
Nystatin is an antifungal medication used to treat yeast and fungal infections, particularly those caused by Candida species. It is available in various forms, including oral tablets, capsules, liquids, and topical creams and ointments. While nystatin is generally well-tolerated, it can cause side effects, such as oral irritation, nausea, upset stomach, and diarrhea. In rare cases, nystatin may cause severe allergic reactions and serious skin reactions, such as Stevens-Johnson syndrome, which can lead to flu-like symptoms, including fever and muscle aches. It is important to consult a healthcare professional if any side effects occur, and to seek emergency care for severe reactions.
| Characteristics | Values |
|---|---|
| Can nystatin cause muscle pain? | Yes, in rare cases, oral nystatin may cause Stevens-Johnson syndrome, which can cause flu-like symptoms such as muscle aches. |
| What is nystatin? | An antifungal medication used to treat yeast and fungal infections, especially those caused by Candida species (candidiasis). |
| How is nystatin administered? | Orally (tablet, capsule, liquid, lozenge, suspension), topically (cream, ointment, powder), vaginal tablet. |
| Common side effects | Oral irritation, sensitivity, diarrhoea, nausea, vomiting, stomach pain, gastrointestinal disturbances. |
| Less common side effects | Rash, urticaria, Sevens-Johnson syndrome, generalised pustular eruptions, delayed (type IV) hypersensitivity reactions. |
| Severe side effects | Allergic reactions, serious eye symptoms (blurred vision, tunnel vision, eye pain, etc.), severe nervous system reaction (stiff muscles, high fever, etc.). |
| Precautions | Do not use nystatin if you are allergic to it. Tell your doctor if you are pregnant or breastfeeding. Do not give to a child without medical advice. |
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What You'll Learn
- Oral nystatin may cause Stevens-Johnson syndrome, leading to muscle pain
- Nystatin can cause allergic reactions, which can result in muscle pain
- Side effects of nystatin may include gastrointestinal issues, leading to muscle pain
- Nystatin may cause severe nervous system reactions, resulting in stiff muscles
- Topical nystatin can cause skin discomfort, which may lead to muscle pain

Oral nystatin may cause Stevens-Johnson syndrome, leading to muscle pain
Like all medicines, nystatin can cause side effects, but most people experience none or only minor ones. Oral nystatin is used to treat yeast and fungal infections in the mouth, throat, and intestinal tract. It is not absorbed into the bloodstream and is excreted unchanged in stools.
Oral nystatin may cause Stevens-Johnson syndrome, a rare but severe skin reaction. This condition causes the skin to blister and peel and is often accompanied by flu-like symptoms, including fever and muscle pain. If you experience any of these symptoms, seek emergency medical care as this condition can be dangerous without proper treatment.
Other common side effects of oral nystatin include mouth irritation, nausea, upset stomach, and diarrhea. Some less common side effects include a severe nervous system reaction with stiff muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors, and dizziness. If you experience any severe or bothersome side effects, consult your healthcare provider.
It is important to note that nystatin may also cause serious allergic reactions. Stop taking nystatin and seek immediate medical help if you experience symptoms such as hives, difficulty breathing, or swelling of the face, lips, tongue, or throat. Always follow the directions provided by your healthcare professional and read the medication guides or instruction sheets carefully.
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Nystatin can cause allergic reactions, which can result in muscle pain
Like all medicines, nystatin can cause side effects, but most people experience none or only minor ones. It is an antifungal medication used to treat yeast and fungal infections, specifically those caused by Candida species (candidiasis). Oral nystatin is used to treat mouth and throat (oropharyngeal) and intestinal fungal infections, while topical nystatin is used for skin and vaginal yeast infections.
Other side effects of oral nystatin include mouth irritation, nausea, upset stomach, and diarrhoea. Topical nystatin can cause skin discomfort, such as itching or burning where it is applied. In very rare cases, nystatin can also cause a severe skin rash or allergic reaction. If you experience any of these side effects, stop using the product and consult your pharmacist or doctor.
It is important to note that nystatin may also cause serious nervous system reactions, including very stiff muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors, and dizziness. If you experience any of these symptoms, seek medical advice immediately.
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Side effects of nystatin may include gastrointestinal issues, leading to muscle pain
Nystatin is an antifungal medication used to treat yeast and fungal infections, particularly those caused by Candida species (candidiasis). It is available in various forms, including oral tablets, capsules, liquids, and topical creams and ointments. While nystatin is generally well-tolerated, it may cause side effects in some individuals.
