
Eliquis is a brand-name medication that comes in the form of a tablet that is swallowed. It is prescribed to treat and help prevent blood clots and is commonly referred to as a blood thinner. While Eliquis is an effective medication, it can cause mild or serious side effects. These include bleeding, the risk of spinal blood clots, and in rare cases, muscle weakness. If you experience any side effects after beginning Eliquis, it is important to contact your healthcare provider.
| Characteristics | Values |
|---|---|
| Muscle weakness | Rare side effect |
| Leg weakness | Rare side effect |
| Risk of spinal blood clots | Common side effect |
| Risk of stroke | May increase if Eliquis is stopped abruptly |
| Risk of intracranial and intracerebral haemorrhage | Rare side effect |
| Risk of paralysis | Rare side effect |
| Risk of depression | Not conclusively linked |
| Risk of increased Eliquis levels in the body | May be caused by grapefruit juice |
| Muscle twitches and cramps | May be caused by oxygen starvation due to blood clots |
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What You'll Learn

Eliquis may cause muscle weakness in the legs
Eliquis is a brand-name medication that comes in the form of a tablet that you swallow. It is a popular anticoagulant drug, also known as a blood thinner, used to treat and help prevent blood clots. It is important to note that Eliquis may cause mild or serious side effects, and these can vary from person to person.
While rare, muscle weakness in the legs has been reported as a possible side effect of Eliquis. Some people have shared their experiences online, stating that they experienced leg muscle weakness within a month of starting Eliquis. They reported that their leg muscles became weak to the point where they could no longer participate in certain physical activities or walk for extended periods.
It is important to consult your doctor if you experience any side effects, especially if they are bothersome or do not go away. In some cases, individuals have reported an improvement in leg strength after discontinuing Eliquis, but it is crucial to speak to your doctor before making any changes to your medication.
Additionally, Eliquis has a boxed warning about the risk of spinal blood clots, which can lead to long-term or permanent paralysis. This risk is increased if you have an epidural catheter in your back, take certain other medications, have a history of epidural punctures, or have had spine problems or surgery. Therefore, it is essential to notify your doctor immediately if you experience any signs of nerve problems, such as back pain, numbness, tingling, or muscle weakness, especially in your legs and feet.
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Eliquis is a blood thinner used to prevent blood clots
Eliquis is a prescription anticoagulant drug, also known as a blood thinner, used to prevent and treat blood clots. It is typically prescribed to adults to prevent blood clots and strokes in people with a type of irregular heartbeat called atrial fibrillation (AFib). AFib is a condition where the patient has an increased risk of blood clots forming in their heart. Eliquis contains the active ingredient apixaban, which blocks the substances in the blood from forming blood clots.
Eliquis is available as an oral tablet and is typically taken twice a day. The dosage depends on the patient's condition and can vary between 2.5 mg to 5 mg per dose. It is important to take Eliquis as prescribed and not stop taking it without consulting a healthcare provider, as stopping Eliquis can increase the risk of blood clots or strokes.
While Eliquis is effective in preventing blood clots, it can also cause certain side effects. The most common side effect is bleeding, which can lead to easy bruising and prolonged bleeding. Other common side effects include anemia, haemorrhage, nausea, and increased blood glucose levels. In rare cases, Eliquis may cause major bleeding in the head, known as intracranial and intracerebral haemorrhage, which can result in long-term complications and disabilities.
In addition to these side effects, there have been reports of muscle weakness and leg weakness in patients taking Eliquis. However, these side effects are considered rare, and there is conflicting evidence regarding their occurrence. While some patients have experienced significant leg muscle weakness, others have reported no muscle weakness at all while taking Eliquis. It is important to note that leg weakness can also be a symptom of a spinal blood clot, which is a rare but serious side effect of Eliquis. Patients experiencing any numbness or weakness in their legs or feet while taking Eliquis should consult their healthcare provider immediately.
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The risk of spinal blood clots increases with Eliquis
Eliquis is a brand-name medication that is prescribed to treat and help prevent blood clots. It is also used to prevent deep vein thrombosis (DVT), which could lead to pulmonary embolism (PE). Eliquis is an anticoagulant drug, also known as a blood thinner, that contains apixaban as its active ingredient.
While Eliquis is an effective medication, it does carry the risk of certain side effects, some of which may be mild and temporary, while others can be serious. The risk of experiencing side effects varies from person to person. The most commonly reported side effects of Eliquis include bleeding, anaemia, haemorrhage, nausea, and increased blood glucose levels.
