
Epaxial muscles are a type of skeletal muscle found in vertebrates. They are defined by their innervation by the dorsal rami of spinal nerves and their position relative to the vertebral column. Epaxial muscles are derived from the medial halves of somites and are restricted to the intrinsic back muscles, while hypaxial muscles are derived from the lateral somitic halves and consist of a heterogeneous group of intercostal, abdominal, limb, and girdle muscles. The distinction between epaxial and hypaxial muscles is important in understanding the evolution and development of skeletal musculature in vertebrates.
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What You'll Learn

Epaxial muscles are made up of the intrinsic (deep) back muscles
In vertebrates, skeletal muscles are made up of epaxial and hypaxial muscles, which are defined by their innervation and relative position to the vertebral column. Epaxial muscles are innervated by the dorsal branches of the spinal nerves and comprise the intrinsic (deep) back muscles, while the hypaxial muscles are innervated by the ventral branches of the spinal nerves and consist of a heterogeneous group of intercostal, abdominal, limb, and girdle muscles. The epaxial muscles are derived from the medial halves of the somites, while the hypaxial muscles originate from the lateral somitic halves.
The epaxial muscles are restricted to the intrinsic back muscles dorso-lateral to the vertebral column. They are involved in maintaining posture and include the iliocostalis system (lumborum and thoracis regions), the longissimus system (lumborum, thoracis, cervicis, and capitis), and the transversospinalis system (especially large in the neck). The transversospinalis system includes the splenius muscle and the semispinalis capitis muscle, which has two parts: the biventer cervicis muscle and the complexus muscle.
The hypaxial muscles, on the other hand, are involved in locomotion, prey-capturing, and respiration. They include muscles in the lateral body wall, such as the deep-shoulder muscles and some body wall muscles. The hypaxial somites also contribute to the mammalian diaphragm, a vital component of the respiratory system.
The distinction between epaxial and hypaxial muscles is important in understanding the development and evolution of skeletal muscles in vertebrates. The somites, which are different compartments of the embryo, give rise to the epaxial and hypaxial muscles. The dorsomedial compartment generates the epaxial myotome, while the ventrolateral compartment gives rise to the hypaxial myotome. This distinction is more conspicuous in cartilaginous and bony fish, where the two compartments are separated by the horizontal myoseptum, a connective tissue sheet located on either side of the notochord.
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They are innervated by the dorsal branches of spinal nerves
Epaxial muscles are those associated with the vertebrae, ribs, and base of the skull. In humans, the only epaxial muscles are the erector spinae, the transversospinales (including the multifidus, semispinalis and rotatores), the splenius, and the suboccipital muscles. These muscles are considered "deep" or "intrinsic" back muscles.
The epaxial muscles are innervated by the dorsal rami of the spinal nerves. The spinal nerves split into dorsal and ventral rami just after the joining of the dorsal sensory and ventral motor roots from the spinal cord. The dorsal rami then divide into medial, intermediate, and lateral branches. The lateral branch supplies innervation to the iliocostalis muscle and the skin on the back. The intermediate branch supplies innervation to the spinalis and longissimus muscles. The medial branch supplies innervation to the rest of the epaxial muscles on the back, including the transversospinales, intertransversarii, interspinalis, suboccipital, and splenius muscles, as well as the zygapophyseal joints.
The dorsal rami provide motor innervation to the deep muscles of the back and sensory innervation to the skin of the posterior portion of the head, neck, and back. In the neck and upper back, the medial branch is responsible for providing sensory innervation to the skin, while in the lower back, the lateral branch does so. All medial branches also provide sensory innervation to the zygapophyseal joints and periosteum of the vertebral column.
The traditional distinction between epaxial and hypaxial muscles, based on their innervation by the dorsal and ventral rami of the spinal nerve, does not correspond to the primaxial and abaxial muscle distinction defined by the mesodermal lineages of target tissues. To address this discrepancy, a three-component model of spinal nerve ramification has been proposed, which incorporates findings from both human gross anatomy and modern embryology.
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Epaxial muscles are derived from the medial halves of somites
The epaxial and hypaxial muscles are two types of skeletal muscles in vertebrates, distinguished by their innervation and relative position to the vertebral column. Epaxial muscles are located dorso-lateral to the vertebral column and are innervated by the dorsal branches of the spinal nerves, while hypaxial muscles are located in the lateral body wall and are innervated by the ventral branches of the spinal nerves.
