
The human body contains three types of muscle tissue: skeletal, smooth, and cardiac. Skeletal muscles are attached to bones and allow movement. They also prevent excess movement of the bones and joints, maintaining skeletal stability and preventing skeletal structure damage or deformation. Smooth muscles are found in the walls of internal organs and are responsible for involuntary muscle movements such as breathing. Cardiac muscles are found in the heart and are responsible for pumping blood throughout the circulatory system.
| Characteristics | Values |
|---|---|
| Types | Skeletal muscle, cardiac muscle, and smooth muscle |
| Basic Function | Create movement |
| Appearance | Skeletal muscle is visible just under the skin, especially in the limbs. Cardiac muscle is similar in appearance to skeletal muscle. |
| Function of Skeletal Muscle | Produce movement, stop movement, maintain posture, protect internal organs, control functions like swallowing, urination, and defecation |
| Function of Smooth Muscle | Responsible for involuntary muscle movement, present in walls of hollow organs, passageways, tracts of the respiratory, urinary, and reproductive systems, eyes, and skin |
| Function of Cardiac Muscle | Highly coordinated contractions to pump blood throughout the circulatory system |
| Largest Muscle | Gluteus Maximus |
| Hardest Working Muscle | Heart |
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What You'll Learn

Smooth muscle: Involuntary movement, e.g. breathing
The human body contains three types of muscle tissue: skeletal, smooth, and cardiac. Smooth muscles are found in various internal organs and work automatically without conscious control, making them responsible for involuntary contractions that aid in digestion, regulate blood flow, and control breathing. Smooth muscles lack the striated structure of skeletal muscles and instead consist of sheets or layers of smooth muscle cells. When stimulated by the autonomic nervous system, smooth muscle cells contract, and their shortening is caused by the movement of actin and myosin myofilaments.
Smooth muscles are involved in automatic internal processes needed for survival, controlling blood vessels and organs like the heart, lungs, and digestive system. They are responsible for the involuntary movement of breathing, which is an essential function of the human body. The diaphragm and external intercostals are the primary inspiratory muscles, aiding inhalation by expanding the thoracic cavity. Conversely, expiratory muscles induce exhalation by compressing the thoracic cavity.
The contraction and relaxation of smooth muscles are regulated by the autonomic nervous system, which controls the activity of organs and blood vessels required for essential daily functions like digestion and breathing. Smooth muscles are distinct from skeletal muscles, which are under voluntary control and produce both movement and the stopping of movement, such as resisting gravity to maintain posture. Skeletal muscles are attached to bones and can be consciously controlled to perform actions like walking or lifting.
In summary, smooth muscles are a vital component of the human body, facilitating involuntary movements like breathing through their automatic contractions and relaxations. They work in tandem with other muscle types and the nervous system to ensure the body's survival and proper functioning.
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Cardiac muscle: Heart muscle, responsible for pumping blood
The body contains three types of muscle tissue: skeletal muscle, cardiac muscle, and smooth muscle. Cardiac muscle, also known as heart muscle or myocardium, is an involuntary, striated muscle that makes up the heart wall's middle layer. It is responsible for the heart's pumping action, facilitating blood circulation.
Cardiac muscle cells, or cardiomyocytes, are tubular structures composed of chains of myofibrils—rod-like units within the cell. Myofibrils consist of repeating sections of sarcomeres, the fundamental contractile units of muscle cells. Sarcomeres are made up of long proteins that form thick and thin filaments called myofilaments. The sliding of these filaments past each other during muscle contraction generates force, resulting in the heart's pumping action.
The coordination of cardiac muscle cells is essential for effective blood pumping. Neighbouring cardiomyocytes are connected by intercalated discs, forming a functional syncytium. This network enables the rapid transmission of electrical impulses, ensuring synchronized contraction of the myocardium. The Purkinje fibres within the cardiac muscle rapidly conduct electrical signals, contributing to the coordinated contractions.
Cardiac muscle cells also contain specialized pacemaker cells that set the rhythm of heart contractions. These cells generate and transmit electrical impulses, determining the heart's beating pattern. The functioning of cardiac muscle depends on adequate blood supply via coronary circulation. Diseases affecting cardiac muscle, such as ischemic heart disease, can have severe health consequences, emphasizing the critical role of this muscle tissue in maintaining overall health.
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Skeletal muscle: Controls movement and maintains posture
Skeletal muscle is the most common type of muscle in the human body, accounting for around 30% to 40% of total body mass. These muscles are attached to bones by tendons and allow for a wide range of movements and functions. They are under voluntary control, meaning that we can consciously decide how and when they work. Skeletal muscles are responsible for producing movement and also for stopping movement, such as resisting gravity to maintain posture.
The skeletal muscle is made up of bundles of muscle fibres called myofibers, which contain several myofibrils. These fibres contract, allowing the muscles to move bones and enabling various movements. Each muscle can contain thousands of fibres, and these fibres are surrounded by connective tissue layers called fascia. Skeletal muscles are also responsible for protecting internal organs by acting as an external barrier to trauma and supporting the weight of organs like the abdominal and pelvic organs.
