
Paralysis is the loss of muscle function in part of the body. It occurs when nerve signals to the muscles are disrupted, which can be caused by strokes, spinal cord injuries, nerve disorders, or nerve diseases. Paralysis can be complete or partial, temporary or permanent, and can affect one or both sides of the body. It can also be localised to one area, such as the face, hands, feet, or vocal cords, or it can be widespread.
| Characteristics | Values |
|---|---|
| Definition | Loss of muscle function in part of the body |
| Cause | Disruption of nerve signals to muscles |
| Common causes | Strokes, spinal cord injuries, nerve disorders |
| Types | Paraplegia, quadriplegia, partial paralysis, complete paralysis, temporary paralysis, permanent paralysis, localised paralysis |
| Nerve disorders | Multiple sclerosis, Bell's palsy, demyelinating diseases, motor neuron diseases |
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What You'll Learn

Strokes
Paralysis is a common disability resulting from a stroke, affecting 90% of people who have had a stroke in one form or another. It occurs when the brain loses the ability to send messages to the muscles, causing a disruption in the transmission of neural impulses between the brain and the muscles. This can be caused by damage to the brain, which can affect the body's ability to move and coordinate, leading to problems with posture, walking and balance. Paralysis usually affects one side of the body, opposite the side of the brain damaged by the stroke. It may affect the face, arm, leg or the entire side of the body. Some patients also experience dysphagia, or difficulty swallowing, due to damage to the part of the brain that controls the muscles for swallowing.
Physiotherapy is essential for treating stroke paralysis. Regular sessions can help restore mobility by enhancing muscle tone and encouraging movement. Tailored exercises can strengthen muscles and play a critical role in the recovery process.
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Spinal cord injuries
Paralysis is the loss of muscle function in part of your body. It occurs when something disrupts nerve signals to your muscles, preventing you from making voluntary movements. It can be complete or partial, and it can occur on one or both sides of your body, or in just one area. Paralysis of the lower half of your body, including both legs, is called paraplegia, while paralysis of the arms and legs is quadriplegia. Most paralysis is due to strokes or injuries, such as spinal cord injuries or a broken neck.
The effects of spinal cord injuries can vary depending on the individual and the specific location and severity of the injury. In addition to paralysis, other possible effects include loss of sensation, difficulty breathing, impaired bladder and bowel control, and pain or numbness. It is important to seek immediate medical attention for spinal cord injuries, as prompt treatment can help minimise the long-term impact and improve the chances of recovery.
Treatment for spinal cord injuries typically involves a combination of medical interventions and rehabilitation. Medical interventions may include surgery to stabilise the spine and reduce further damage, as well as medications to reduce inflammation and promote healing. Rehabilitation involves a team of specialists, including physical therapists, occupational therapists, and psychologists, who work with the individual to regain function and adapt to any lasting effects of the injury.
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Nerve disorders
Paralysis occurs when something disrupts nerve signals to your muscles, resulting in an inability to make voluntary movements. This can be caused by nerve disorders such as multiple sclerosis, a demyelinating disease where the protective coating around nerve cells, called the myelin sheath, is damaged over time. This damage weakens the muscles and makes it harder for neurons to send signals throughout the body, eventually leading to paralysis.
Motor neuron diseases (MNDs) are another type of nerve disorder that can cause paralysis. Motor neurons are the nerve cells that control the muscles used for walking, breathing, speaking, and moving limbs. There are two types of motor neurons: upper motor neurons, which send signals from the brain to the spinal cord; and lower motor neurons, which receive these signals and transmit them to the muscles. When something interferes with these nerve signals, paralysis can occur.
Bell's palsy is another nerve disorder that causes temporary facial paralysis. Paraplegia, which involves paralysis of both legs, and quadriplegia, affecting all four limbs, are other types of paralysis that can result from nerve disorders.
Periodic paralysis is a rare condition that causes sudden and repeated attacks of muscle weakness, stiffness, or paralysis. The symptoms subside between attacks, and the paralysis can be either partial or complete. Localized paralysis affects a specific area, such as the face, hands, feet, or vocal cords.
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Demyelinating diseases
Paralysis is the loss of muscle function in part of your body. It occurs when something disrupts nerve signals to your muscles, making it impossible to make voluntary movements. This can be complete or partial, and it can occur on one or both sides of the body. It can also be localised to one area, or it can be widespread.
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Motor neuron diseases
Paralysis is the loss of muscle function in part of the body. It occurs when nerve signals to the muscles are disrupted, which can be caused by strokes, spinal cord injuries, nerve disorders, or demyelinating diseases. One such demyelinating disease is multiple sclerosis, which damages the myelin sheath, the protective coating around nerve cells, making it harder for neurons to send signals throughout the body.
ALS is the most common form of MND, affecting both upper and lower motor neurons. It causes a gradual loss of control over the muscles that help with walking, talking, chewing, swallowing, and breathing. Over time, these muscles weaken and waste away, leading to stiffness and twitches. While most cases of ALS are sporadic, about 5-10% of cases in the US are familial.
Other types of MNDs include primary lateral sclerosis (PLS), progressive muscular atrophy (PMA), progressive bulbar palsy, pseudobulbar palsy, and monomelic amyotrophy (MMA). These diseases can be classified by which part of the motor neurons are affected, which parts of the body are first affected, whether they are genetic, and the age at which they start.
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Frequently asked questions
Paralysis is the loss of muscle function in part of your body. It happens when something goes wrong with the way messages pass between your brain and muscles.
Paralysis can be caused by strokes, spinal cord injuries, nerve disorders, nerve diseases, autoimmune diseases, and demyelinating diseases.
Paralysis can be complete or partial. It can occur on one or both sides of your body. It can also be localized to one area or widespread. There is also a rare condition called periodic paralysis that causes sudden repeated attacks of muscle weakness, stiffness, or paralysis.







































