
Ouch—esophageal muscle spasms can be painful. They occur when the muscular tube that connects your mouth to your stomach (the esophagus) tightens or contracts abnormally. When this happens, food and liquids can get stuck in your esophagus, causing regurgitation or a feeling of heartburn. Esophageal spasms can be tricky to diagnose since several conditions cause similar symptoms, such as chest pain and trouble swallowing. While the exact cause of esophageal spasms is unknown, they may be connected to a malfunction of the nerves that control the muscles within the esophagus, and certain foods and drinks, stress, and acid reflux (GERD) can trigger them.
| Characteristics | Values |
|---|---|
| Definition | Abnormal contractions in the muscular tube that connects the mouth to the stomach |
| Types | Diffuse esophageal spasms, Nutcracker esophagus (or jackhammer esophagus), Hypercontractile esophagus |
| Symptoms | Pain, difficulty swallowing, regurgitation, chest pain, heartburn |
| Causes | Faulty nerve signals, GERD, anxiety or stress, certain foods and drinks, certain medications |
| Treatment | Peppermint oil, medication, botulinum injections, myotomy surgery, home remedies, lifestyle changes |
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What You'll Learn

Faulty nerves controlling the oesophagus muscles
Although the exact cause of oesophageal spasms is unknown, some experts believe that they are caused by faulty nerves that control how the oesophagus muscles work. These faulty nerves may be related to excess acid in the oesophagus, which can be caused by gastroesophageal reflux disease (GERD). GERD is a condition where stomach acid flows back up into the oesophagus, possibly damaging the nerves. People with oesophageal spasms often also have chronic acid reflux.
Recent research suggests that long-term opioid use may also be a contributing factor. Those who use opioids for three months or longer are more likely to develop oesophageal spasms. However, more research is needed to confirm this and identify other potential risk factors.
Oesophageal spasms can cause minor to severe symptoms, including chest pain and difficulty swallowing. The spasms are caused by abnormal muscle contractions in the oesophagus, which make it harder for food and liquids to reach the stomach. In some cases, the food or liquid may come back up the oesophagus, a process known as regurgitation.
There are two main types of oesophageal spasms: distal (or diffuse) oesophageal spasms and hypercontractile (nutcracker or jackhammer) oesophagus. Distal oesophageal spasms are characterised by uncoordinated muscle contractions, mainly in the lower part of the oesophagus, which can lead to regurgitation. On the other hand, hypercontractile oesophagus involves excessively strong muscle contractions that can cause severe pain, especially when swallowing.
Treatment options for oesophageal spasms include medication, such as calcium channel blockers and nitrates, and therapies like botulinum toxin (Botox) injections, which temporarily paralyse the oesophagus muscles to stop spasms. Tricyclic antidepressants can also target the faulty nerves in the oesophagus, providing pain relief. In more severe cases, surgery, such as a myotomy or POEM (a minimally invasive procedure), may be recommended if other treatments have been unsuccessful.
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Acid reflux (GERD)
Acid reflux, also known as gastroesophageal reflux disease (GERD), is a commonly diagnosed chronic condition that occurs when stomach contents flow back up into the oesophagus. This backflow of stomach acid can damage the nerves in the oesophagus, leading to esophageal spasms. Esophageal spasms are abnormal muscle contractions in the oesophagus that disrupt the normal passage of food and liquids to the stomach. While the exact cause of esophageal spasms remains unknown, there is a potential link between acid reflux and these spasms.
People with acid reflux often experience symptoms such as chest pain, a sore throat, bad breath, and nausea. In some cases, acid reflux can trigger asthma-like symptoms, and vice versa. The aspiration of stomach acid into the airways caused by acid reflux can lead to breathing difficulties. Additionally, if an individual already has asthma, the pressure changes during an asthma attack can aggravate acid reflux. Therefore, effectively managing one of these conditions can help alleviate the other.
The treatment for acid reflux often begins with lifestyle changes, including dietary modifications, eating smaller meals, and remaining upright for a couple of hours after eating. Over-the-counter medications, such as antacids, H-2-receptor blockers, and proton pump inhibitors (PPIs), are also commonly recommended to neutralise or reduce stomach acid production. Initiating PPIs before meals, for example, half an hour beforehand, can be particularly effective in relieving acid reflux symptoms.
Furthermore, there is a potential link between long-term opioid use and the development of esophageal spasms. Recent research suggests that prolonged opioid use for three months or longer may increase the likelihood of experiencing esophageal spasms. However, more research is needed to establish a definitive causal relationship and identify specific risk factors.
In summary, acid reflux (GERD) is a condition characterised by the backflow of stomach contents into the oesophagus, which can potentially damage the nerves and trigger esophageal spasms. Treatment for acid reflux focuses on lifestyle modifications and medications to manage stomach acid levels and alleviate associated symptoms. Additionally, the link between acid reflux and esophageal spasms highlights the importance of effectively managing acid reflux to prevent or alleviate spasms and related complications.
