
Human skeletal muscle is composed of cells known as myocytes, or muscle fibres. These fibres can be classified based on two main criteria: the speed of contraction and how they regenerate adenosine triphosphate (ATP), which provides the energy for muscle contraction. Based on these criteria, there are three main types of muscle fibres: slow oxidative (SO), fast oxidative (FO), and fast glycolytic (FG). Slow-twitch muscle fibres are more abundant in endurance athletes, while fast-twitch fibres are more common in power athletes. The distribution of these fibres can be influenced by training, with strength and power training favouring fast-twitch fibres and endurance training favouring slow-twitch fibres.
| Characteristics | Values |
|---|---|
| Type | IIa (FO) or intermediate fibers |
| Contraction Speed | Fast |
| Contraction Power | Higher tension |
| Resistance to Fatigue | Resistant to fatigue |
| Contraction Duration | Prolonged |
| Myoglobin Content | Low |
| Capillary Density | Low |
| Mitochondria Density | Similar to Type I |
| Glycosomes | Moderate |
| Anaerobic Metabolism | Capable |
| Colour | Lighter pink |
| Training | Power training at faster speeds |
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What You'll Learn

Slow-twitch vs fast-twitch muscle fibres
Slow-twitch and fast-twitch muscle fibres are subtypes of skeletal muscle fibres, distinguished by their metabolism and function. Most muscles contain a combination of both types, but the proportion of each varies significantly between individuals.
Slow-twitch muscle fibres, also known as Type 1 or Type SO (Slow Oxidative) fibres, are designed for endurance activities that require long-term, repeated contractions. They are involved in many daily activities, such as walking, jogging, and other light to moderate-intensity activities. These fibres rely on aerobic respiration, using oxygen and blood to produce energy and power muscle contractions. Due to their high oxygen requirements, they are associated with a large number of blood vessels, giving them a reddish colour. They contract relatively slowly and are not suited for powerful, rapid movements. However, they do not fatigue quickly and can maintain prolonged activity without tiring.
On the other hand, fast-twitch muscle fibres, also known as Type 2 or Type FG (Fast Glycolytic) fibres, are responsible for rapid, powerful movements of short duration. They are used for high-intensity activities such as sprinting, jumping, and powerlifting. Unlike slow-twitch fibres, fast-twitch fibres rely on anaerobic respiration, utilising carbohydrates stored in the muscles to produce energy quickly. This allows them to generate a large amount of force but also leads to faster fatigue. Fast-twitch fibres have fewer blood vessels and a paler colour due to reduced oxygen requirements. They contract at a faster rate than slow-twitch fibres, making them ideal for activities requiring speed and power.
The proportion of slow-twitch to fast-twitch muscle fibres is influenced by genetics, age, and physical activity. Individuals who excel at endurance sports tend to have a higher percentage of slow-twitch fibres, while those who perform better at sprinting events typically possess more fast-twitch muscle fibres. Age also plays a role, as muscle mass generally peaks around 30 years of age and then begins to decline in the late 30s or early 40s unless active measures are taken to counteract this loss. Additionally, training and physical activity can impact the composition and performance of muscle fibres. For example, endurance training can increase the endurance level of fast-twitch fibres, while sprint training can enhance the power generated by slow-twitch fibres.
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How muscle fibres are classified
Skeletal muscle is the most common type of muscle in the body, comprising 30% to 40% of total body mass. They are part of the voluntary muscular system and are attached to bones by tendons, allowing for a wide range of movements. Each muscle contains multiple fascicles, or bundles of muscle fibres, and each fibre and muscle is surrounded by connective tissue.
Skeletal muscle fibres are classified into two main types: type 1 and type 2. Type 1 muscle fibres, also known as slow-twitch fibres, contract relatively slowly and use aerobic respiration (oxygen and glucose) to produce ATP. They have a higher density of mitochondria, giving them a darker appearance. Type 2 fibres, or fast-twitch fibres, are further divided into subtypes: type 2A, type 2X, and type 2B. Type 2 fibres contract faster and are used for quick, powerful movements, but they fatigue more quickly. Type 2A fibres can also use oxygen to generate energy, but they contain fewer mitochondria, making them lighter in colour. Type 2B fibres do not use oxygen and instead rely on stored energy for short bursts of movement, resulting in an even lower number of mitochondria and a whiter appearance.
In addition to these classifications, muscle fibres can also be categorised based on their colour, which reflects their myoglobin content. Type 1 fibres are red due to high levels of myoglobin, while type 2 fibres are white due to relatively low levels. Furthermore, muscle fibres can be classified based on their ATP regeneration mechanisms, which include creatine phosphate, anaerobic glycolysis, and aerobic metabolism.
The classification of muscle fibres is important in understanding their susceptibility to various diseases and disorders. For example, certain muscle disorders exhibit specific patterns of fibre-type degeneration, and changes in fibre type proportions have been observed in patients with chronic heart failure and chronic obstructive pulmonary disease (COPD).
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Training to improve fast-twitch muscle fibres
Fast-twitch muscle fibres are essential for athletes who require speed and power, such as sprinters and weightlifters. They are also useful for everyday activities such as quickly lifting a box or jumping out of the way of a bicycle or car.
