
Muscle fasciculation, also known as muscle twitching, is a spontaneous, involuntary muscle contraction and relaxation. It involves fine muscle fibres and can occur in any skeletal muscle in the body. Fasciculations are common, with up to 70% of people experiencing them. They can be benign or associated with more serious conditions, such as amyotrophic lateral sclerosis (ALS) or Lou Gehrig's disease.
| Characteristics | Values |
|---|---|
| Definition | A spontaneous, involuntary muscle contraction and relaxation, involving fine muscle fibres |
| Other names | Muscle twitch, fasciculation |
| Cause | Spontaneous depolarisation of a lower motor neuron |
| Occurrence | Common, with as many as 70% of people experiencing them |
| Detection | Surface electromyography (EMG) is the most effective way to detect fasciculations |
| Seriousness | Can be benign or associated with more serious conditions, such as amyotrophic lateral sclerosis (ALS) |
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What You'll Learn
- Muscle twitches are fine movements of a small area of muscle
- Fasciculations are caused by minor muscle contractions in the area
- Fasciculations can be benign or associated with more serious conditions
- The most effective way to detect fasciculations is surface electromyography (EMG)
- Fasciculations are caused by spontaneous depolarisation of a lower motor neuron

Muscle twitches are fine movements of a small area of muscle
Muscle twitching is caused by minor muscle contractions in the area, or uncontrollable twitching of a muscle group that is served by a single motor nerve fibre. Fasciculations occur when innervation from the peripheral nervous system to the muscle is not working correctly, causing a muscle to be triggered involuntarily. This can be caused by stimulation of the body, such as caffeine, excitement, stress, or anything that increases adrenaline. In the case of eye twitching, it could be due to general fatigue of the eye muscles.
Fasciculations arise as a result of spontaneous depolarisation of a lower motor neuron, leading to the synchronous contraction of all the skeletal muscle fibres within a single motor unit. Deeper areas of contraction can be detected by electromyography (EMG) testing, though they can happen in any skeletal muscle in the body.
Fasciculations in conjunction with other muscle-related symptoms can be indicative of a serious neurologic illness, such as amyotrophic lateral sclerosis (ALS), also called Lou Gehrig's disease, or anything else that damages nerves. If you are experiencing new muscle twitching as well as other issues in the same muscle, it is recommended that you discuss your symptoms with your doctor.
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Fasciculations are caused by minor muscle contractions in the area
Muscle fasciculation is a spontaneous, involuntary muscle contraction and relaxation, involving fine muscle fibres. Fasciculations are caused by minor muscle contractions in the area, or uncontrollable twitching of a muscle group that is served by a single motor nerve fibre. They are very common, with as many as 70% of people experiencing them. They can be benign, or associated with more serious conditions.
Fasciculations occur when innervation from the peripheral nervous system to the muscle is not working correctly and a muscle is triggered involuntarily, causing it to twitch. This can be caused by stimulation of the body, such as caffeine, excitement, stress, or anything that increases adrenaline. In the case of eye twitching, it could be due to general fatigue of the eye muscles.
Fasciculations arise as a result of spontaneous depolarisation of a lower motor neuron, leading to the synchronous contraction of all the skeletal muscle fibres within a single motor unit. They can be indicative of a serious neurologic illness, such as amyotrophic lateral sclerosis (ALS), also called Lou Gehrig's disease, or anything else that damages nerves. If you are experiencing new muscle twitching, it is recommended that you discuss your symptoms with your doctor.
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Fasciculations can be benign or associated with more serious conditions
Fasciculations can be indicative of a serious neurologic illness, such as amyotrophic lateral sclerosis (ALS), also called Lou Gehrig's disease, or anything else that damages nerves. Dr Ondo warns that twitching in the tongue muscle is almost always abnormal. If you are experiencing new muscle twitching as well as other issues in the same muscle, it is recommended that you discuss your symptoms with your doctor.
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The most effective way to detect fasciculations is surface electromyography (EMG)
Muscle fasciculation is a spontaneous, involuntary muscle contraction and relaxation, involving fine muscle fibres. It is a common phenomenon, with up to 70% of people experiencing them. They can be benign or associated with more serious conditions such as amyotrophic lateral sclerosis (ALS).
The most effective way to detect fasciculations is surface electromyography (sEMG or EMG). This technique involves measuring the electrical activity produced by muscles throughout the body using electrodes on the surface of the skin or inserted in the muscle. sEMG is a non-invasive measure of muscle activity that is widely used in research but under-utilised as a clinical tool in rehabilitative medicine. It is more sensitive than needle electromyography and clinical observation in the detection of fasciculation in people with ALS.
Surface EMGs can detect deeper areas of contraction and convey information regarding muscle activation, such as the intensity of muscle contraction and the myoelectric manifestation of muscle fatigue. The process involves computer analysis of the frequency spectrum, amplitude, or root mean square of the electrical action potential.
SEMG is occasionally used as an aid to diagnose neuromuscular disorders, determine the need for surgery in individuals with low back pain, and assist in evaluating the prognosis of disorders involving muscle lesions. It has also been used to monitor the effects of rehabilitation programs and evaluate muscular function in occupational and sports programs.
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Fasciculations are caused by spontaneous depolarisation of a lower motor neuron
Muscle fasciculation is a spontaneous, involuntary muscle contraction and relaxation, involving fine muscle fibres. It is also known as a muscle twitch. Fasciculations are caused by spontaneous depolarisation of a lower motor neuron, leading to the synchronous contraction of all the skeletal muscle fibres within a single motor unit.
Fasciculations occur when innervation from the peripheral nervous system to the muscle is not working correctly, causing a muscle to twitch involuntarily. The biochemical mechanism behind this is not fully understood, but Dr Ondo suggests that stimulation of the body, such as caffeine, excitement, stress or anything that increases adrenaline, may make fasciculations more likely.
Fasciculations are very common, with as many as 70% of people experiencing them. They can be benign, or associated with more serious conditions. When no cause or pathology is identified, they are diagnosed as benign fasciculation syndrome. However, fasciculations in conjunction with other muscle-related symptoms can be indicative of a serious neurological illness, such as amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, or anything else that damages nerves.
The most effective way to detect fasciculations may be surface electromyography (EMG), which is more sensitive than needle electromyography and clinical observation in the detection of fasciculation in people with ALS.
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Frequently asked questions
Muscle fasciculation is a spontaneous, involuntary muscle contraction and relaxation, involving fine muscle fibres.
Muscle fasciculation occurs when innervation from the peripheral nervous system to the muscle is not working correctly, causing a muscle to twitch involuntarily. This can be caused by anything that increases adrenaline, such as caffeine, excitement or stress.
Muscle fasciculation is very common, with as many as 70% of people experiencing them. They often go unnoticed.
Muscle fasciculation can be benign, or associated with more serious conditions. When occurring with other muscle-related symptoms, it can be indicative of a serious neurological illness, such as amyotrophic lateral sclerosis (ALS).









































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