One of the most commonly reported side effects of oral nystatin is gastrointestinal issues, including nausea, vomiting, diarrhoea, and upset stomach. These gastrointestinal side effects can lead to dehydration, which may further contribute to muscle pain and discomfort. Additionally, oral nystatin can cause mouth irritation, oral sensitization, and stomach pain. In some rare cases, oral nystatin may cause a severe skin reaction called Stevens-Johnson syndrome, which can result in flu-like symptoms such as fever and muscle aches.
It is important to note that the side effects of nystatin may vary depending on the individual and the form of administration. While most people may experience no or minor side effects, it is always advisable to consult a healthcare professional if any side effects occur. They can provide guidance and recommend ways to prevent or reduce these side effects.
To minimise the potential gastrointestinal side effects of nystatin, it is recommended to drink plenty of fluids, such as water, to stay hydrated. Additionally, sticking to simple meals and avoiding rich or spicy foods can help reduce stomach-related issues. It is also important to take nystatin liquid after meals or snacks and follow the prescribed dosage instructions.
In summary, while nystatin is generally safe, side effects may include gastrointestinal issues, such as nausea, diarrhoea, and stomach pain, which can indirectly lead to muscle pain due to dehydration. However, the occurrence and severity of side effects can vary, and healthcare professionals can provide guidance on managing them effectively.
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Nystatin may cause severe nervous system reactions, resulting in stiff muscles
Nystatin is an antifungal medication used to treat yeast and fungal infections, specifically those caused by Candida species (candidiasis). It is available in various forms, including oral tablets, liquids, capsules, lozenges, topical creams and ointments, and vaginal tablets. While nystatin is an effective treatment for fungal infections, it can cause side effects in some individuals.
One of the rare but severe side effects associated with nystatin is a nervous system reaction. This reaction can manifest as stiff muscles, along with other symptoms such as a high fever, sweating, confusion, fast or irregular heartbeat, tremors, and feelings of fainting. It is important to seek medical advice if you experience any of these symptoms while taking nystatin.
The occurrence of stiff muscles as a side effect of nystatin is not common, but it can happen. It is essential to be aware of this potential side effect and consult a healthcare professional if you experience muscle stiffness or any other unusual symptoms while taking nystatin. They can advise you on managing the side effects or adjusting your medication if necessary.
In addition to the nervous system reaction, nystatin may also cause other side effects, such as oral and skin irritation, nausea, upset stomach, diarrhoea, and gastrointestinal disturbances. These side effects are typically milder and may not require medical attention. However, if they persist or become bothersome, it is advisable to consult a healthcare professional.
It is worth noting that most people who take nystatin do not experience any side effects or only experience minor ones. However, it is always important to be informed about the potential side effects of any medication and to seek appropriate medical advice if needed.
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Topical nystatin can cause skin discomfort, which may lead to muscle pain
Like all medicines, nystatin can cause side effects, but most people experience none or only minor ones. It is an antifungal medication used to treat yeast and fungal infections (mouth, throat, intestinal, and vaginal infections), particularly those caused by Candida species (candidiasis).
Oral nystatin is used to treat mouth and throat (oropharyngeal) and intestinal fungal infections. It is also available as topical applications for skin and vaginal yeast infections. It is not absorbed into the bloodstream and is only effective for fungal infections on the skin and the mucous lining of the mouth, throat, and gastrointestinal tract.
Topical nystatin can cause skin discomfort, such as burning or itching where it is applied. In very rare cases, it can also cause a severe skin rash or an allergic reaction. Seek emergency care if these occur.
In rare cases, oral nystatin may cause a severe skin reaction called Stevens-Johnson syndrome, which causes the skin to blister and peel. It usually also causes flu-like symptoms, such as a fever and muscle aches. If any of these symptoms appear while taking nystatin, seek emergency care.
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Frequently asked questions
Yes, nystatin can cause muscle pain in rare cases as part of a severe nervous system reaction. This can also include stiffness, high fever, sweating, confusion, fast or uneven heartbeat, tremors, and feeling faint. If you experience any of these symptoms, seek emergency medical help.
Common side effects of nystatin tablets include oral irritation and sensitivity, diarrhoea, nausea, vomiting, stomach pain, and gastrointestinal disturbances.
Yes, in very rare cases, nystatin can cause severe allergic reactions and serious skin reactions such as Stevens-Johnson syndrome. Seek emergency care if you experience any of these symptoms.
If you experience any side effects from nystatin tablets, you should contact your doctor or pharmacist for advice. They may recommend adjusting the dosage or switching to a different medication.
It is recommended to use nystatin only if clearly needed during pregnancy. It is not known if nystatin passes into breast milk, so you should consult your healthcare provider if you are breastfeeding or plan to breastfeed.











