To improve your fast-twitch muscle fibres, you should focus on high-intensity, explosive exercises that recruit these fibres. Here are some specific training methods to improve your fast-twitch muscle fibres:
Plyometric exercises
Plyometric exercises are explosive movements that involve jumping and landing, such as box jumps, jump squats, and burpees. These exercises are great for developing fast-twitch muscle fibres because they require a lot of power and force.
Sprint intervals
Sprinting is one of the best ways to improve your fast-twitch muscle fibres. Sprint intervals involve short bursts of all-out effort followed by periods of rest. This type of training can help you build speed and power and improve your cardiovascular fitness.
Olympic lifts
Olympic lifts are complex movements that require skill and technique. They are also great for developing fast-twitch muscle fibres. Examples include power cleans, snatches, and push presses.
Isometric exercises
Isometric exercises involve holding a static position for an extended period, focusing on muscle contraction. Examples include wall sits, planks, and static lunges. These exercises can help develop fast-twitch muscle fibres by increasing muscle endurance.
Stationary cycling
Set the resistance on a stationary bicycle or similar pedalling machine to a comfortable level. Pedal as fast as you can for 30 seconds, then take a 20-minute break. Repeat this cycle 2-3 times in a single workout session.
Weight training
Lifting weights is one of the best ways to build and maintain fast-twitch muscle fibres. Aim for a moderate intensity with a heavier weight—lift until your muscles reach fatigue with a moderate amount of weight. For example, lift a weight that you can squat for about 10 to 15 reps at a time.
It's important to note that rest and recovery are crucial. Avoid overtraining, as it can lead to injuries. Aim to perform these exercises at least twice a week, as muscle gains start to diminish after four days of inactivity.
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The role of AMPK in fast-twitch muscle fibres
Fast-twitch muscle fibres, also known as type II or fast-glycolytic (FG) fibres, are one of the three main types of muscle fibres, the others being slow-twitch (type I) and intermediate (type IIa) fibres. Fast-twitch fibres are capable of producing rapid, powerful movements but fatigue quickly, while slow-twitch fibres possess slower twitch speeds and are relatively fatigue-resistant.
AMP-activated protein kinase (AMPK) is a regulator of energy homeostasis during exercise. It is a heterotrimeric enzyme that senses the energy state of various cell types, including muscle cells. AMPK has been shown to play a role in the age-related atrophy and decreased growth capacity of fast-twitch muscle fibres. Aged skeletal muscle displays higher AMP and lower PCr concentrations at rest and after exercise, which activate AMPK. Chronic AMPK activation in resting muscle leads to basal fibre atrophy and death.
In addition, AMPK may play a role in fibre type-shifting in response to exercise training. High-intensity resistance training and endurance training can both increase AMPK activation. Inhibition of AMPK activity has been shown to blunt the fast-to-slow fibre type transition in rodents.
Furthermore, AMPK activation is influenced by muscle fibre type and exercise intensity. High-intensity exercise activates AMPK predominantly in fast-twitch glycolytic fibres (type II). However, the regulation of AMPK during exercise may also depend on other factors such as denervation, fitness level, sex, and age.
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Fast-twitch muscle fibres in elite athletes
Fast-twitch muscle fibres, also called white fibres or type II fibres, are skeletal muscles that help with power performance for short periods. They are optimised for short, intense activities, such as sprinting and jumping, and are the body's first choice for muscle use before tapping into slow-twitch muscles. Fast-twitch muscles are anaerobic, using sources of energy already present in the body, such as glucose, to make adenosine triphosphate (ATP).
Type II muscle fibres can be further broken down into two types: type IIa and type IIx (formerly known as type IIb). Type IIa fibres are also known as intermediate muscle fibres and can be used for longer periods as they fatigue more slowly than type IIx fibres. Type IIx fibres are better at providing force but fatigue faster, making them inefficient.
In terms of elite athletes, studies have shown that athletes in strength or power sports, such as weightlifting, tend to have a higher proportion of fast-twitch muscle fibres. This is particularly true for heavyweights, who possess atypically high quantities of type IIa/IIx fibres. The extreme fast-twitch abundance in these athletes helps explain how they are able to generate high forces in short time frames.
Genetics also play a role in athletic performance, with some individuals being genetically more likely to have more type II muscle fibres. The ACTN3 and ACE genes, for example, have been linked to strength and endurance and influence the fibre type that makes up muscles. However, it is difficult to know one's exact proportion of muscle fibres, as this can only be measured through a muscle biopsy.
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Frequently asked questions
Fast-twitch muscle fibres, also known as Type II or Type IIa/IIx fibres, are muscle cells that facilitate short, powerful movements. They contract quickly and produce high tension.
Slow-twitch fibres, or Type I fibres, contract slowly and are used for endurance activities like long-distance running or cycling. Fast-twitch fibres, on the other hand, are used for explosive movements and generate more power.
Exercises that stimulate fast-twitch muscle fibres include heavy barbell squats, heavy barbell bench presses, medicine ball slams, chest passes, and box jumps.
Yes, strength and power training can shift the muscle fibre distribution in favour of fast-twitch fibres. Training with heavier loads (over 70% of 1RM) or using lighter weights with explosive tempos are effective ways to activate and train these fibres.











































