
Muscle atrophy is the wasting or thinning of muscle mass. It can be caused by several factors, including immobility, aging, malnutrition, medications, and various injuries or diseases affecting the musculoskeletal or nervous system. There are three main types of muscle atrophy: physiologic, pathologic, and neurogenic. Physiologic atrophy, also known as disuse atrophy, occurs when muscles are not used enough, leading to a decrease in size and strength. Pathologic atrophy is associated with aging, starvation, and diseases such as Cushing's disease. Neurogenic atrophy, the most severe form, is caused by nerve injuries or diseases that disrupt muscle contractions, resulting in rapid muscle breakdown and wasting. The treatment for muscle atrophy depends on the underlying cause and may include exercise, nutritional therapy, physical therapy, and in some cases, surgery.
| Characteristics | Values |
|---|---|
| Definition | Wasting or thinning of muscle mass |
| Loss of muscle mass | 20-40% |
| Muscle appearance | Smaller than normal |
| Muscle strength | Decreased |
| Muscle weakness | Increased |
| Limbs | Numbness, weakness, and tingling |
| Face or throat muscles | Weak facial muscles, difficulty swallowing or speaking |
| Causes | Malnutrition, age, genetics, lack of physical activity, nerve problems, diseases, inadequate nutrition, injury, illness, medications |
| Reversibility | Can be reversed with exercise, physical therapy, and nutritional therapy |
| Treatments | Physical therapy, ultrasound therapy, surgery, functional electric stimulation, anabolic agents, exercise, and adequate nutrition |
Explore related products
What You'll Learn
- Muscle atrophy is caused by immobility, ageing, malnutrition, medications, or injuries
- Physiologic atrophy occurs when muscles are not used enough
- Neurogenic atrophy is caused by nerve problems or diseases
- Malnutrition-related atrophy can be caused by conditions that impair nutrient absorption
- Muscle atrophy can be treated with physical therapy, functional electric stimulation, or surgery

Muscle atrophy is caused by immobility, ageing, malnutrition, medications, or injuries
Muscle atrophy is the wasting or thinning of muscle mass. It can be caused by immobility, ageing, malnutrition, medications, or injuries.
Immobilisation due to illness or injury can cause muscle atrophy. This is because when a muscle is not used, the body conserves energy by breaking down the unused muscle, leading to a decrease in muscle size and strength. This type of atrophy is known as disuse (physiologic) atrophy and is often reversible with regular exercise and physical therapy.
Ageing is another common cause of muscle atrophy. Sarcopenia, for example, is a type of muscle atrophy characterised by the progressive loss of muscle mass and strength due to the ageing process. As people age, their bodies produce fewer proteins necessary for muscle growth, leading to a reduction in muscle cell size and function. The risk of sarcopenia increases with age, affecting 5-13% of people aged 60 and older and 11-50% of those aged 80 and above.
Malnutrition can also lead to muscle atrophy by impairing the body's ability to absorb nutrients. Conditions such as cachexia, which causes extreme weight loss and muscle atrophy, can develop as a symptom of underlying illnesses like cancer, HIV, or multiple sclerosis. In such cases, malnutrition-related muscle atrophy can be an indirect consequence of the body's inability to absorb nutrients due to the disease.
Medications and injuries can also contribute to muscle atrophy by causing nerve damage. Neurogenic atrophy occurs when nerves connecting to the muscles are damaged, impairing their ability to trigger muscle contractions. As a result, the muscles no longer receive signals from the nerves, leading to a decrease in muscle size and strength. Carpal tunnel syndrome, for instance, can cause nerve and muscle breakdown, resulting in atrophy.
The Stomach: A Muscle or Something Else?
You may want to see also
Explore related products

Physiologic atrophy occurs when muscles are not used enough
Physiologic atrophy, also known as disuse atrophy, occurs when muscles are not used enough. It is caused by a sedentary lifestyle, inadequate nutrition, illness, injury, or other health problems that limit movement. This type of atrophy can often be reversed with exercise and improved nutrition.
When muscles are not used, the body stops wasting energy on maintaining them. As a result, the muscles begin to break down, leading to a decrease in muscle size and strength. This process can start within two to three weeks of muscle disuse. Physiologic atrophy is not limited to skeletal muscles and can also affect the throat muscles, making it difficult to swallow, or the diaphragm, causing breathing difficulties.
The risk of physiologic atrophy is higher for people with seated jobs, health issues that restrict movement, or low activity levels. Older people are also more susceptible to muscle atrophy due to reduced muscle growth-promoting protein production. Additionally, certain medications can contribute to muscle atrophy, either by directly affecting the muscles or as a side effect.
To prevent and treat physiologic atrophy, it is essential to maintain physical activity and a healthy diet. Exercise programs, including swimming and rehabilitation exercises, can help reverse muscle atrophy. Physiologic atrophy is typically a symptom of an underlying issue rather than a disease itself. Therefore, treating the root cause is crucial for effective management.
Muscle Imbalance: Can It Heal Without Intervention?
You may want to see also
Explore related products

