
The SARS-CoV-2 virus, which causes COVID-19, has been linked to a wide range of symptoms, including muscle and joint pain, fatigue, and weakness. These symptoms can persist for months after the initial infection and are commonly associated with long COVID. Research suggests that COVID-19 can lead to muscle deterioration, especially in patients requiring hospitalization and intensive care. Treatment methods, such as the use of steroids, paralytic agents, and nerve blocks, can also accelerate muscle breakdown. Recovery from COVID-19 often involves restoring muscle mass and strength, improving physical endurance, and managing ongoing symptoms.
| Characteristics | Values |
|---|---|
| Muscle deterioration | Can be caused by steroids, paralytic agents, and nerve blocks used in COVID-19 treatment |
| Muscle pain | Can be treated with medication, physical therapy, aquatic therapy, or a hot bath |
| Muscle strength | Can be restored with breathing exercises |
| Impact on daily life | Fatigue and reduced energy levels can limit normal daily activities |
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Muscle and joint pain
The causes of muscle and joint pain after COVID-19 are still being studied. However, some scientists believe that the virus may cause joint and muscle inflammation. Others believe that the body's immune response to the virus may be to blame. Inactivity due to necessary rest during the infection can also cause muscles and joints to become stiff and sore.
If you experience muscle and joint pain after COVID-19, it is important to consult a doctor, especially if the pain is persistent or severe. Doctors will typically refer patients to physical therapy, and in some cases, to behavioral and mental health services due to the psychological impact of their COVID-19 experience.
To ease the pain, a hot bath can be beneficial. It is important to ensure that the water temperature is not too hot and to be careful when getting out of the tub to avoid slipping or falling.
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Long-term effects
While most patients with COVID-19 recover fully, about 6 in 100 people who contract the virus develop post-COVID-19 conditions with medium- to long-term effects. The risk of long-term disability has not disappeared, even five years after the pandemic began.
The long-term effects of COVID-19 on the body can vary. Some people experience chronic fatigue, brain fog, and other symptoms that limit their ability to perform daily activities. Others may develop more serious conditions such as lung and heart damage or microbiome changes in the gut. In addition, COVID-19 can speed up muscle breakdown and weakness, including the deterioration of respiratory muscles that control inhalation and exhalation. This can be caused by the use of steroids, paralytic agents, and nerve blocks in patients requiring ventilators. Hospitalization and bed rest can also contribute to the loss of muscle strength and mass.
Restoring muscle mass and strength, physical endurance, breathing capacity, mental clarity, emotional well-being, and daily energy levels are important for recovery from COVID-19. Individual recovery needs vary depending on the patient and their COVID-19 course. For example, people with post-exertional malaise may experience disproportionate tiredness after a little too much activity.
The neurocognitive effects of long COVID are also numerous and troubling, with 18 to 36 percent of patients experiencing neurocognitive symptoms. A 2023 brain imaging study of unvaccinated people who recovered from mild to moderate coronavirus infections found evidence of prolonged neuroinflammation and alterations to white matter. Researchers have also found brain atrophy in areas related to memory and emotion regulation among patients with even mild cases of COVID-19. Some studies suggest that COVID-19 may increase the risk of developing dementia or cognitive impairment in adults.
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Hospitalization
Studies have found that patients hospitalized with COVID-19 experienced significant muscle weakness compared to those who were not hospitalized. This weakness can persist for up to three months after discharge, severely limiting activities such as walking, climbing stairs, and standing for extended periods. Preventing muscle weakness in hospitalized patients is crucial, especially considering the median hospital stay of over seven days. Early mobilization and physical exercise are necessary to prevent and address muscle deterioration, even during the acute phase of COVID-19 infection.
Close to discharge from COVID-19 hospitalization, more than 50% of patients exhibited peripheral and respiratory muscle weakness. This muscle weakness was associated with advanced age, hypertension, and low weight. Patients with peripheral weakness often required more physiotherapy and had more oncological diseases, while respiratory weakness was more prevalent in men. These findings highlight the importance of preventive measures and post-hospitalization rehabilitation programs, including physiotherapy, to aid in muscle strength recovery.