The maintenance of body posture and position is a key function of skeletal muscle. Small, constant adjustments of these muscles are needed to hold the body upright or balanced in any position. They also prevent excess movement of the bones and joints, maintaining skeletal stability and preventing damage or deformation. Deeper muscles involved in posture are controlled from nuclei in the brain stem and basal ganglia.
Skeletal muscles also play a role in controlling the movement of various substances in the body. They are located at the openings of internal tracts and allow functions like swallowing, urination, and defecation to be under voluntary control. Additionally, skeletal muscles contribute to basal energy metabolism, serving as a storage site for essential substrates such as carbohydrates and amino acids.
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Muscle contractions: Cause movement of fluids and substances
Muscle contractions are essential for movement and the functioning of the human body. The body contains three types of muscle tissue: skeletal muscle, cardiac muscle, and smooth muscle. Skeletal muscles are attached to bones and play a crucial role in producing movement, maintaining posture, and controlling the movement of various substances and functions in the body. For example, skeletal muscles enable us to perform voluntary actions such as swallowing, urination, and defecation. They also provide structural support, protect internal organs, and prevent damage to the skeletal structure.
Cardiac muscle, or myocardium, is responsible for the pumping of blood and giving us our heartbeat. It has a similar appearance to skeletal muscle but serves a distinct function. Cardiac muscle comprises the walls of the heart, allowing blood to be pumped through the vasculature.
Smooth muscle, the third type of muscle tissue, is found throughout the body in various organs and systems, including the blood vessels, gastrointestinal tract, bronchioles, uterus, and bladder. Smooth muscle cells can be classified into two types: single-unit and multiunit. Single-unit smooth muscle cells are linked together via gap junctions and are found in the gut and blood vessels, allowing for contraction as a functional syncytium. Multiunit smooth muscle cells, on the other hand, are found in the muscles of the eye and at the base of hair follicles.
The process of muscle contraction involves the activation of tension-generating sites within muscle cells. This activation triggers chemical reactions that lead to the reorganisation of muscle fibres, resulting in a shortening of the muscle and subsequent relaxation upon signal cessation. Muscle contractions can be described in terms of variables such as length and tension. For example, a concentric contraction occurs when a muscle shortens, like when bending the elbow, while an eccentric contraction involves the lengthening of muscle fibres, such as during downhill walking.
The mechanism of muscle contraction can be summarised in three steps. Firstly, a message is sent from the nervous system to the muscular system, triggering chemical reactions. Secondly, these chemical reactions lead to the reorganisation of muscle fibres, resulting in muscle contraction. Finally, when the nervous system signal stops, the chemical process reverses, the muscle fibres rearrange, and the muscle relaxes.
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Muscle damage: Radiotherapy can cause fibrosis, shortening, and atrophy
The human body contains three types of muscle tissue: skeletal, smooth, and cardiac. Skeletal muscles are attached to bones and allow for movement, stability, and protection of internal organs. Cardiac muscles, also known as the myocardium, are responsible for the heart's pumping action. Smooth muscles, meanwhile, are found in the walls of organs and play a role in involuntary processes such as digestion.
Radiotherapy, a common treatment for cancer, can cause muscle damage in the form of fibrosis, shortening, and atrophy. This damage is particularly prevalent in juvenile cancer survivors, with studies showing that 80% of childhood cancer survivors experience muscle atrophy and fibrosis. The mechanisms behind radiation-induced muscle fibrosis are complex and involve the activation of various cell types, such as fibroblasts, endothelial cells, and vascular smooth muscle cells, which transform into myofibroblasts. These myofibroblasts secrete excessive amounts of extracellular matrix components, leading to tissue stiffening and dysfunction.
Radiation-induced muscle atrophy is also a significant consequence of radiotherapy. Atrophy refers to the wasting away or shrinking of muscle tissue. In the context of radiotherapy, atrophy occurs due to the depletion of muscle satellite (stem) cells and the impairment of their differentiation and fusion. This results in a decrease in muscle mass and function, contributing to long-term complications in cancer survivors.
Additionally, radiotherapy can cause muscle shortening, which may lead to a reduced range of motion and flexibility. This shortening is likely a result of the fibrotic changes in the muscle tissue, as fibrosis can cause the tissue to become stiff and contracted. While the exact mechanisms are still being studied, it is clear that radiotherapy can induce muscle damage that persists long after the initial treatment.
The understanding of radiation-induced muscle damage is crucial for developing targeted therapies and improving the quality of life for cancer survivors. By recognizing and addressing these adverse effects, healthcare professionals can provide better support and management strategies to mitigate the impact of muscle damage on patients' overall health and well-being.
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Frequently asked questions
The three types of muscle tissue are skeletal muscle, cardiac muscle, and smooth muscle.
Skeletal muscles are located throughout the body and are under voluntary control. They produce movement of the arms, legs, back, and neck, and maintain posture by resisting gravity.
Cardiac muscle is only found in the heart. Highly coordinated contractions of cardiac muscle pump blood throughout the circulatory system.
Smooth muscle is mainly associated with the walls of internal organs. It is responsible for involuntary muscle movement, such as breathing.











