Neurogenic atrophy is caused by nerve problems or diseases
Muscle atrophy is the wasting or thinning of muscle mass. It can be caused by muscle disuse or neurogenic conditions. Neurogenic atrophy is a type of muscle atrophy that occurs due to nerve problems or diseases. When nerves connecting to the muscles are damaged, they cannot trigger the muscle contractions required to stimulate muscle activity. As a result, the muscles stop contracting, and the body starts breaking them down, leading to a decrease in muscle size and strength.
Neurogenic atrophy is considered the most severe type of muscle atrophy and tends to occur more suddenly than physiologic atrophy. It is often caused by injuries or diseases affecting the nerves connected to the muscles. Examples of conditions that can lead to neurogenic atrophy include Amyotrophic Lateral Sclerosis (ALS), Guillain-Barre Syndrome, Carpal Tunnel Syndrome, Spinal Cord injuries, and Multiple Sclerosis.
The treatment for neurogenic atrophy depends on the specific cause and severity of the condition. In some cases, it may be treated with a specialised form of physical therapy called electrical stimulation. This involves placing electrodes on the skin over the affected muscles to send electrical impulses that stimulate muscle contractions and help maintain muscle mass and strength. Ultrasound therapy, which uses sound waves to promote muscle healing, may also be recommended.
Unlike physiologic atrophy, neurogenic atrophy typically cannot be reversed due to the physical damage caused to the nerves. However, treatment options can help manage the condition and prevent further muscle deterioration. It is important to consult with a healthcare professional to determine the most appropriate treatment plan for neurogenic atrophy.
Regaining Lost Muscle: Is It Easier the Second Time?
You may want to see also
Explore related products
$9.99

Malnutrition-related atrophy can be caused by conditions that impair nutrient absorption
Muscle atrophy is the wasting or thinning of muscle mass, resulting in a decrease in muscle strength. It can be caused by muscle disuse, neurogenic conditions, malnutrition, age, genetics, or certain medical conditions.
Malnutrition is prevalent in older hospitalized patients and is associated with adverse outcomes. Studies have shown that malnourished older patients experience a decline in muscle strength and mass during hospitalization. Additionally, malnutrition has been identified as a significant and independent risk factor for acute muscle wasting in frail older patients.
The impact of malnutrition on muscle atrophy is not limited to the elderly. Inadequate nutrition, particularly a lack of lean protein, fruits, and vegetables, can impair muscle growth and maintenance across all age groups. Therefore, malnutrition-related atrophy can occur in individuals of any age if their body's ability to absorb nutrients is impaired due to certain medical conditions or other factors affecting nutrient absorption.
Treating malnutrition-related atrophy often involves addressing the underlying conditions that impair nutrient absorption. Additionally, targeted nutritional interventions and dietary changes may be recommended to improve nutrient intake and absorption, thereby supporting muscle health and potentially reversing the effects of atrophy.
Exploring the Intriguing Multi-Bellied Muscles in the Human Body
You may want to see also
Explore related products
$24.32

Muscle atrophy can be treated with physical therapy, functional electric stimulation, or surgery
Muscle atrophy is the wasting or thinning of muscle mass. It can be caused by muscle disuse, malnutrition, age, genetics, lack of physical activity, or certain medical conditions. The two types of muscle atrophy are disuse atrophy and neurogenic atrophy. Disuse atrophy occurs when muscles are unused for a prolonged period, leading to a decrease in muscle mass and strength. This can often be addressed with physical therapy, which helps patients regain muscle strength and stamina. Orthopaedic physical therapists are well-equipped to assist individuals in combating the effects of muscle atrophy and developing tailored exercise programs to restore muscle function.
Neurogenic atrophy, on the other hand, is caused by nerve injuries or diseases that impair the transmission of neurological signals to the muscles. Conditions such as ALS, multiple sclerosis, and spinal cord injuries can lead to neurogenic atrophy. While this type of atrophy cannot be reversed due to the physical damage to nerves, its symptoms can be managed through a specific form of physical therapy called functional electric stimulation (FES). FES employs electrical impulses to activate specific muscles and nerves, causing them to contract and move. This treatment option is particularly useful for individuals experiencing spinal cord injuries or paralysis.
In addition to physical therapy, disuse atrophy can often be reversed through regular exercise and improved nutrition. A healthy diet, combined with an appropriate exercise program, can help rebuild muscle mass and strength. For individuals who are unable to move certain joints, exercises can still be performed with the use of a splint or brace.
In severe cases of muscle atrophy, surgery may be considered as a treatment option. Surgical procedures can address the underlying causes of muscle atrophy, such as nerve compression or damage, and help improve muscle function. However, the decision to undergo surgery depends on various factors, including the patient's overall health, the severity of the atrophy, and the potential risks and benefits of the procedure.
Building Muscle: Effective Strategies for Quick Results
You may want to see also
Frequently asked questions
Muscle atrophy is the wasting or thinning of muscle mass.
Muscle atrophy can be caused by muscle disuse, malnutrition, age, genetics, neurogenic conditions, or certain medical conditions.
Symptoms include a decrease in muscle mass, weakness, numbness, and tingling in the limbs.
Treatment for muscle atrophy includes physical therapy, functional electric stimulation, ultrasound therapy, and in some cases, surgery. Disuse atrophy can be reversed with exercise and a healthy diet.
There are three types of muscle atrophy: physiologic atrophy, pathologic atrophy, and neurogenic atrophy.




































![Practical Muscle Testing and the Treatment of Muscular Atrophies 1897 [Leather Bound]](https://m.media-amazon.com/images/I/617DLHXyzlL._AC_UL320_.jpg)






