
Amlodipine is a medication used to treat high blood pressure and coronary artery disease. It is also used to relieve chronic stable angina (chest pain). While it is a commonly used medication, it can cause side effects, including muscle pain. Side effects are usually mild and last for a short time, but it is important to be aware of them and consult a doctor if they persist or become bothersome.
| Characteristics | Values |
|---|---|
| Muscle pain | Rare side effect; a 52-year-old woman with asthma and hypertension reported severe, generalized muscle and joint pain |
| Muscle tremors | Some people have reported experiencing muscle tremors (shakiness) |
| Stiff muscles | Some people have reported experiencing stiff muscles |
| Abnormal muscle movements | Some people have reported abnormal muscle movements |
| Muscle weakness | A 52-year-old woman with asthma and hypertension reported muscle weakness |
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What You'll Learn

Amlodipine can cause muscle pain and stiffness
Amlodipine is a medicine used to treat high blood pressure and coronary artery disease. It is a type of calcium channel blocker that helps manage blood pressure by relaxing and widening the blood vessels, which reduces the amount of work the heart has to do.
Like all medicines, amlodipine can cause side effects, although not everyone experiences them. These side effects are usually mild and tend to disappear as your body gets used to the medicine. However, amlodipine has been associated with muscle pain and stiffness in some cases.
A case study published in PubMed reported a 52-year-old woman experiencing severe, generalized muscle and joint pain, muscle stiffness, and weakness after two months of amlodipine therapy for hypertension. Her symptoms persisted even after the dosage was increased, and she experienced a sudden onset of left-sided facial numbness and a severe headache.
In rare cases, amlodipine can cause muscle tremors and abnormal muscle movements. If you experience shaky or stiff muscles, or any other movement changes, it is important to inform your doctor or prescriber right away. They may advise you to stop taking amlodipine or adjust your dosage.
Other common side effects of amlodipine include dizziness, lightheadedness, fainting, headaches, nausea, vomiting, chest pain, and shortness of breath. If you experience any bothersome or persistent side effects, be sure to consult your healthcare provider for advice and guidance.
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It can also cause muscle weakness
Amlodipine is a medicine used to treat chronic stable angina (chest pain) and vasospastic angina. It is also used to lower the risk of hospitalisation due to chest pain, heart failure, heart attack, stroke, or death in some patients.
Like all medicines, amlodipine can cause side effects, but not everyone experiences them. The most commonly reported side effects include headaches, edema, rash, fatigue, and dizziness.
Amlodipine can also cause muscle pain, tenderness, and weakness. In rare cases, it can lead to severe neuromuscular complications, including myopathy, myalgias, arthralgias, and weakness. For instance, a case study published in PubMed reported that a 52-year-old woman experienced severe, generalized muscle and joint pain, muscle stiffness, and weakness after two months of amlodipine therapy.
The risk of muscle-related side effects may be higher if you have low thyroid function or kidney problems, are 65 or older, or are taking certain other medications. If you experience abnormal muscle pain, tenderness, or weakness (with or without a fever), contact your doctor immediately. They may recommend adjusting your dosage or switching to a different medication.
It is important to note that serious side effects from amlodipine are rare, occurring in less than 1 in 10,000 people. However, if you experience any side effects that bother you or last for more than a few days, it is recommended to consult your doctor or pharmacist for advice.
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It can cause muscle tremors
Amlodipine besylate is a medicine used to treat high blood pressure and coronary artery disease. It is a type of calcium channel blocker that helps manage blood pressure by relaxing and widening the blood vessels.
Like all medicines, amlodipine can cause side effects, although not everyone experiences them. These side effects are usually mild and tend to disappear as your body gets used to the medicine. However, in rare cases, amlodipine can cause muscle tremors.
Muscle tremors are involuntary, rhythmic muscle contractions that can cause shakiness in the affected muscles. If you experience muscle tremors after taking amlodipine, it is important to inform your doctor or prescriber immediately. They may advise you to stop taking the medication.
In addition to muscle tremors, amlodipine has been associated with other muscle-related side effects. These include muscle stiffness, weakness, and pain. In some cases, patients have reported severe, generalized muscle and joint pain after taking amlodipine. If you experience any unusual or persistent muscle symptoms while taking amlodipine, it is important to seek medical advice.
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It can cause dizziness
Amlodipine is a medicine used to treat high blood pressure and coronary artery disease. It is also used to relieve chronic stable angina (chest pain). While it can be effective, it may cause some unwanted side effects.
Dizziness is one of the most common side effects of amlodipine. It can cause lightheadedness and fainting, especially when getting up suddenly from a lying or sitting position. This is due to a sudden drop in blood pressure. If you experience dizziness, it is important to stop what you are doing and sit or lie down until you feel better. It is advised not to drive, ride a bike, or operate tools or machinery until the dizziness passes.
The risk of dizziness may be increased by certain factors, such as exercising or being in hot weather, as heavy sweating can lead to dehydration and further reduce blood pressure. Alcohol consumption can also increase the risk of dizziness and other side effects. Therefore, it is recommended to reduce caffeine and alcohol intake while taking amlodipine.
In addition to dizziness, amlodipine may cause other side effects, including headache, fatigue, nausea, and muscle tremors. In rare cases, it can lead to severe muscle pain, stiffness, and weakness, as reported by a 52-year-old woman who was undergoing amlodipine therapy for hypertension. However, these side effects are typically mild and temporary, often improving as the body adjusts to the medication.
It is important to be aware of the potential side effects of amlodipine and to consult a doctor or pharmacist if they become bothersome or persist for an extended period. Adjustments to the dosage or alternative medications may be considered if the side effects significantly impact an individual's well-being.
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It can cause chest pain
Amlodipine is a medicine used to treat high blood pressure and coronary artery disease. It is also used to relieve chronic stable angina (chest pain) or vasospastic angina (Prinzmetal's or variant angina). It is a calcium channel blocker that works by relaxing the blood vessels, which helps decrease the amount of work the heart has to do.
Like all medicines, amlodipine can cause side effects, although not everyone gets them. These side effects are usually mild and may improve as your body gets used to the medicine. However, chest pain is a possible sign of a heart attack and needs to be checked out as soon as possible. Do not drive yourself to the emergency room, and call an ambulance if you experience chest pain.
Amlodipine may cause worsening of angina (chest pain) or a heart attack in certain patients with severe heart or blood vessel disease. Check with your doctor right away if you are experiencing chest pain or discomfort, a fast or irregular heartbeat, nausea, vomiting, pain or discomfort in the arms, jaw, back, or neck, trouble breathing, or sweating.
In rare cases, amlodipine can cause severe neuromuscular complications, including myopathy, myalgias, arthralgias, and weakness. A 52-year-old woman with asthma and newly diagnosed hypertension reported severe, generalized muscle and joint pain, muscle stiffness, and weakness after two months of amlodipine therapy.
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Frequently asked questions
Yes, amlodipine has been associated with severe neuromuscular complications, including myopathy, myalgias, arthralgias, and weakness. In one case, a 52-year-old woman reported severe, generalized muscle and joint pain, muscle stiffness, and weakness while taking amlodipine.
If you experience muscle pain or any other side effects that are bothersome or do not go away, you should contact your doctor or pharmacist for advice.
Some other common side effects of amlodipine include headache, dizziness, fatigue, nausea, and chest pain. Serious side effects are rare but may include allergic reactions, heart attack, and low blood pressure.








