
Constipation is a common condition that affects people of all ages, and there are many factors that can cause it. Some of the most common causes include a lack of exercise, changes in routine, and not consuming enough fibre and fluids. However, one often overlooked factor is muscle tone, especially in the abdominal wall, diaphragm, and pelvic floor muscles. Low muscle tone can be caused by various factors, including age, injury, and certain medications, and it can significantly impact bowel movements, leading to constipation. This condition, known as anismus or dyssynergic defecation, affects the coordination of muscles and nerves in the pelvic floor, impairing the ability to effectively pass stool. Understanding the role of muscle tone in constipation is crucial for developing effective treatment strategies, such as biofeedback therapy and lifestyle modifications.
| Characteristics | Values |
|---|---|
| Cause | Lack of exercise, aging, ignoring the urge to move bowels, not enough fiber and fluids in the diet, opioid use, laxative use, neurological disorders, metabolic and endocrine disorders, intestinal obstructions, IBS, anismus, nerve damage to the lower spine, spinal cord injury, nerve disease, decreased muscle tone, bladder problems, medications |
| Diagnosis | Digital rectal exam (DRE), sigmoidoscopy, anorectal manometry test |
| Treatment | Biofeedback therapy, enemas, bowel retraining, GCC agonists, chloride channel medications (Linzess, Trulance, Amitiza) |
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What You'll Learn
- Atonic colon, also known as lazy colon, can be caused by laxative addiction
- Neurogenic bowel can be caused by nerve damage to the lower spine
- Pelvic floor dysfunction can cause dyssynergic defecation
- Lack of exercise can lead to constipation
- Opioid-induced constipation is a common side effect of pain medication

Atonic colon, also known as lazy colon, can be caused by laxative addiction
Atonic colon, also known as lazy colon, is a condition where the colon stops responding to signals to evacuate the bowel. This can be caused by laxative addiction, which occurs when a person becomes dependent on laxatives to defecate. Laxatives work by stimulating the bowel muscles with irritants, but when used repeatedly, the muscles build a tolerance, leading to low muscle tone and an atonic colon.
Laxatives are commonly used to treat constipation, but when overused, they can cause the intestinal muscles to weaken and lose their ability to contract and evacuate stool normally. This interference with normal bowel movements can lead to a person becoming addicted to laxatives, requiring higher doses to achieve the desired effect.
Chronic laxative use can cause long-term damage to the digestive system, including the nerves and muscles of the colon. It can also lead to electrolyte disturbances, dehydration, mineral deficiencies, and an increased risk of colon cancer. Therefore, it is important to use laxatives as directed by a healthcare professional and not to abuse them.
The treatment for atonic colon caused by laxative addiction may include enemas or bowel retraining. Non-laxative medications, such as guanylate cyclase-C (GCC) agonists or chloride channel medications, may also be prescribed. Biofeedback therapy can also be effective in training the muscles and improving sensory awareness for bowel movements.
It is important to note that constipation can be caused by various factors, including dietary habits, lack of exercise, medications, neurological disorders, metabolic disorders, intestinal obstructions, and hormonal changes. Therefore, it is always advisable to consult a healthcare provider to determine the underlying cause and receive appropriate treatment.
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Neurogenic bowel can be caused by nerve damage to the lower spine
Low muscle tone can cause constipation. This can be due to a lack of exercise, ageing, or opioid use, among other factors.
Neurogenic bowel, a condition that causes a loss of normal bowel function, can be caused by nerve damage to the lower spine. This nerve damage can be caused by various factors, including:
- Brain or spinal injury
- Health conditions such as multiple sclerosis, Parkinson's disease, or diabetes
- Spina bifida
- Spinal cord lesions or tumours
- Tethered spinal cords
- Accidents, such as motor vehicle collisions or falls
The nerves on the spinal cord that control bowel function are at the S2-S5 level. When these nerves are damaged, it can result in a loss of normal bowel function, including constipation and stool leakage or incontinence. This is because the damage may reduce peristalsis in the muscles around the colon, blocking signals to and from the rectum and anus. As a result, individuals with neurogenic bowel may not feel the urge to have a bowel movement or may be unable to do so even if they want to.
The diagnosis of neurogenic bowel typically involves tests such as an MRI or CT scan of the brain or spinal cord and an ultrasound of the anus. Treatment includes creating a bowel management program with scheduled times to remove stool from the rectum.
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Pelvic floor dysfunction can cause dyssynergic defecation
Low muscle tone can cause constipation. This can be due to a lack of exercise, ageing, or neurological disorders such as Parkinson's disease, spinal cord injury, stroke, or multiple sclerosis. Certain medications, such as opioids, antacids that contain aluminum, and antidepressants, can also cause constipation.
Pelvic floor dysfunction, or pelvic dyssynergia, is a condition that affects the coordination of the muscles and nerves in the pelvic floor, making it difficult to have a bowel movement. This can lead to dyssynergic defecation, or anismus, which is a functional pooping disorder. Dyssynergic defecation is estimated to account for 15-25% of all chronic constipation cases.
