
Striated muscle tissue is a type of muscle tissue that features repeating functional units called sarcomeres. These sarcomeres are visible under a microscope, appearing as stripes along muscle fibres. The two types of striated muscle tissue are skeletal muscle and cardiac muscle. Skeletal muscle is attached to the bones by tendons and is responsible for the voluntary movements of bones. Cardiac muscle, on the other hand, is found on the walls of the heart and is responsible for heart contractions.
| Characteristics | Values |
|---|---|
| Muscle Tissue Types | Skeletal Muscle, Cardiac Muscle |
| Muscle Tissue Appearance | Striated |
| Muscle Tissue Components | Sarcomeres, T-Tubules, Skeletal Muscle Fibers, Blood Vessels, Nerve Fibers, Connective Tissue |
| Skeletal Muscle Wrapping | Epimysium |
| Muscle Fiber Components | Sarcolemma, Sarcoplasm, Sarcoplasmic Reticulum, Myofibrils |
| Myofibril Composition | Actin, Myosin |
| Sarcomere Composition | Actin Filaments, Myosin Filaments |
| Sarcomere Function | Contraction of Muscle |
| Muscle Cell Nuclei | Many, Placed at Regular Intervals |
| Muscle Cell Classification | Slow-Oxidative (Type I), Fast-Oxidative (Type II) |
| Cardiac Muscle Cell Nuclei | One, Centrally Located |
| Muscle Cell Mitochondria | Many |
| Muscle Cell Myoglobin | Present |
| Skeletal Muscle Attachment | Bones, Tendons |
| Skeletal Muscle Functions | Movement, Breathing, Posture Maintenance |
| Cardiac Muscle Functions | Heart Contraction, Blood Pumping |
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Skeletal muscle
The development of skeletal muscles in the limbs and trunk depends on the expression of MyoD and Myf5 and their effects on the different myoblasts. Embryonic myoblasts undergo further differentiation to form primary muscle fibres and eventually secondary myofibers by the union of myoblasts in the fetus. After birth, satellite cells act as stem cells and are responsible for the further growth and development of skeletal muscles.
The primary artery supplying blood to a skeletal muscle generally courses parallel to the longitudinal axis of the muscle fibre. The feed artery branches into primary arterioles, which give rise to transverse arterioles and then terminal arterioles. The terminal arterioles perfuse the capillaries that are present within the endomysium and travel parallel to the longitudinal axis of the muscle fibre.
The neuronal innervation of a skeletal muscle typically comprises sensory nerve fibres, motor nerve fibres, and the neuromuscular junction. The nerve fibres are composed of myelinated as well as non-myelinated nerve fibres. The cell bodies of neurons give rise to large axons, which travel to the target muscles for innervation.
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Cardiac muscle
The main function of cardiac muscle is to pump blood into circulation by generating sufficient force. The mechanism behind each coordinated contraction involves the cardiac muscle and electrical impulses. These contractile functions of the heart require ATP, which can be obtained through various substrates, including fatty acids, carbohydrates, proteins, and ketones. Electrical stimulation in the form of a cardiac action potential triggers the release of calcium from the cell's internal calcium store, the sarcoplasmic reticulum. The Purkinje fibres rapidly conduct electrical signals, while coronary arteries bring nutrients to the muscle cells, and veins and a capillary network take away waste products.
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Muscle contraction
There are three types of muscles in mammals: skeletal, cardiac, and smooth. Skeletal muscles are attached to bones and provide the body with structure and strength. They are responsible for the body's voluntary movements. Cardiac muscles, on the other hand, are found in the walls of the heart and facilitate the pumping of blood through the vasculature. Smooth muscles are found in the blood vessels, gastrointestinal tract, bronchioles, uterus, and bladder.
Skeletal muscles are composed of muscle fibres and connective tissue layers. These muscle fibres contain actin and myosin filaments that power contraction. The actin filaments are attached to the Z-line, found in the middle of the I-bands, and the area between two Z-lines forms a functional unit called the sarcomere. The myosin filaments bind to the actin filaments through cross-bridges, and the ATP-dependent rowing motion of the myosin heads causes a shift of the actin filaments, resulting in muscle contraction.
