and the parietal pleura, travelling along the inferior border of the corresponding rib.
The intercostal nerves provide segmental supply to the structures of the thoracic wall and abdominal wall. They carry sensory afferents from the skin of the chest and abdominal wall, as well as the ribs, pleura, and peritoneum. The sensory innervation of the intercostal nerves is to the skin of the chest and abdomen. They also carry sympathetic innervation to structures such as sweat glands and blood vessels of the thoracic and abdominal walls.
The motor innervation of the intercostal nerves is to the intercostal and abdominal wall muscles. The muscular branches of the intercostal nerves supply the intercostal muscles, subcostal muscles, serratus posterior superior, levatores costarum, and transversus thoracis muscles. The intercostal nerves also provide motor innervation to the external and internal abdominal oblique, transversus abdominis, and rectus abdominis muscles.
The lateral cutaneous branch of the second intercostal nerve is known as the intercostobrachial nerve, which supplies the axilla and upper extremity. The intercostobrachial nerve is also associated with cardiac referred pain in acute cases of coronary artery disease. The anterior cutaneous branches of the intercostal nerves supply the skin of the anterior thoracic wall.
The intercostal nerves are at risk of damage during thoracotomy procedures and chest tube placement. They can be used for nerve transfers and may be an option for donor nerves, especially in reconstructing the long thoracic nerve.
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Frequently asked questions
Intercostal nerves are part of the somatic nervous system, carrying motor and sensory fibers. They provide sensory input from the chest and abdominal walls and motor innervation to the intercostal and abdominal muscles.
The intercostal nerves T1-T11 innervate the intercostal muscles.
The intercostal muscles, along with the subcostales, serratus posterior superior, and transversus thoracis, act to change the thoracic volume during breathing.
If an intercostal nerve is damaged, it can cause pain, sensation loss, and/or weakness in the areas of the body supplied by that nerve.











