One of the more serious side effects associated with Eliquis is the increased risk of spinal blood clots, particularly in individuals who undergo certain spinal procedures. This risk is emphasised by a boxed warning from the Food and Drug Administration (FDA), indicating its seriousness. Spinal blood clots can lead to long-term or permanent paralysis, especially if an epidural catheter is present, or if there is a history of spinal problems or surgeries.
The risk of spinal blood clots is not limited to spinal procedures. Individuals taking Eliquis who experience symptoms such as tingling, numbness, or muscle weakness, especially in the legs and feet, may be at risk of spinal blood clots. These symptoms could also indicate nerve issues caused by oxygen starvation due to the presence of blood clots. Therefore, it is crucial to notify your doctor immediately if you experience any of these symptoms while taking Eliquis.
While muscle weakness is a rare side effect of Eliquis, there are reports of individuals experiencing leg muscle weakness to the extent that it interferes with their daily activities. In some cases, discontinuing Eliquis has led to significant improvements in leg strength. However, it is important to note that abruptly stopping Eliquis without medical advice can increase the risk of stroke.
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Eliquis may cause mild or serious side effects
Eliquis is a brand-name medication prescribed to treat and help prevent blood clots. It is a popular blood thinner that can cause mild or serious side effects.
Some people taking Eliquis have reported muscle weakness, specifically in the legs, as a rare side effect. However, this was not reported in studies of Eliquis. In addition, some patients have reported experiencing no side effects at all. It is important to note that muscle weakness can also be a symptom of a spinal blood clot, which Eliquis may increase the risk of.
The most common side effects of Eliquis include bleeding and the risk of spinal blood clots from certain spinal procedures. Eliquis may also increase the risk of blood clots in the spine or epidural area, which can lead to long-term or permanent paralysis. This risk is heightened in patients who have an epidural catheter in their back, are taking NSAIDs or blood clotting medicine, have a history of repeated epidural punctures or spinal problems, or have had spinal surgery.
Other possible side effects of Eliquis include:
- Anemia
- Hemorrhage
- Nausea
- Hypoglycemia
- Joint pain or swelling
- Chest pain or pressure
- Weakness on one side of the body
- Trouble speaking or thinking
- Change in balance
- Blurred eyesight
- Dizziness or fainting
- Fatigue
- Confusion
- Gout
- Diabetes mellitus
- Increased blood glucose
- Hypokalemia
- Decreased appetite
- Hypersensitivity
- Increased transaminases, AST, ALT, gamma-glutamyl transferase, alkaline phosphatase, or blood bilirubin
- Abnormal liver function tests
- Acid reflux
- Trouble swallowing
- Shortness of breath
- Heavy menstrual cycle
- Itching
- Anxiety
- Elevated heart rate
If you experience any side effects after beginning Eliquis, contact your healthcare provider. Do not stop taking the medication or let your prescription run out, as this can increase your risk of stroke. If you are experiencing painful or disruptive side effects, contact your healthcare provider immediately.
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Consult a doctor before stopping Eliquis
Eliquis is an anticoagulant drug that helps prevent blood clots and reduces the risk of strokes. It is a medication that may cause mild or serious side effects. Some common side effects include an increased risk of bleeding, bruising more easily, and an increased risk of blood clots in or around the spine.
While Eliquis has been linked to muscle weakness in the legs, this is a rare side effect. If you are experiencing leg muscle weakness, it is important to consult a doctor before stopping Eliquis. Stopping Eliquis without medical advice can be dangerous and may increase your risk of blood clots and strokes.
If you are experiencing side effects, your doctor may adjust your dosage or recommend an alternative medication. It is important to note that Eliquis may need to be stopped temporarily before certain medical procedures, but this should always be done under the supervision of a healthcare provider.
Additionally, if you are experiencing any signs of bleeding, such as unusual bleeding from the gums, nosebleeds, or heavier-than-normal menstrual bleeding, seek medical help right away.
It is always recommended to consult a doctor before making any changes to your medication. They will be able to provide personalized advice and ensure that any necessary precautions are taken.
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Frequently asked questions
Eliquis is a blood thinner used to prevent blood clots and has been known to cause rare serious side effects such as muscle weakness. If you experience any side effects, contact your healthcare provider.
The most common side effects of Eliquis include bleeding, anaemia, haemorrhage, and nausea.
Rare side effects of Eliquis include muscle haemorrhage, joint swelling, hypersensitivity, and liver function test abnormalities.
Serious side effects of Eliquis may include bleeding in the head, intracranial haemorrhage, and intracerebral haemorrhage. These can lead to long-term complications and may cause long-term disability.
If you experience any side effects from Eliquis, it is important to notify your healthcare provider. Do not stop taking the medication or let your prescription run out, as this can increase the risk of stroke.


























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