
Jardiance (empagliflozin) is a medication used to treat Type 2 diabetes and heart failure. While it is generally safe and effective, it can cause a range of side effects, from mild to severe. Some of the most common side effects include urinary tract infections (UTIs) and genital yeast infections. In rare cases, Jardiance may also cause serious allergic reactions, including angioedema, which can be life-threatening. It is also associated with an increased risk of lower leg or toe amputation. Additionally, there have been reports of joint pain in some individuals taking Jardiance, although it is unclear if the medication is directly responsible for this side effect.
| Characteristics | Values |
|---|---|
| Can Jardiance cause muscle and joint pain? | In clinical studies, around 2.4% of people who took Jardiance experienced joint pain. However, 2.2% of people who took a placebo also reported joint pain. Therefore, it is unclear if the joint pain was related to Jardiance. |
| What are the side effects of Jardiance? | Jardiance may cause mild or serious side effects. Some of the most common side effects include UTIs, vaginal yeast infections, abdominal pain, nausea, dizziness, lightheadedness, fainting, ketoacidosis, low blood sugar, dehydration, and skin rashes. |
| What should I do if I experience side effects? | If you experience any side effects, consult your doctor or pharmacist. They can provide tips on managing any concerning or bothersome symptoms. |
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What You'll Learn
- Jardiance may cause joint pain, but it's unclear if it's directly responsible
- Jardiance can cause UTIs, which may lead to abdominal pain
- Genital yeast infections are a common side effect, causing pain and swelling
- Ketoacidosis, a serious side effect, can cause abdominal pain
- Jardiance may cause serious allergic reactions, including angioedema

Jardiance may cause joint pain, but it's unclear if it's directly responsible
Jardiance is a medication used to help manage Type 2 diabetes or heart failure. While it is generally safe and effective, it can cause a range of side effects, some of which may be mild and manageable at home, while others can be more serious. One of the possible side effects of Jardiance is joint pain. In clinical studies, around 2.4% of people who took Jardiance experienced joint pain. However, it's important to note that a similar percentage of people (2.2%) who took a placebo also reported joint pain. This suggests that while joint pain may occur with Jardiance use, it's unclear if Jardiance is directly responsible for it.
The exact mechanism behind the joint pain is not well understood, but it's important to monitor and address it if it occurs. If you experience joint pain while taking Jardiance, it is recommended to consult your doctor or healthcare provider. They can evaluate your symptoms, rule out other potential causes, and provide guidance on managing the pain. It's important to remember that side effects can vary from person to person, and individual factors may influence the likelihood and severity of joint pain.
While the link between Jardiance and joint pain is uncertain, the medication has been associated with other side effects that are more clearly established. One of the most common side effects of Jardiance is genital yeast infections, which can affect both men and women. These infections can cause symptoms such as itching, discharge, and redness in the genital area. Additionally, Jardiance may increase the risk of urinary tract infections (UTIs) and more serious infections like necrotizing fasciitis or Fournier's gangrene, a rare but severe bacterial infection affecting the perineum.
It's important to be vigilant about monitoring for these side effects and seeking medical advice if they occur. Other possible side effects of Jardiance include ketoacidosis, a serious complication of diabetes that can lead to life-threatening consequences. Dehydration, low blood pressure, and kidney damage are also potential side effects. Regular medical check-ins and monitoring of cholesterol levels are recommended while taking Jardiance to ensure early detection and management of any adverse effects.
In summary, while Jardiance may be associated with joint pain, the evidence is inconclusive. It is always important to be aware of any changes in your body and to consult your healthcare provider if you have concerns. They can provide personalized advice and help manage any side effects that may arise.
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Jardiance can cause UTIs, which may lead to abdominal pain
Jardiance is a medication used to help manage Type 2 diabetes or heart failure. While it is generally safe and effective, it can cause a number of side effects, including urinary tract infections (UTIs). UTIs are characterised by symptoms such as an increased need to urinate, burning with urination, abdominal pain, bloody urine, fever, back pain, nausea, and vomiting.
Abdominal pain was not a direct side effect reported in clinical studies of Jardiance. However, it could be a symptom of other Jardiance side effects, such as UTIs, as mentioned above. Lower abdominal pain and pelvic pain can be caused by UTIs, and patients should check with their doctor right away if they experience such symptoms.
UTIs are more likely to occur in patients with a history of genital yeast infections or in men who are not circumcised. Women may experience vaginal discharge, itching, or odour, while men may experience redness, itching, swelling, or pain around the penis, or a discharge with a strong odour. These symptoms may indicate a yeast infection, which is another common side effect of Jardiance.
In addition to abdominal pain, UTIs can also cause more serious complications, such as pyelonephritis (a kidney infection) or urosepsis (an untreated urinary tract infection that spreads to the kidney). These infections can be life-threatening and require immediate medical attention. Therefore, it is important for patients taking Jardiance to be aware of the risk of UTIs and to seek medical advice if they experience any potential UTI symptoms.
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Genital yeast infections are a common side effect, causing pain and swelling
Jardiance is a medication used to help manage Type 2 diabetes or heart failure. It is generally safe and effective, but like many medications, it can cause a number of side effects, some of which can be serious. One of the most common side effects of Jardiance is genital yeast infections, which can affect both men and women.