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Extreme stress or anxiety
While the exact cause of esophageal spasms is not known, some believe that they occur due to faulty nerves that control how the muscles of the esophagus work. Esophageal spasms are sudden muscle contractions in the esophagus, the tube that connects the throat to the stomach. When the esophagus functions normally, a wave of coordinated contractions called peristalsis moves food or liquid down to the stomach. However, during esophageal spasms, these contractions become unusually powerful or ineffective, making it challenging for food or liquid to pass through the esophagus. This can lead to symptoms such as difficulty swallowing, chest pain, and regurgitation of food.
Anxiety-induced esophageal spasms can occur before, during, or after a period of nervousness, anxiety, fear, or stress. They can also vary in intensity and frequency, ranging from slight to severe and coming in waves. Additionally, they may precede, accompany, or follow an escalation of other anxiety sensations or symptoms.
It is important to note that esophageal spasms can be challenging to diagnose, as chest pain and swallowing difficulties are also symptoms of other conditions. Therefore, healthcare providers must first rule out heart-related issues and more common digestive system conditions before determining the presence of esophageal spasms.
If you suspect that extreme stress or anxiety is triggering your esophageal spasms, it is advisable to consult a healthcare professional. They can perform a physical examination, evaluate your symptoms, and provide guidance on managing both the spasms and your stress or anxiety.
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Certain foods and drinks, e.g. red wine, hot food
While the exact cause of oesophageal spasms is unknown, certain foods and drinks can trigger them. Oesophageal spasms are abnormal contractions in the oesophagus, the muscular tube that connects the mouth to the stomach. These spasms can make it difficult for food and liquids to reach the stomach, causing pain and discomfort.
Red wine is one of the beverages that have been linked to an increased risk of oesophageal spasms. While the specific reason for this connection is unclear, it is believed that the chemicals and compounds in red wine may contribute to it. Additionally, the temperature at which red wine is typically consumed could be a factor, as drinking very hot or cold liquids is a known trigger for oesophageal spasms.
Hot foods and beverages are also recognised triggers for oesophageal spasms. Consuming something that is very hot can cause the muscles in the oesophagus to contract abnormally, leading to spasms. This is why it is often recommended that individuals prone to oesophageal spasms allow hot foods and drinks to cool slightly before consumption.
In addition to temperature, the consistency of food can play a role in triggering oesophageal spasms. Eating food that has not been chewed thoroughly before swallowing can cause spasms. This is because large or poorly chewed pieces of food can disrupt the normal peristalsis, or coordinated contractions, of the oesophagus, leading to abnormal muscle contractions.
While the exact mechanisms are not fully understood, it is clear that certain dietary choices can increase the risk of oesophageal spasms. Identifying and avoiding specific triggers is an important part of managing this condition.
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Narcotic pain relievers (opiates)
Esophageal spasms are abnormal muscle contractions in the esophagus, which make it difficult for food and liquids to reach the stomach. They can cause chest pain and trouble swallowing. The exact cause of esophageal spasms is not known, but it is believed to be a type of motility disorder, which means there is a problem with how the muscles in the food pipe squeeze together to move food through the gastrointestinal system.
Opiates are narcotic pain relievers that work by binding to opioid receptors in the brain and body, blocking pain signals and reducing the perception of pain. While they can be effective in managing pain, they also come with a range of side effects, including the potential to cause esophageal spasms.
The exact mechanism by which opiates cause esophageal spasms is not fully understood. However, it is believed that it may be related to the way opiates interact with the nervous system and muscle contractions. Opiates can affect nerve signaling and muscle function, which may contribute to the development of esophageal spasms.
It is important to note that esophageal spasms can be challenging to diagnose and treat. If you are experiencing symptoms such as chest pain and difficulty swallowing, it is important to seek medical advice. A healthcare provider can evaluate your symptoms, rule out other potential causes, and recommend appropriate treatments or further investigations.
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Frequently asked questions
Esophageal muscle spasms are painful, abnormal muscle contractions that occur within the esophagus, the muscular tube that connects your mouth to your stomach. These spasms can make it difficult for food or liquid to move through the esophagus and may cause regurgitation.
The exact cause of esophageal muscle spasms is unknown, but they are believed to be related to faulty nerves that control how the esophageal muscles work. Certain foods and drinks, stress, and anxiety can trigger spasms. Recent research also suggests that long-term use of opioids and proton pump inhibitors may increase the likelihood of developing esophageal spasms.
Treatment for esophageal muscle spasms typically involves medication, lifestyle changes, and home remedies. Peppermint oil, a smooth muscle relaxant, is often recommended to calm down spasms. If conservative treatments are ineffective, myotomy surgery may be considered to weaken the esophageal contractions.











