In addition to physical therapy, patients recovering from COVID-19, especially those hospitalized for extended periods, may benefit from behavioral and mental health services. The psychological impact of a prolonged hospital stay can lead to symptoms such as depression, anxiety, stress, and fear, which can amplify the perception of physical pain. Exercise is recommended as an effective form of treatment for muscle and joint conditions, and a physical therapist can develop an individualized exercise regimen that considers the patient's limitations. In some cases, aquatic therapy may be suggested for its benefits, including greater pain-free movement, relaxed muscles, increased strength, and improved endurance.
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Recovery
Pulmonary rehabilitation programs and early mobilization have proven to be highly beneficial during the acute phase and post-illness recovery process. These programs help patients improve their breathing, increase physical endurance, overcome psychological disorders, and enhance their overall quality of life.
Breathing exercises are an essential part of the recovery process. Deep breathing exercises help restore lung function by engaging the diaphragm and promoting relaxation in the nervous system. Patients are advised to practice deep breathing while lying on their back and stomach.
The recovery process should be tailored to each individual's needs, considering their unique circumstances and the severity of their COVID-19 infection. Hospitalization, intensive care, and prolonged bed rest can contribute to muscle deterioration and loss of muscle strength. Therefore, it is crucial to gradually reintroduce movement and physical activity to rebuild muscle mass and improve strength and mobility.
Additionally, COVID-19 can lead to acute sarcopenia, a condition characterized by rapid muscle loss and functional deterioration. This complication can significantly impact a patient's prognosis and ability to perform daily tasks. Addressing acute sarcopenia through targeted rehabilitation programs is crucial for post-COVID-19 recovery.
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Treatment
While the exact mechanisms by which COVID-19 affects muscles are not yet fully understood, there are several treatment options available to address muscle deterioration caused by the virus. Here are some key aspects of treating muscle deterioration associated with COVID-19:
- Pulmonary Rehabilitation and Early Mobilization: Pulmonary rehabilitation programs have proven highly beneficial during the acute phase and post-illness recovery. These programs help patients improve their breathing, increase physical capacity, overcome psychological disorders, and enhance their overall quality of life. Early mobilization is crucial to counteracting the negative effects of prolonged bed rest, which can lead to a decrease in muscle mass and strength.
- Addressing Inflammatory Responses: COVID-19 triggers inflammatory responses, such as cytokine storms, that contribute to muscle deterioration. Treating severe inflammation and managing the cytokine storm during the early stages of the disease can help mitigate its impact on muscles.
- Breathing Exercises: Deep breathing exercises are an essential part of recovery. They help restore lung function by engaging the diaphragm and promoting a relaxation response in the nervous system. This, in turn, can positively impact overall respiratory muscle function.
- Individualized Physical Therapy: Many patients experience post-COVID-19 fatigue and reduced physical endurance. Physical therapy can be tailored to each patient's needs, gradually helping them restore muscle strength, endurance, and daily energy levels.
- Nutrition and Caloric Intake: Adequate caloric intake during the recovery process is vital. Ensuring sufficient energy intake can help counteract muscle loss and support the body's recovery process.
- Mental Health Support: The pandemic has negatively impacted people's mental health, and COVID-19 itself can contribute to anxiety, depression, and insomnia. Addressing these mental health challenges is crucial for overall recovery, including physical well-being.
- Research-Informed Treatment Plans: As research progresses, healthcare professionals can develop more targeted treatment plans for patients with COVID-19-related muscle impairment. Further understanding of the correlation between COVID-19 and skeletal muscle damage will enable more effective treatments.
It is important to remember that recovery from COVID-19 can be a gradual process, and individual recovery needs can vary. A holistic approach that considers physical, mental, and emotional well-being is essential for treating muscle deterioration and other long-term effects of COVID-19.
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Frequently asked questions
Hospitalization and virus infection can erode muscle strength and mass. Bed rest can cause immobility, which can be reversed through physical therapy.
COVID-19 can cause muscle and joint pain, which is typically associated with long COVID. This pain can be very widespread and can be experienced in multiple areas or be isolated to a single area.
Global estimates indicate that 6 in 100 people with COVID-19 develop post-COVID-19 condition. However, recent research shows that the chances of developing it have reduced.
Common symptoms include fatigue, breathlessness, muscle or joint pain, impaired sleep, depression, anxiety, dizziness, and light-headedness.
Restoring muscle mass and strength is important for former hospital patients and COVID long-haulers. Breathing exercises are a standard part of recovery, as well as physical therapy and aquatic therapy.










