The contraction of skeletal muscles is neurogenic, requiring synaptic input from motor neurons. A single motor neuron can innervate multiple muscle fibres, causing them to contract simultaneously. Once innervated, the protein filaments within each skeletal muscle fibre slide past each other to produce a contraction, as described by the sliding filament theory.
Cardiac muscle contractions, on the other hand, are myogenic and initiated by the heart muscle cells themselves. They occur due to a myogenic response of the heart's pacemaker cells, which respond to signals from the autonomic nervous system to regulate heart rate.
Smooth muscle contractions, like cardiac muscle contractions, are also myogenic. Smooth muscle fibres do not contain sarcomeres but use actin and myosin contraction to constrict blood vessels and move the contents of hollow organs in the body. These contractions are involuntary and regulated by reflexes and the body's autonomic nervous system.
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Muscle atrophy
The two types of striated muscle are skeletal muscle and cardiac muscle. Skeletal muscle is responsible for the voluntary movements of bones and is attached to the components of the skeleton. It includes skeletal muscle fibers, blood vessels, nerve fibers, and connective tissue. Cardiac muscle, on the other hand, is found in the walls of the heart and is responsible for heart contractions. Both skeletal and cardiac muscle cells have multiple nuclei, while cardiac muscle cells are unicellular and have a single, centrally located nucleus.
The main function of striated muscle tissue is to create force and contract. In skeletal muscle, contractions enable breathing, movement, and posture maintenance. In cardiac muscle, contractions pump blood throughout the body. The striated appearance of these muscles is due to the densely packed myofibrils within them. The functional unit of a muscle fiber is called a sarcomere, which consists of repeating units of actin and myosin myofilaments. The contraction of the muscle occurs through the ATP-dependent rowing motion of the myosin heads, causing a shift of the actin filaments.
The treatment and management of muscle atrophy aim to restore muscle mass and function and prevent further deterioration. Exercise is a crucial component of treatment, as it helps stimulate muscle growth and improve strength. Physical therapy can be tailored to the specific needs and limitations of the individual, and exercises in a swimming pool can reduce the muscle workload during rehabilitation. Additionally, nutritional therapy is important, especially in cases of malnutrition or starvation, to promote muscle growth and repair.
In some cases, medical interventions may be necessary. Ultrasound therapy can be used to promote tissue healing and reduce inflammation. Surgery may be considered to correct contractures or address underlying conditions contributing to muscle atrophy. Anabolic agents, although not frequently used due to side effects, may be explored in specific cases to promote muscle growth.
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Muscle fascicles
Fascicles are further grouped to form a muscle, which is encased by a fibrous tissue envelope called the epimysium. The epimysium is a tight connective tissue that separates the muscle from surrounding structures. It is contiguous with the perimysial septa that separate the fascicles. The perimysium and epimysium are the densest connective tissues in the muscle.
The muscle fascicle structure is a useful diagnostic tool for dermatomyositis. Myocytes towards the edges of the muscle fascicle are typically narrower, while those at the centre are of normal thickness. Ultrasound examinations can be used to evaluate normal and pathologic states. The ultrasound appearance of muscle is affected by factors such as the angulation of the ultrasound beam, the state of contraction of the muscle, and the ratio of perimysium to fascicles.
Skeletal muscle is a type of striated muscle tissue that is composed of bundles of muscle fibres called myofibers, which contain several myofibrils. Myofibrils are composed of actin (thin filaments), myosin (thick filaments), and support proteins. The arrangement of actin and myosin gives skeletal muscle its microscopic striated appearance and creates functional units called sarcomeres.
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Frequently asked questions
Striated muscle tissue is a muscle tissue that features repeating functional units called sarcomeres. Under a microscope, sarcomeres are visible along muscle fibres, giving a striated appearance to the tissue.
The two types of striated muscle are skeletal muscle and cardiac muscle.
Skeletal muscle is the tissue that most muscles attached to bones are made of. Skeletal muscles are attached to bones by tendons and produce all the movements of body parts in relation to each other.
Cardiac muscle is the muscle found on the walls of the heart. Cardiac muscle cells are generally unicellular and are connected to each other by intercalated discs.
Sarcomeres are the functional units of muscle fibres. They are composed of actin and myosin myofilaments. The area between two Z-lines, where actin filaments are attached, makes up a sarcomere.











































