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Prolia (denosumab) is a prescription medicine used to treat osteoporosis and prevent bone fractures in people with breast or prostate cancer. It is also used to increase bone mass in people at high risk of fractures. While Prolia can be effective, it has been known to cause several side effects, ranging from mild to severe, with the most common being joint pain, back pain, pain in the arms and legs, and muscle pain.
| Characteristics | Values |
|---|---|
| Muscle pain | Very common |
| Joint pain | Very common |
| Back pain | Very common |
| Pain in arms and legs | Common |
| Thigh bone fractures | Rare |
| Allergic reactions | Rare |
| Increased risk of infection | Yes |
| Increased risk of broken bones | Yes |
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What You'll Learn
Prolia can cause bone, joint, and muscle pain
Prolia (denosumab) is a prescription medicine used to treat osteoporosis, a condition where bones become weaker and are more likely to break. It is also used to prevent bone fractures in people with breast or prostate cancer who are taking certain medications.
If you experience bone, joint, or muscle pain while taking Prolia, it is important to contact your doctor or healthcare provider right away. They may recommend treatment for your pain or suggest that you stop using Prolia and try a different medication. Do not stop taking Prolia without first consulting your doctor, as stopping the medication can increase your risk of bone fractures, including in the spine.
Prolia may also cause other side effects, including an increased risk of serious infections, skin problems, and low blood calcium levels (hypocalcemia). Some people may also experience an allergic reaction to Prolia, which can be serious and requires immediate medical attention. It is important to discuss the potential benefits and risks of Prolia treatment with your doctor before starting the medication.
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Thigh bone fractures may cause joint pain
Prolia (denosumab) is an injection prescribed for certain adults with osteoporosis, a condition that causes bones to weaken. It is also used to prevent bone fractures in people with breast or prostate cancer who are taking certain medications. Prolia is known to have several side effects, ranging from mild to severe. One of the rare but serious side effects of Prolia is unusual fractures in the thigh bone or femur, the largest bone in the human body.
Thigh bone fractures can be extremely painful and cause the leg to look bent or floppy, making it impossible to walk. These fractures often require surgery and the use of metal plates, screws, or rods to hold the broken bone in place. The recovery process can be lengthy, typically taking three to six months or even longer in some cases. During this period, physical therapy and exercises are crucial to restore muscle strength, joint motion, and flexibility.
Symptoms of a thigh bone fracture include new or unusual sensations of pain in the hip, thigh, or groin area. This pain can occur before the actual fracture, with some people experiencing a dull, aching pain weeks or even months in advance. If you experience any of these symptoms while taking Prolia, it is important to contact your doctor immediately. They may recommend temporarily discontinuing Prolia and evaluating the risks and benefits of continuing the medication.
Fractures, including those in the thigh bone, can cause joint pain. This joint pain may be mild or severe and can occur even when the fracture is not directly in the joint. If you experience joint pain due to a thigh bone fracture, your doctor may suggest treatment options for pain management and could recommend discontinuing Prolia and exploring alternative medications.
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Prolia may cause allergic reactions
Prolia (denosumab) is a prescription medicine used to treat osteoporosis and prevent bone fractures in people with breast or prostate cancer. It is also used to increase bone mass in people with osteoporosis and those at high risk of bone fractures.
If you experience any symptoms of an allergic reaction while taking Prolia, seek medical advice immediately. It is important to report negative side effects of prescription drugs to the relevant authorities, such as the FDA in the United States.
In addition to allergic reactions, Prolia may also cause other side effects such as joint pain, muscle pain, back pain, pain in the arms and legs, and increased risk of bone fractures, particularly in the spine. Some people have also reported unusual thigh bone fractures while taking Prolia, which can cause new or unusual pain in the hip, groin, or thigh area.
It is important to note that not all possible side effects of Prolia have been identified, and individual experiences may vary. Therefore, it is always advisable to consult a healthcare professional before starting any new medication to understand the potential benefits and risks.
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Prolia may increase the risk of infection
Prolia (denosumab) is a prescription medicine used to treat osteoporosis, a condition where bones become weaker and are more likely to break. It is also used to prevent bone fractures in people with breast or prostate cancer who are taking certain medications. Prolia is administered as an injection by a healthcare professional once every six months.
Prolia may increase the risk of developing serious infections, including skin, bladder, ear, and lower stomach infections. It may also cause endocarditis, an infection of the heart lining. Patients taking Prolia should be vigilant about any potential symptoms of infection and contact their doctor immediately if they experience any of the following:
- Fever or chills
- Red, swollen skin
- Severe abdominal or stomach pain
- Burning or painful urination
- Numbness or tingling in the fingers, toes, or around the mouth
- Muscle twitches or spasms
It is important to note that Prolia can also cause severe bone, joint, or muscle pain. Some people who take Prolia develop severe pain in these areas, which can last for days, weeks, or even months. If you experience any severe pain, it is important to consult your healthcare provider right away.
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Prolia may cause low blood calcium levels
Prolia (denosumab) is a prescription medicine used to treat osteoporosis, a condition where bones weaken and become more susceptible to fractures. It is also used to prevent bone fractures in patients with breast or prostate cancer who are taking certain medications.
To avoid low blood calcium levels, it is recommended that people taking Prolia take calcium (1,000-1,200 mg) and vitamin D (at least 400 IU) daily. However, these doses should be confirmed with a healthcare provider before starting treatment.
Prolia has also been associated with other side effects, including bone, joint, and muscle pain. Some people who take Prolia develop severe bone, joint, or muscle pain. Fractures, particularly in the thigh bone, have been observed in some patients taking Prolia, which can cause joint pain even when the fracture is not in the joint itself. If you experience new or unusual pain in your hip, thigh, or groin, contact your doctor immediately. They may recommend that you stop using Prolia and switch to a different medication.
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Frequently asked questions
Yes, joint pain is a possible side effect of Prolia. Joint pain can be a symptom of a fracture, even when the fracture isn't in the joint itself.
Yes, Prolia can cause muscle pain and aches.
If you experience joint or muscle pain while taking Prolia, talk to your doctor. They may recommend treatment for the pain or advise you to stop using Prolia and switch to a different medication.
Prolia can cause mild to severe side effects, including low blood calcium (hypocalcemia), serious allergic reactions, skin problems, increased risk of infections, and unusual thigh bone fractures.