People with pelvic floor dysfunction may have difficulty relaxing their pelvic floor muscles during defecation, which can result in hardened stool becoming impacted in the bowels and making it even harder to pass. This condition can affect both men and women and can cause pain and discomfort, negatively impacting one's quality of life. Pregnant women are particularly at risk of developing pelvic floor dysfunction due to the strain on the pelvic floor muscles and tissues during pregnancy and labour.
The most effective treatment for dyssynergic defecation is biofeedback therapy, which uses electrodes on the skin to sense things like muscle tension and brain activity. During a session, a therapist will guide the patient through various muscle-activating and tension-relieving strategies to train the muscles to push and relax effectively for defecation. Relaxation techniques such as warm baths, yoga, and stretching can also help relax the pelvic floor muscles.
If you are experiencing symptoms of pelvic floor dysfunction, it is important to consult a healthcare professional for an official diagnosis and treatment plan.
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Lack of exercise can lead to constipation
Lack of exercise can indeed lead to constipation. The abdominal wall muscles and diaphragm play a crucial role in the process of defecation, and exercise helps maintain good muscle tone, which is important for regular bowel movements. If these muscles are weak, they won't be able to function optimally during defecation.
A sedentary lifestyle or restricted movement due to disability or health issues can cause constipation. However, this doesn't mean that intense workouts are necessary to prevent constipation. Even a 15-minute walk or some light movement throughout the day can help.
The colon responds to activity, and exercise can stimulate intestinal activity. Older individuals, who tend to be less active, may find that increasing their physical activity improves constipation. Additionally, exercise can be a helpful strategy when combined with other constipation-relieving methods, such as increasing fiber and fluid intake.
It is important to note that while exercise is beneficial, it is not a cure-all for constipation. If constipation persists or is accompanied by other symptoms, it is advisable to consult a healthcare professional for guidance and an accurate diagnosis.
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Opioid-induced constipation is a common side effect of pain medication
While low muscle tone can cause constipation, there are many other factors that can lead to constipation. One common cause is the use of opioid pain medication, which can prevent peristalsis and worsen abdominal pain, contributing to bowel obstruction. This is known as opioid-induced constipation (OIC) and is a persistent adverse effect of opioid use. It occurs in about 90% of cancer patients taking opioids and 40% of people taking opioids for chronic non-cancer pain.
OIC is caused by the activation of enteric mu-opioid receptors, which leads to reduced secretions in the gastric, biliary, pancreatic, and intestinal regions, increased water absorption from bowel contents, and decreased gastric motility. This results in harder stools that are more challenging to pass. The condition is challenging to reverse, and even with novel drug combinations, there are no long-term studies on their effectiveness. Therefore, non-opioid pain medications are recommended as the first line of treatment to manage pain and avoid OIC.
If opioids cannot be avoided, it is essential to take proactive measures to prevent constipation. This includes educating patients about the adverse effects of opioids and encouraging lifestyle changes such as a high-fibre diet, ample water intake, and regular exercise. Additionally, the simultaneous use of laxatives and a high-fibre diet may be recommended. Lubiprostone (Amitiza) is a type-2 chloride channel activator that increases fluid secretion in the GI tract, enhancing peristalsis and improving colonic transit time. It is approved for treating OIC in patients with cancer and non-cancer pain. Other approved treatments for OIC include naloxegol, alvimopan, naldemedine, and methylnaltrexone.
It is important to note that OIC can significantly impact a person's quality of life, and an interprofessional approach to patient education and management is crucial. This includes the involvement of a nurse, pharmacist, gastroenterologist, and pain consultant. Pharmacists play a vital role in recommending discontinuing constipating drugs and suggesting alternative options. They should also educate patients about the prevention of constipation when opioids are prescribed. Additionally, biofeedback therapy can help train patients' sensory awareness and muscle activation and relaxation strategies to improve bowel movements.
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Frequently asked questions
Constipation is a common condition where a person experiences infrequent bowel movements or has difficulty passing stools that are often hard and dry.
Constipation can be caused by various factors, including low muscle tone, lack of exercise, changes in routine or diet, certain medications, and neurological or metabolic disorders.
Good muscle tone is important for regular bowel movements. Weak abdominal wall muscles and diaphragm can affect the defecation process. Additionally, low muscle tone in the colon can lead to reduced bowel activity, contributing to a cycle of worsening constipation.
Treatment for low muscle tone-related constipation may include biofeedback therapy, lifestyle changes, and non-laxative medications. Biofeedback uses electrodes to sense muscle tension and guide individuals through muscle-activating and tension-relieving strategies.
Signs that low muscle tone may be contributing to constipation include infrequent bowel movements, difficulty passing stools, and abdominal discomfort. Consulting a healthcare professional is advised for an accurate diagnosis and personalized treatment plan.











