Genital yeast infections occur when there is an overgrowth of yeast in the genital area. In women, this can present as a vaginal yeast infection, with symptoms such as vaginal discharge, itching, and odour. Men may experience redness, itching, swelling, or pain around the penis, along with a strong-odoured discharge. These infections can be quite uncomfortable and may require medical treatment.
Yeast thrives in warm, moist environments, and the extra glucose present in the urine of those taking Jardiance can provide an ideal environment for yeast to grow. This is particularly true for people with diabetes, as high blood sugar levels can also increase the amount of glucose in the urine. The extra glucose in the urine can also attract fungi and bacteria, further increasing the risk of infection.
The symptoms of a genital yeast infection can vary but often include itching, soreness, and pain in the genital area. In some cases, there may also be swelling and redness, indicating inflammation. It is important to seek medical advice if you experience any of these symptoms, as yeast infections can usually be effectively treated with antifungal medications. Left untreated, yeast infections can sometimes lead to more serious complications.
While the occurrence of joint pain as a side effect of Jardiance is unclear, it is always recommended to consult a healthcare provider to ensure the information applies to your personal circumstances.
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Ketoacidosis, a serious side effect, can cause abdominal pain
Jardiance is a medication used to help manage Type 2 diabetes or heart failure. It is generally safe and effective, but like all medications, it can cause side effects. One of the more serious side effects that has been reported is ketoacidosis, a dangerous condition that requires immediate medical attention.
People with ketoacidosis have abnormally high levels of ketones, a type of protein, in their bodies. Typically, the body produces ketones after breaking down fats from your diet. However, Jardiance can cause your body to produce more ketones than usual, leading to a harmful buildup. This excess of ketones can make the blood too acidic, a condition known as ketoacidosis. Ketoacidosis is a serious complication that can be life-threatening and requires immediate medical intervention.
Ketoacidosis can cause a variety of symptoms, including abdominal pain. Other signs and symptoms of ketoacidosis may include nausea, vomiting, dehydration, and low blood pressure. If you experience any of these symptoms while taking Jardiance, it is crucial to seek medical help right away. Do not ignore these warning signs, as delaying treatment can have severe consequences.
It is worth noting that while abdominal pain can be associated with ketoacidosis, it can also be related to other side effects of Jardiance, such as urinary tract infections (UTIs). UTIs are a common side effect of Jardiance and can cause symptoms such as an increased need to urinate, burning during urination, and abdominal pain. Therefore, if you experience abdominal pain while taking Jardiance, it is important to consult your doctor to determine the underlying cause and receive appropriate treatment.
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Jardiance may cause serious allergic reactions, including angioedema
Jardiance is a medication used to treat Type 2 diabetes and heart failure. It is typically taken long-term and can cause both mild and serious side effects. One of the most serious side effects of Jardiance is angioedema, a severe allergic reaction that can be life-threatening and requires immediate medical attention. Angioedema is characterised by large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or genitals. If you experience these symptoms, stop taking Jardiance immediately and seek emergency medical help.
It is important to note that not everyone who takes Jardiance will experience angioedema, and the risk of developing this severe allergic reaction is unknown. However, it is crucial to be aware of this potential side effect and to monitor for any signs or symptoms. If you experience any unusual or concerning symptoms while taking Jardiance, consult your healthcare provider immediately. They can help you manage your symptoms and decide if Jardiance is the best medication for you.
In addition to angioedema, Jardiance may also cause other serious side effects, including ketoacidosis, a serious complication of diabetes that can be life-threatening. Ketoacidosis occurs when there is a buildup of ketones in the body, leading to abnormally high blood acidity. Symptoms of ketoacidosis include nausea, vomiting, abdominal pain, and dehydration, which may lead to low blood pressure and kidney damage. If you experience any symptoms of ketoacidosis, stop taking Jardiance and seek immediate medical attention.
Furthermore, Jardiance has been linked to an increased risk of urinary tract infections (UTIs), vaginal yeast infections in women, and yeast infections of the penis in men. These infections can be bothersome and may require treatment with antibiotics or antifungal medications. If you experience any symptoms of infection, such as discharge, itching, odour, or burning during urination, consult your doctor right away. They can provide guidance and recommend appropriate treatments.
It is always important to carefully consider the potential benefits and risks of any medication before starting treatment. While Jardiance can be effective in managing Type 2 diabetes and heart failure, it is crucial to be aware of its side effects and to monitor your health closely while taking this medication. Regular medical check-ups and blood tests are recommended to ensure that Jardiance is working safely and effectively for you.
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Frequently asked questions
Jardiance (empagliflozin) is a medication used to treat Type 2 diabetes and heart failure.
While muscle pain is not listed as a side effect of Jardiance, some clinical studies have reported joint pain in patients taking the medication. However, a similar number of people taking a placebo in these trials also experienced joint pain, so it is unclear if Jardiance is the direct cause.
Common side effects of Jardiance include urinary tract infections (UTIs), genital yeast infections, increased urination, and nausea.
Yes, Jardiance may cause serious side effects such as perineum infection (Fournier's gangrene), ketoacidosis, low blood sugar, dehydration, and allergic reactions. Some of these side effects can be life-threatening and require immediate medical attention.
It is important to consult your healthcare provider if you experience any side effects while taking Jardiance. They can help determine the best course of action and provide guidance on managing any bothersome symptoms.











