The epaxial muscles, arising from the medial halves of the somites, form the intrinsic or deep back muscles. These include muscles in the iliocostalis system (lumborum and thoracis regions), longissimus system (lumborum, thoracis, cervicis, and capitis), and transversospinalis system, particularly prominent in the neck region.
The embryological development of epaxial muscles has been studied using quail-chick chimeras and grafting experiments, revealing the important role of somites and their compartments in muscle formation. The dorsomedial compartment of the somites, or the epaxial myotome, provides the material for the development of epaxial muscles, contributing to the body's intrinsic back muscles.
In summary, epaxial muscles are derived from the medial halves of somites, specifically the dorsomedial compartment known as the epaxial myotome. This developmental process contributes to the formation of the intrinsic back muscles in vertebrates, including muscles in the iliocostalis, longissimus, and transversospinalis systems.
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They are restricted to the intrinsic back muscles
Epaxial muscles are a category of skeletal muscle in vertebrates, alongside hypaxial muscles. They are defined by their innervation by the dorsal rami of spinal nerves and their relative position to the vertebral column. Epaxial muscles are restricted to the intrinsic back muscles, which are deep and dorso-lateral to the vertebral column.
The epaxial and hypaxial distinction is made based on the innervation of the muscles and their position relative to the vertebral column. Epaxial muscles are innervated by the dorsal branches of spinal nerves, while hypaxial muscles are innervated by the ventral branches. The hypaxial muscles include a heterogeneous group of intercostal, abdominal, limb, and girdle muscles.
The epaxial muscles are derived from the medial halves of the somites, specifically the dorsomedial compartment, while the hypaxial muscles are derived from the lateral somitic halves, or the ventrolateral compartment. The somites give rise to most of the skeletal muscle of the body and consist of different compartments. The epaxial myotome provides the material for the intrinsic muscles of the back.
The epaxial and hypaxial muscle groups are further subdivided into longitudinal systems. The epaxial muscles are divided into the iliocostalis system, the longissimus system, and the transversospinalis system. The hypaxial muscles are divided into the dorsalis scapulae and rhomboid muscles.
The distinction between epaxial and hypaxial muscles is more conspicuous in cartilaginous and bony fish, where the two compartments are separated by the horizontal myoseptum, a connective tissue sheet located on either side of the notochord. In fish, the horizontal myoseptum provides an attachment for trunk muscles to facilitate undulatory locomotion. In amniotes, such as mammals, birds, and reptiles, the distinction is made based on innervation patterns.
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Epaxial muscles are specialised for posture maintenance
Epaxial muscles are a type of skeletal muscle found in vertebrates. They are defined by their innervation by the dorsal rami of spinal nerves and their relative position to the vertebral column. Specifically, epaxial muscles are restricted to the intrinsic deep back muscles, located dorso-lateral to the vertebral column.
The epaxial and hypaxial muscles are two categories of trunk muscles in vertebrates. Epaxial muscles are located dorso-lateral to the vertebral column and are innervated by the dorsal branches of the spinal nerves. On the other hand, hypaxial muscles are located in the lateral body wall and are innervated by the ventral branches of the spinal nerves. The hypaxial muscles include a heterogeneous group of intercostal, abdominal, limb, and girdle muscles.
The epaxial muscles are essential for maintaining posture in amniotes, which include mammals, birds, and reptiles. They provide the structural support necessary for the body to maintain its position and balance. The deep back muscles that comprise the epaxial system contribute to the stability and control of the vertebral column, enabling the body to hold its posture.
The organisation of epaxial muscles can be further subdivided into three longitudinal systems: the iliocostalis system, the longissimus system, and the transversospinalis system. Each of these systems is then divided transversely per region. For example, the longissimus system includes the lumborum, thoracis, cervicis, and capitis regions.
The distinction between epaxial and hypaxial muscles is more pronounced in cartilaginous and bony fish. In fish, these muscle groups are separated by the horizontal myoseptum, a connective tissue sheet located on either side of the notochord. The coordinated contraction of these muscles allows for S-shaped swimming movements.
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Frequently asked questions
Epaxial muscles are the intrinsic (deep) back muscles in vertebrates. They are innervated by the dorsal branches of the spinal nerves.
Epaxial muscles are the intrinsic back muscles, while hypaxial muscles are a heterogeneous group of intercostal, abdominal, limb, and girdle muscles. They are innervated by the dorsal and ventral branches of the spinal nerves, respectively.
Epaxial muscles develop from the dorsal lips of the dermomyotomes, the myogenic compartment of the somites.











































