
Aimovig (erenumab-aooe) is a prescription medicine used to prevent migraines in adults. It is administered via subcutaneous injection, using either an autoinjector pen or a prefilled syringe. While Aimovig is generally well-tolerated, it may cause a range of side effects, from mild to severe. One of the reported side effects is muscle pain, which can be in the form of muscle cramps and spasms. This side effect is typically mild and can be managed by staying hydrated, stretching, or massaging the affected area. However, if muscle pain or any other side effects become bothersome or persistent, it is important to consult a healthcare professional.
| Characteristics | Values |
|---|---|
| Muscle pain | Muscle pain can occur as a result of muscle spasms or cramps, which are possible side effects of Aimovig. |
| Muscle spasms or cramps | Less common side effects of Aimovig, but may be painful or uncomfortable. |
| Treatment for muscle spasms or cramps | Stretching or massaging the affected area, taking hot showers, and drinking plenty of water may help relieve the pain. |
| Other side effects | Injection site reactions (pain, redness, swelling, etc.), constipation, allergic reactions, high blood pressure, Raynaud's phenomenon, etc. |
What You'll Learn

Muscle cramps and spasms
Aimovig (erenumab-aooe) is a medication prescribed to prevent migraine episodes in adults. It is administered as a subcutaneous injection. As with other drugs, Aimovig can cause side effects, some more common than others. These side effects may be temporary, lasting a few days or weeks.
If you are concerned about muscle cramps and spasms while using Aimovig, talk to your doctor. They can suggest ways to help ease your symptoms. Stretching or massaging the affected area may help relieve or lessen this side effect. Hot showers can also be soothing.
To help prevent and ease muscle cramps and spasms, drink plenty of water.
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Injection site pain
Aimovig (erenumab-aooe) is a prescription medicine used for the preventive treatment of migraine in adults. It is administered as a subcutaneous injection using an autoinjector pen or a prefilled syringe.
To prevent and manage injection site pain, you can try the following:
- Apply a cold compress to the injection site immediately after the injection to reduce pain and discomfort.
- Take over-the-counter pain relievers, such as ibuprofen or acetaminophen, to help alleviate pain and inflammation.
- Gently massage the injection site to improve blood flow and reduce muscle tension.
- Use a warm compress or take a hot shower to relax the muscles and improve blood circulation in the affected area.
- Keep the injection site clean and dry, and avoid scratching or rubbing the area to prevent irritation and further discomfort.
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Allergic reactions
Aimovig may cause mild to serious side effects, including allergic reactions. Allergic reactions to Aimovig were not reported in clinical studies, but they have been reported since the medication was approved.
Aimovig may cause serious allergic reactions, including anaphylaxis and angioedema, which can be life-threatening and require immediate medical attention. If you experience any symptoms of an allergic reaction, such as a rash or swelling, call your healthcare provider or get emergency medical help right away. Other possible symptoms of an allergic reaction include swelling of the face, mouth, tongue, or throat, and trouble breathing.
The needle shield within the white or orange cap of the autoinjector and the grey needle cap of the prefilled syringe contain dry natural rubber (a derivative of latex), which may cause allergic reactions in people sensitive to latex. If you have a latex allergy, be sure to inform your doctor before using this medication.
Other Side Effects
In addition to allergic reactions, Aimovig may also cause other side effects, such as constipation, injection site reactions, and muscle cramps or spasms. Severe constipation has been reported in some cases, requiring hospitalization or surgery. Injection site reactions typically include pain, redness, discomfort, and/or swelling around the injection site. These reactions are usually mild and last about a day. Muscle cramps and spasms are less common but may be accompanied by weakness, twitching, and sharp pain in the muscles.
If you experience any side effects that bother you or persist for an extended period, be sure to consult your doctor or pharmacist. They can provide recommendations to alleviate these side effects or suggest alternative treatments.
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High blood pressure
Aimovig (erenumab-aooe) is a prescription medicine used for the preventive treatment of migraine in adults. It is administered as a subcutaneous injection using an autoinjector pen or a prefilled syringe.
The manufacturers of Aimovig warn that high blood pressure may potentially occur, and your risk may be higher if you already have hypertension or other heart problems. If you have a history of these health conditions, it is recommended that you periodically check your blood pressure at home while taking Aimovig. If you experience high blood pressure while using Aimovig, your doctor may suggest switching to an alternative migraine medication or prescribe blood pressure medication.
Aimovig has various other side effects, including allergic reactions, constipation, and muscle spasms or cramps. These are typically mild and temporary, lasting a few days or weeks. However, if side effects persist or become bothersome, it is important to consult a doctor or pharmacist.
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Constipation
Aimovig (erenumab-aooe) is a prescription drug used to treat migraine headaches in adults. It is administered as a subcutaneous injection.
If you experience constipation while taking Aimovig, it is important to contact your doctor or pharmacist. They can suggest ways to help relieve it, such as drinking plenty of water and eating foods high in fibre. However, if the constipation is severe, it is crucial to seek immediate medical advice.
Other common side effects of Aimovig include injection site reactions, such as pain, redness, or swelling, which occur in 3-6% of patients. Muscle cramps and spasms are also reported side effects, and these can often be relieved by staying hydrated.
It is important to note that Aimovig may cause serious side effects, including allergic reactions and high blood pressure. If you experience any concerning symptoms, it is always best to consult your healthcare provider.
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Frequently asked questions
Muscle pain is not a direct side effect of Aimovig. However, muscle cramps and spasms are a reported side effect, which can be a source of muscle pain.
Muscle cramps and spasms are a less common side effect of Aimovig. Injection site reactions, constipation, and mild constipation are more commonly reported.
If you experience any side effects that are ongoing or bothersome, you should talk to your doctor or pharmacist. They may be able to recommend ways to ease this side effect.



